Rensen, Patrick C.N.

Inflammasome is a central player in the induction of obesity and insulin resistance

Stienstra, R., van Diepen, J. A., Tack, C. J., Zaki, M. H., van de Veerdonk, F. L., Perera, D., Neale, G. A., Hooiveld, G. J., Hijmans, A., Vroegrijk, I., et al. (2011) · Proceedings of the National Academy of Sciences

Adipokines, Inflammation, and Metabolic DiseasesInflammasome and immune disorders

Cited by 727

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

Li, Z., Yi, C.-X., Katiraei, S., Kooijman, S., Zhou, E., Chung, C. K., Gao, Y., van den Heuvel, J. K., Meijer, O. C., Berbée, J. F. P., et al. (2018) · Gut

Regulation of Appetite and ObesityGut microbiota and health

Cited by 674

Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation

Blondin, D. P., Nielsen, S., Kuipers, E. N., Severinsen, M. C., Jensen, V. H., Miard, S., Jespersen, N. Z., Kooijman, S., Boon, M. R., Fortin, M., et al. (2020) · Cell Metabolism

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 331

Apolipoprotein E Protects Against Bacterial Lipopolysaccharide-induced Lethality

Van Oosten, M., Rensen, P. C. N., Van Amersfoort, E. S., Van Eck, M., Van Dam, A.-M., Brevé, J. J. P., Vogel, T., Panet, A., Van Berkel, T. J. C., & Kuiper, J. (2001) · Journal of Biological Chemistry

Sepsis Diagnosis and TreatmentImmune Response and Inflammation

Cited by 186

The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism?

Willems van Dijk, K., Rensen, P. C., Voshol, P. J., & Havekes, L. M. (2004) · Current Opinion in Lipidology

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 154

Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise

Catoire, M., Alex, S., Paraskevopulos, N., Mattijssen, F., Evers-van Gogh, I., Schaart, G., Jeppesen, J., Kneppers, A., Mensink, M., Voshol, P. J., et al. (2014) · Proceedings of the National Academy of Sciences

Lipid metabolism and disordersPeroxisome Proliferator-Activated Receptors

Cited by 150

Apolipoprotein E Effectively Inhibits Lipoprotein Lipase-mediated Lipolysis of Chylomicron-like Triglyceride-rich Lipid Emulsions and

Rensen, P. C. N., & van Berkel, T. J. C. (1996) · Journal of Biological Chemistry

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 144

Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice

Kooijman, S., Wang, Y., Parlevliet, E. T., Boon, M. R., Edelschaap, D., Snaterse, G., Pijl, H., Romijn, J. A., & Rensen, P. C. N. (2015) · Diabetologia

Adipose Tissue and MetabolismRegulation of Appetite and Obesity

Cited by 140

Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies

Geerling, J. J., Boon, M. R., Kooijman, S., Parlevliet, E. T., Havekes, L. M., Romijn, J. A., Meurs, I. M., & Rensen, P. C. N. (2014) · Journal of Lipid Research

Adipose Tissue and MetabolismRegulation of Appetite and Obesity

Cited by 137

ApoE Plasma Levels and Risk of Cardiovascular Mortality in Old Age

Mooijaart, S. P., Berbée, J. F. P., van Heemst, D., Havekes, L. M., de Craen, A. J. M., Slagboom, P. E., Rensen, P. C. N., & Westendorp, R. G. J. (2006) · PLoS Medicine

Lipoproteins and Cardiovascular HealthParaoxonase enzyme and polymorphisms

Cited by 129

Exendin‐4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration

Wang, Y., Parlevliet, E. T., Geerling, J. J., van der Tuin, S. J. L., Zhang, H., Bieghs, V, Jawad, A. H. M., Shiri‐Sverdlov, R., Bot, I., de Jager, S. C. A., et al. (2014) · British Journal of Pharmacology

Atherosclerosis and Cardiovascular DiseasesLiver Disease Diagnosis and Treatment

Cited by 126

Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: A pre-specified secondary study on ectopic fat accumulation

Bizino, M. B., Jazet, I. M., de Heer, P., van Eyk, H. J., Dekkers, I. A., Rensen, P. C. N., Paiman, E. H. M., Lamb, H. J., & Smit, J. W. (2020) · Diabetologia

Diabetes Treatment and ManagementCardiovascular Disease and Adiposity

Cited by 123

Human recombinant apolipoprotein E redirects lipopolysaccharide from Kupffer cells to liver parenchymal cells in rats In vivo.

