A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

Activating Mutations of the Stimulatory G Protein in the McCune–Albright Syndrome

Weinstein, L. S., Shenker, A., Gejman, P. V., Merino, M. J., Friedman, E., & Spiegel, A. M. (1991) · New England Journal of Medicine · doi:10.1056/nejm199112123252403 · Cited by 1,680 · see citing works

Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex

Kirschner, L. S., Carney, J. A., Pack, S. D., Taymans, S. E., Giatzakis, C., Cho, Y. S., Cho-Chung, Y. S., & Stratakis, C. A. (2000) · Nature Genetics · doi:10.1038/79238 · Cited by 1,153 · see citing works

Clinical and Molecular Features of the Carney Complex: Diagnostic Criteria and Recommendations for Patient Evaluation

Stratakis, C. A., Kirschner, L. S., & Carney, J. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7903 · Cited by 805 · see citing works

DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

Millar, J. K., Pickard, B. S., Mackie, S., James, R., Christie, S., Buchanan, S. R., Malloy, M. P., Chubb, J. E., Huston, E., Baillie, G. S., et al. (2005) · Science · doi:10.1126/science.1112915 · Cited by 648 · see citing works

Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

Lehnart, S. E., Wehrens, X. H. T., Reiken, S. R., Warrier, S., Belevych, A. E., Harvey, R. D., Richter, W., Jin, S.-L. C., Conti, M., & Marks, A. R. (2005) · Cell · doi:10.1016/j.cell.2005.07.030 · Cited by 518 · see citing works

Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex

Kirschner, L. S. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.20.3037 · Cited by 406 · see citing works

Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

Fawcett, L., Baxendale, R. W., Stacey, P., McGrouther, C., Harrow, I., Soderling, S. H., Hetman, J., Beavo, J. A., & Phillips, S. C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3702 · Cited by 359 · see citing works

Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

Masciarelli, S., Horner, K., Liu, C., Park, S. H., Hinckley, M. D., Hockman, S. C., Nedachi, T., Jin, C., Conti, M., & Manganiello, V. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21804 · Cited by 260 · see citing works

Autosomal recessive retinitis pigmentosa caused by mutations in the α subunit of rod cGMP phosphodiesterase

Huang, S. H., Pittler, S. J., Huang, X., Oliveira, L., Berson, E. L., & Dryja, T. P. (1995) · Nature Genetics · doi:10.1038/ng1295-468 · Cited by 252 · see citing works

Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity.

Bertherat, J. Y., Groussin, L., Sandrini, F., Matyakhina, L., Bei, T. A., Stergiopoulos, S. G., Papageorgiou, T., Bourdeau, I., Kirschner, L. S., Vincent-Dejean, C., et al. (2003) · PubMed · Cited by 250 · see citing works

Heterozygous missense mutation in the rod cGMP phosphodiesterase β–subunit gene in autosomal dominant stationary night blindness

Gal, A., Orth, U., Baehr, W., SCHWINGER, E., & Rosenberg, T. (1994) · Nature Genetics · doi:10.1038/ng0594-64 · Cited by 245 · see citing works

Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice

Jin, S.-L. C., Richard, F. J., Kuo, W.-P., D’Ercole, A. J., & Conti, M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.21.11998 · Cited by 232 · see citing works

Mutations of thePRKAR1AGene in Cushing’s Syndrome due to Sporadic Primary Pigmented Nodular Adrenocortical Disease

Groussin, L., Jullian, E. H., Perlemoine, K., Louvel, A., Leheup, B., LUTON, J. P., BERTAGNA, X. Y., & Bertherat, J. Y. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020592 · Cited by 168 · see citing works

Clinical and Genetic Analysis of Primary Bilateral Adrenal Diseases (Micro- and Macronodular Disease) Leading to Cushing Syndrome

Stratakis, C. A., & Kirschner, L. S. (1998) · Hormone and Metabolic Research · doi:10.1055/s-2007-978914 · Cited by 152 · see citing works

Isolation and Characterization of Two Novel Phosphodiesterase PDE11A Variants Showing Unique Structure and Tissue-specific Expression

Yuasa, K., Kotera, J., Fujishige, K., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003041200 · Cited by 142 · see citing works

Cyclical Cushing Syndrome Presenting in Infancy: An Early Form of Primary Pigmented Nodular Adrenocortical Disease, or a New Entity?

