Huguenard, John R.

Neocortical excitation/inhibition balance in information processing and social dysfunction

Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 2,454

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

Paşca, A. M., Sloan, S. A., Clarke, L. E., Tian, Y., Makinson, C. D., Huber, N., Kim, C. H., Park, J.-Y., O'Rourke, N. A., Nguyen, K. D., et al. (2015) · Nature Methods

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 1,609

Assembly of functionally integrated human forebrain spheroids

Birey, F., Andersen, J., Makinson, C. D., Islam, S., Wei, W., Huber, N., Fan, H. C., Metzler, K. R. C., Panagiotakos, G., Thom, N., et al. (2017) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 1,365

A call for transparent reporting to optimize the predictive value of preclinical research

Landis, S. C., Amara, S. G., Asadullah, K., Austin, C. P., Blumenstein, R., Bradley, E. W., Crystal, R. G., Darnell, R. B., Ferrante, R. J., Fillit, H., et al. (2012) · Nature

Animal testing and alternativesMeta-analysis and systematic reviews

Cited by 1,196

Reliability of human cortical organoid generation

Yoon, S.-J., Elahi, L. S., Pașca, A. M., Marton, R. M., Gordon, A., Revah, O., Miura, Y., Walczak, E. M., Holdgate, G. M., Fan, H. C., et al. (2019) · Nature Methods

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 507

Maturation and circuit integration of transplanted human cortical organoids

Revah, O., Gore, F., Kelley, K. W., Andersen, J., Sakai, N., Chen, X., Li, M.-Y., Birey, F., Yang, X., Saw, N. L., et al. (2022) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 504

Anatomically defined and functionally distinct dorsal raphe serotonin sub-systems

Ren, J., Friedmann, D., Xiong, J., Liu, C. D., Ferguson, B. R., Weerakkody, T., DeLoach, K. E., Ran, C., Pun, A., Sun, Y., et al. (2018) · Cell

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 498

Cholinergic Switching Within Neocortical Inhibitory Networks

Xiang, Z., Huguenard, J. R., & Prince, D. A. (1998) · Science

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 438

Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures

Marton, R. M., Miura, Y., Sloan, S. A., Li, Q., Revah, O., Levy, R. J., Huguenard, J. R., & Pașca, S. P. (2019) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 362

Breathing control center neurons that promote arousal in mice

Yackle, K., Schwarz, L. A., Kam, K., Sorokin, J. M., Huguenard, J. R., Feldman, J. L., Luo, L., & Krasnow, M. A. (2017) · Science

Neuroscience of respiration and sleepSleep and Wakefulness Research

Cited by 282

Atlas of the aging mouse brain reveals white matter as vulnerable foci

Hahn, O., Foltz, A. G., Atkins, M., Kedir, B., Moran-Losada, P., Guldner, I. H., Munson, C., Kern, F., Pálovics, R., Lu, N., et al. (2023) · Cell

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 213

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome

Khan, T. A., Revah, O., Gordon, A., Yoon, S.-J., Krawisz, A. K., Goold, C., Sun, Y., Kim, C. H., Tian, Y., Li, M.-Y., et al. (2020) · Nature Medicine

Pluripotent Stem Cells ResearchGenomic variations and chromosomal abnormalities

Cited by 186

Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway

Kim, J.-I., Miura, Y., Li, M.-Y., Revah, O., Selvaraj, S., Birey, F., Meng, X., Thete, M. V., Pavlov, S. D., Andersen, J., et al. (2024) · Neuron

Ion channel regulation and functionNeural dynamics and brain function

Cited by 59