Stratakis, Constantine A.

Cushing's syndrome

Lacroix, A., Feelders, R. A., Stratakis, C. A., & Nieman, L. K. (2015) · The Lancet

Pituitary Gland Disorders and TreatmentsAdrenal and Paraganglionic Tumors

Cited by 1,777

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline

Bornstein, S. R., Allolio, B., Arlt, W., Barthel, A., Don-Wauchope, A., Hammer, G. D., Husebye, E. S., Merke, D. P., Murad, M. H., Stratakis, C. A., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersHormonal Regulation and Hypertension

Cited by 1,769

Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex

Kirschner, L. S., Carney, J. A., Pack, S. D., Taymans, S. E., Giatzakis, C., Cho, Y. S., Cho-Chung, Y. S., & Stratakis, C. A. (2000) · Nature Genetics

Genetic factors in colorectal cancerNeurofibromatosis and Schwannoma Cases

Cited by 1,153

Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations

Janeway, K. A., Kim, S. Y., Lodish, M., Nosé, V., Rustin, P., Gaal, J., Dahia, P. L. M., Liegl, B., Ball, E. R., Raygada, M., et al. (2011) · Proceedings of the National Academy of Sciences

Gastrointestinal Tumor Research and TreatmentGenetic factors in colorectal cancer

Cited by 628

An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

Ribeiro, R. C., Sandrini, F., Figueiredo, B., Zambetti, G. P., Michalkiewicz, E., Lafferty, A. R., DeLacerda, L., Rabin, M., Cadwell, C., Sampaio, G., et al. (2001) · Proceedings of the National Academy of Sciences

Adrenal and Paraganglionic TumorsCancer-related Molecular Pathways

Cited by 541

Neuroendocrinology and pathophysiology of the stress system

STRATAKIS, C. A., & CHROUSOS, G. P. (1995) · Annals of the New York Academy of Sciences

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 533

Bone Mineral Density in Women with Depression

Michelson, D., Stratakis, C., Hill, L., Reynolds, J., Galliven, E., Chrousos, G., & Gold, P. (1996) · New England Journal of Medicine

Bone health and osteoporosis researchBone Metabolism and Diseases

Cited by 471

Constitutive activation of PKA catalytic subunit in adrenal Cushing’s syndrome

Beuschlein, F., Fassnacht, M., Assié, G., Calebiro, D., Stratakis, C. A., Osswald, A., Ronchi, C. L., Wieland, T., Sbiera, S., Faucz, F. R., et al. (2014) · New England Journal of Medicine

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 443

Chronic insomnia and activity of the stress system

Vgontzas, A. N., Tsigos, C., Bixler, E. O., Stratakis, C. A., Zachman, K., Kales, A., Vela-Bueno, A., & Chrousos, G. P. (1998) · Journal of Psychosomatic Research

Sleep and related disordersSleep and Wakefulness Research

Cited by 401

Somatic HIF2A Gain-of-Function Mutations in Paraganglioma with Polycythemia

Zhuang, Z., Yang, C., Lorenzo, F., Merino, M., Fojo, T., Kebebew, E., Popovic, V., Stratakis, C. A., Prchal, J. T., & Pacak, K. (2012) · New England Journal of Medicine

Adrenal and Paraganglionic TumorsCancer, Hypoxia, and Metabolism

Cited by 397

ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome

Assié, G., Libé, R., Espiard, S., Rizk-Rabin, M., Guimier, A., Luscap, W., Barreau, O., Lefèvre, L., Sibony, M., Guignat, L., et al. (2013) · New England Journal of Medicine

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 395

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance

Hurley, D. M., Accili, D., Stratakis, C. A., Karl, M., Vamvakopoulos, N., Rorer, E., Constantine, K., Taylor, S. I., & Chrousos, G. P. (1991) · Journal of Clinical Investigation

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 370

Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor

Killian, J. K., Kim, S. Y., Miettinen, M., Smith, C., Merino, M., Tsokos, M., Quezado, M., Smith, W. I., Jahromi, M. S., Xekouki, P., et al. (2013) · Cancer Discovery

Epigenetics and DNA MethylationGastrointestinal Tumor Research and Treatment

Cited by 356

A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

Horvath, A., Boikos, S., Giatzakis, C., Robinson-White, A., Groussin, L., Griffin, K. J., Stein, E., Levine, E., Delimpasi, G., Hsiao, H. P., et al. (2006) · Nature Genetics

Adrenal and Paraganglionic TumorsPhosphodiesterase function and regulation

Cited by 352

Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene

Karl, M., Lamberts, S. W., Detera-Wadleigh, S. D., Encio, I. J., Stratakis, C. A., Hurley, D. M., Accili, D., & Chrousos, G. P. (1993) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 241

ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences

Espiard, S., Drougat, L., Libé, R., Assié, G., Perlemoine, K., Guignat, L., Barrande, G., Brucker-Davis, F., Doullay, F., Lopez, S., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 196

Macronodular Adrenal Hyperplasia due to Mutations in an Armadillo Repeat Containing 5 (ARMC5) Gene: A Clinical and Genetic Investigation

Faucz, F. R., Zilbermint, M., Lodish, M. B., Szarek, E., Trivellin, G., Sinaii, N., Berthon, A., Libé, R., Assié, G., Espiard, S., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 166

Diagnostic tests for children who are referred for the investigation of Cushing syndrome

Batista, D. L., Riar, J., Keil, M., & Stratakis, C. A. (2007) · Pediatrics

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 165

PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development

Drelon, C., Berthon, A., Sahut-Barnola, I., Mathieu, M., Dumontet, T., Rodriguez, S., Batisse-Lignier, M., Tabbal, H., Tauveron, I., Lefrançois-Martinez, A.-M., et al. (2016) · Nature Communications

Wnt/β-catenin signaling in development and cancerAdrenal and Paraganglionic Tumors

Cited by 128

The Aromatase Excess Syndrome Is Associated with Feminization of Both Sexes and Autosomal Dominant Transmission of Aberrant P450 Aromatase Gene Transcription

Stratakis, C. A. (1998) · Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersEstrogen and related hormone effects

Cited by 115

Detection of somatic β-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD)

Tadjine, M., Lampron, A., Ouadi, L., Horvath, A., Stratakis, C. A., & Bourdeau, I. (2008) · Clinical Endocrinology

Adrenal and Paraganglionic TumorsPituitary Gland Disorders and Treatments

Cited by 108

Identification of novel genetic variants in phosphodiesterase 8B ( PDE8B ), a cAMP ‐specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours

Rothenbuhler, A., Horvath, A., Libé, R., Faucz, F. R., Fratticci, A., Raffin Sanson, M. L., Vezzosi, D., Azevedo, M., Levy, I., Almeida, M. Q., et al. (2012) · Clinical Endocrinology

Adrenal and Paraganglionic TumorsPhosphodiesterase function and regulation

Cited by 96

A large family with Carney complex caused by the S147G PRKAR1A mutation shows a unique spectrum of disease including adrenocortical cancer

Anselmo, J., Medeiros, S., Carneiro, V., Greene, E., Levy, I., Nesterova, M., Lyssikatos, C., Horvath, A., Carney, J. A., & Stratakis, C. A. (2012) · The Journal of Clinical Endocrinology & Metabolism

Adrenal and Paraganglionic TumorsPituitary Gland Disorders and Treatments

Cited by 81

Skin steroidogenesis in health and disease

Nikolakis, G., Stratakis, C. A., Kanaki, T., Slominski, A., & Zouboulis, C. C. (2016) · Reviews in Endocrine and Metabolic Disorders

Dermatology and Skin DiseasesAdrenal Hormones and Disorders

Cited by 76