Gunther, D. F., Bourdeau, I., Matyakhina, L., Cassarino, D. S., Kleiner, D. E., Griffin, K., Courkoutsakis, N. A., Abu-Asab, M. S., Tsokos, M., Keil, M. F., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032247 · Cited by 117 · see citing works

Genomic organization of the human phosphodiesterase PDE11A gene

Yuasa, K., Kanoh, Y., Okumura, K., et al. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.01866.x · Cited by 94 · see citing works

Phosphodiesterase 11 (PDE11) regulation of spermatozoa physiology

Wayman, C., Phillips, S., Lunny, C., et al. (2005) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901307 · Cited by 85 · see citing works

Cloning and characterization of two splice variants of human phosphodiesterase 11A

Hetman, J., Robas, N. M., Baxendale, R. W., Fidock, M. D., Phillips, S. C., Soderling, S. H., & Beavo, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.200355397 · Cited by 84 · see citing works

Cyclic AMP‐Dependent Signaling Aberrations in Macronodular Adrenal Disease

Bourdeau, I., & Stratakis, C. A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04339.x · Cited by 72 · see citing works

3′,5′-Cyclic nucleotide phosphodiesterase 11A: localization in human tissues

Loughney, K., Taylor, J., & Florio, V. A. (2005) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901317 · Cited by 72 · see citing works

Induction of Specific Phosphodiesterase Isoforms by Constitutive Activation of the cAMP Pathway in Autonomous Thyroid Adenomas1

Persani, L., Lania, A. G., Alberti, L., Romoli, R., Mantovani, G., Filetti, S., Spada, A., & Conti, M. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6712 · Cited by 69 · see citing works

Expression of PDE11A in Normal and Malignant Human Tissues

D’Andrea, M. R., Qiu, Y., Haynes‐Johnson, D., et al. (2005) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.5a6625.2005 · Cited by 64 · see citing works

Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A)

Yuasa, K., Ohgaru, T., Asahina, M., et al. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.02366.x · Cited by 60 · see citing works

Human Ca2+/calmodulin-dependent phosphodiesterase PDE1A: novel splice variants, their specific expression, genomic organization, and chromosomal localization

Michibata, H., Yanaka, N., Kanoh, Y., et al. (2001) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(00)00293-1 · Cited by 55 · see citing works

Induction of Specific Phosphodiesterase Isoforms by Constitutive Activation of the cAMP Pathway in Autonomous Thyroid Adenomas

Persani, L. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.8.2872 · Cited by 50 · see citing works

Analysis and visualization of chromosomal abnormalities in SNP data with SNPscan

Ting, J. C., Ye, Y., Thomas, G. H., et al. (2006) · BMC Bioinformatics · doi:10.1186/1471-2105-7-25 · Cited by 43 · see citing works

Phosphodiesterase 11 (PDE11): is it a player in human testicular function?

Francis, S. H. (2005) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901377 · Cited by 36 · see citing works

Phyllodulcin, a Constituent of “Amacha”, Inhibits Phosphodiesterase in Bovine Adrenocortical Cells

Kawamura, M., Kagata, M., Masaki, E., et al. (2002) · Pharmacology & Toxicology · doi:10.1034/j.1600-0773.2002.900209.x · Cited by 20 · see citing works

EXTRAGONADAL GERM CELL TUMOR WITH HIGH SERUM LEVELS OF DU-PAN-2

Maeda, Y., Fujiwara, N., Yoshino, T., et al. (2002) · The Journal of Urology · doi:10.1016/s0022-5347(05)65426-2 · Cited by 19 · see citing works

Constitutive activation of PKA catalytic subunit in adrenal Cushing’s syndrome

Beuschlein, F., Fassnacht, M., Assié, G., Calebiro, D., Stratakis, C. A., Osswald, A., Ronchi, C. L., Wieland, T., Sbiera, S., Faucz, F. R., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1310359 · Cited by 443 · see citing works

Adrenal incidentaloma

Sherlock, M., Scarsbrook, A., Abbas, A., Fraser, S., Limumpornpetch, P., Dineen, R., & Stewart, P. M. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa008 · Cited by 347 · see citing works

Recurrent somatic mutations underlie corticotropin-independent Cushing’s syndrome

Sato, Y., Maekawa, S., Ishii, R., Sanada, M., Morikawa, T., Shiraishi, Y., Yoshida, K., Nagata, Y., Sato-Otsubo, A., Yoshizato, T., et al. (2014) · Science · doi:10.1126/science.1252328 · Cited by 209 · see citing works