Rensen, P. C., Oosten, M., Bilt, E., Eck, M., Kuiper, J., & Berkel, T. J. (1997) · Journal of Clinical Investigation

Immune Response and InflammationNanoparticle-Based Drug Delivery

Cited by 113

Time-restricted eating with or without low-carbohydrate diet reduces visceral fat and improves metabolic syndrome: A randomized trial

He, M., Wang, J., Liang, Q., Li, M., Guo, H., Wang, Y., Deji, C., Sui, J., Wang, Y.-W., Liu, Y., et al. (2022) · Cell Reports Medicine

Dietary Effects on HealthDiet and metabolism studies

Cited by 111

The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis

Goudriaan, J. R., Santo, S. M. S. E., Voshol, P. J., Teusink, B., van Dijk, K. W., van Vlijmen, B. J. M., Romijn, J. A., Havekes, L. M., & Rensen, P. C. N. (2004) · Journal of Lipid Research

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 100

GLP-1 Receptor Activation Inhibits VLDL Production and Reverses Hepatic Steatosis by Decreasing Hepatic Lipogenesis in High-Fat-Fed APOE*3-Leiden Mice

Parlevliet, E. T., Wang, Y., Geerling, J. J., Schröder-Van der Elst, J. P., Picha, K., O'Neil, K., Stojanovic-Susulic, V., Ort, T., Havekes, L. M., Romijn, J. A., et al. (2012) · PLoS ONE

Lipid metabolism and disordersLiver Disease Diagnosis and Treatment

Cited by 97

A double-blind, placebo-controlled, randomised trial to assess the effect of liraglutide on ectopic fat accumulation in South Asian type 2 diabetes patients

van Eyk, H. J., Paiman, E. H. M., Bizino, M. B., de Heer, P., Geelhoed-Duijvestijn, P. H., Kharagjitsingh, A. V., Smit, J. W. A., Lamb, H. J., Rensen, P. C. N., & Jazet, I. M. (2019) · Cardiovascular Diabetology

Diabetes Treatment and ManagementCardiovascular Disease and Adiposity

Cited by 90

Apolipoprotein E Is Resistant to Intracellular Degradation in Vitro and in Vivo

Rensen, P. C. N., Jong, M. C., van Vark, L. C., van der Boom, H., Hendriks, W. L., van Berkel, T. J. C., Biessen, E. A. L., & Havekes, L. M. (2000) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 86

A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the relationship between sleep and insulin resistance

van den Berg, R., Mook-Kanamori, D. O., Donga, E., van Dijk, M., van Dijk, J. G., Lammers, G.-J., van Kralingen, K. W., Prehn, C., Adamski, J., Romijn, J. A., et al. (2016) · Archives of Biochemistry and Biophysics

Sleep and Work-Related FatigueSleep and related disorders

Cited by 55

Twelve weeks of exenatide treatment increases [18F] fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males

Janssen, L. G. M., Nahon, K. J., Bracké, K. F. M., van den Broek, D., Smit, R., Sardjoe Mishre, A. S. D., Koorneef, L. L., Martinez-Tellez, B., Burakiewicz, J., Kan, H. E., et al. (2020) · Metabolism

Adipose Tissue and MetabolismDiabetes Treatment and Management

Cited by 54

Liraglutide decreases energy expenditure and does not affect the fat fraction of supraclavicular brown adipose tissue in patients with type 2 diabetes

van Eyk, H. J., Paiman, E. H. M., Bizino, M. B., IJzermans, S. L., Kleiburg, F., Boers, T. G. W., Rappel, E. J., Burakiewicz, J., Kan, H. E., Smit, J. W. A., et al. (2020) · Nutrition, Metabolism and Cardiovascular Diseases

Adipose Tissue and MetabolismDiabetes Treatment and Management

Cited by 54

Gender-dependent effects of high-fat lard diet on cardiac function in C57Bl/6J mice

Louwe, M. C., van der Hoorn, J. W. A., van den Berg, S. A. A., Jukema, J. W., Romijn, J. A., Willems van Dijk, K., Rensen, P. C. N., Smit, J. W. A., & Steendijk, P. (2012) · Applied Physiology Nutrition and Metabolism

Cardiovascular Function and Risk FactorsCardiovascular Disease and Adiposity

Cited by 29

Apolipoprotein CI Knock-Out Mice Display Impaired Memory Functions

Berbée, J. F. P., Vanmierlo, T., Abildayeva, K., Blokland, A., Jansen, P. J., Lütjohann, D., Gautier, T., Sijbrands, E., