Zeggini, Eleftheria

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., et al. (2016) · Human Molecular Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 343

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

Grarup, N., Moltke, I., Andersen, M. K., Dalby, M., Vitting-Seerup, K., Kern, T., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 216

Statistical methods to detect pleiotropy in human complex traits

Hackinger, S., & Zeggini, E. (2017) · Open Biology

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 143

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Youlten, S. E., Kemp, J. P., Logan, J. G., Ghirardello, E. J., Sergio, C. M., Dack, M. R. G., Guilfoyle, S. E., Leitch, V. D., Butterfield, N. C., Komla-Ebri, D., et al. (2021) · Nature Communications

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 133

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

Anderson, C. A., Soranzo, N., Zeggini, E., & Barrett, J. C. (2011) · PLoS Biology

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 114

Whole-genome sequencing analysis of the cardiometabolic proteome

Gilly, A., Park, Y.-C., Png, G., Barysenka, A., Fischer, I., Bjørnland, T., Southam, L., Suveges, D., Neumeyer, S., Rayner, N. W., et al. (2020) · Nature Communications

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 107

Whole-genome sequence-based analysis of thyroid function

Taylor, P. N., Porcu, E., Chew, S., Campbell, P. J., Traglia, M., Brown, S. J., Mullin, B. H., Shihab, H. A., Min, J., Walter, K., et al. (2015) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 104

Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

Southam, L., Soranzo, N., Montgomery, S. B., Frayling, T. M., McCarthy, M. I., Barroso, I., & Zeggini, E. (2009) · Diabetologia

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 103

Estimating genome-wide significance for whole-genome sequencing studies

Xu, C., Tachmazidou, I., Walter, K., Ciampi, A., Zeggini, E., Greenwood, C. M. T., & the UK10K Consortium (2014) · Genetic Epidemiology

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 93

Very low-depth whole-genome sequencing in complex trait association studies

Gilly, A., Southam, L., Suveges, D., Kuchenbaecker, K., Moore, R., Melloni, G. E. M., Hatzikotoulas, K., Farmaki, A.-E., Ritchie, G., Schwartzentruber, J., et al. (2019) · Bioinformatics

Genetic Associations and EpidemiologyGenomics and Phylogenetic Studies

Cited by 93

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

Panoutsopoulou, K., Hatzikotoulas, K., Xifara, D. K., Colonna, V., Farmaki, A.-E., Ritchie, G. R. S., Southam, L., Gilly, A., Tachmazidou, I., Fatumo, S., et al. (2014) · Nature Communications

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 70

Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits

Boraska, V., Davis, O. S. P., Cherkas, L. F., Helder, S. G., Harris, J., Krug, I., Pei‐Chi Liao, T., Treasure, J., Ntalla, I., Karhunen, L., et al. (2012) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Eating Disorders and BehaviorsGenetic Associations and Epidemiology

Cited by 61

Synthetic associations in the context of genome-wide association scan signals

Orozco, G., Barrett, J. C., & Zeggini, E. (2010) · Human Molecular Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 61

Mapping the serum proteome to neurological diseases using whole genome sequencing

Png, G., Barysenka, A., Repetto, L., Navarro, P., Shen, X., Pietzner, M., Wheeler, E., Wareham, N. J., Langenberg, C., Tsafantakis, E., et al. (2021) · Nature Communications

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 55

Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization

Zheng, J., Wheeler, E., Pietzner, M., Andlauer, T. F. M., Yau, M. S., Hartley, A. E., Brumpton, B. M., Rasheed, H., Kemp, J. P., Frysz, M., et al. (2023) · Arthritis & Rheumatology

Bone health and osteoporosis researchGenetic Associations and Epidemiology

Cited by 44

Insights into the molecular underpinning of type 2 diabetes complications

Singh, A., Bocher, O., & Zeggini, E. (2025) · Human Molecular Genetics

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 10

Gene-based whole genome sequencing meta-analysis of 250 circulating proteins in three isolated European populations

Gilly, A., Klaric, L., Park, Y.-C., Png, G., Barysenka, A., Marsh, J. A., Tsafantakis, E., Karaleftheri, M., Dedoussis, G., Wilson, J. F., et al. (2022) · Molecular Metabolism

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 7

Population‐wide copy number variation calling using variant call format files from 6,898 individuals

Png, G., Suveges, D., Park, Y., Walter, K., Kundu, K., Ntalla, I., Tsafantakis, E., Karaleftheri, M., Dedoussis, G., Zeggini, E., et al. (2020) · Genetic Epidemiology

Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology

Cited by 2