<i>ARMC5</i> Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences

Espiard, S., Drougat, L., Libé, R., Assié, G., Perlemoine, K., Guignat, L., Barrande, G., Brucker-Davis, F., Doullay, F., Lopez, S., et al. (2015) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2014-4204 · Cited by 196 · see citing works

Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

Arnaud-Lopez, L., Usala, G., Ceresini, G., Mitchell, B. D., Pilia, M. G., Piras, M. G., Sestu, N., Maschio, A., Busonero, F., Albai, G., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.04.019 · Cited by 139 · see citing works

Wnt/β-catenin signalling in adrenal physiology and tumour development

Berthon, A., Martinez, A., Bertherat, J., & Val, P. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.009 · Cited by 125 · see citing works

Detection of somatic β-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD)

Tadjine, M., Lampron, A., Ouadi, L., Horvath, A., Stratakis, C. A., & Bourdeau, I. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03273.x · Cited by 108 · see citing works

60 YEARS OF POMC: Adrenal and extra-adrenal functions of ACTH

Gallo-Payet, N. (2016) · Journal of Molecular Endocrinology · doi:10.1530/jme-15-0257 · Cited by 98 · see citing works

Identification of novel genetic variants in phosphodiesterase 8B ( <scp> <i>PDE8B</i> </scp> ), a <scp>cAMP</scp> ‐specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours

Rothenbuhler, A., Horvath, A., Libé, R., Faucz, F. R., Fratticci, A., Raffin Sanson, M. L., Vezzosi, D., Azevedo, M., Levy, I., Almeida, M. Q., et al. (2012) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2012.04366.x · Cited by 96 · see citing works

Genetic landscape of sporadic unilateral adrenocortical adenomas without PRKACA p.Leu206Arg mutation

Ronchi, C. L., Di Dalmazi, G., Faillot, S., Sbiera, S., Assié, G., Weigand, I., Calebiro, D., Schwarzmayr, T., Appenzeller, S., Rubin, B., et al. (2016) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2016-1586 · Cited by 93 · see citing works

Multiple aberrant hormone receptors in Cushing’s syndrome

Ghorayeb, N. E., Bourdeau, I., & Lacroix, A. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0200 · Cited by 90 · see citing works

Genetics of tumors of the adrenal cortex

Bonnet-Serrano, F., & Bertherat, J. (2018) · Endocrine Related Cancer · doi:10.1530/erc-17-0361 · Cited by 80 · see citing works

Adrenocortical hyperplasia: A multifaceted disease

Bourdeau, I., Parisien-La Salle, S., & Lacroix, A. (2020) · Best Practice &amp; Research Clinical Endocrinology &amp; Metabolism · doi:10.1016/j.beem.2020.101386 · Cited by 48 · see citing works

An update on adrenal endocrinology: significant discoveries in the last 10 years and where the field is heading in the next decade

Kamilaris, C. D. C., & Stratakis, C. A. (2018) · HORMONES · doi:10.1007/s42000-018-0072-y · Cited by 7 · see citing works

ACTH-Independent Cushing’s Syndrome: Primary Pigmented Nodular Adrenal Disease in the Context of Carney’s Complex

Stratakis, C. A. (2010) · Humana Press eBooks · doi:10.1007/978-1-60327-449-4_18 · Cited by 1 · see citing works

Carney complex and McCune Albright syndrome: An overview of clinical manifestations and human molecular genetics

Salpea, P., & Stratakis, C. A. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.08.022 · Cited by 121 · see citing works

Harvey Cushing Treated the First Known Patient With Carney Complex

Tsay, C. J., Stratakis, C. A., Faucz, F. R., London, E., Stathopoulou, C., Allgäuer, M., Quezado, M., Dagradi, T., Spencer, D. D., & Lodish, M. B. (2017) · Journal of the Endocrine Society · doi:10.1210/js.2017-00283 · Cited by 13 · see citing works

Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes

Bimpaki, E. I., Nesterova, M., & Stratakis, C. A. (2009) · European Journal of Endocrinology · doi:10.1530/eje-09-0027 · Cited by 39 · see citing works

Cushing’s Syndrome Secondary to Adrenocorticotropin-Independent Macronodular Adrenocortical Hyperplasia due to Activating Mutations ofGNAS1Gene

Fragoso, M. C. B. V., Domenice, S., Latronico, A. C., Martin, R. M., Pereira, M. A. A., Zerbini, M. C. N., Lucón, A. M., & Mendonca, B. B. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021362 · Cited by 189 · see citing works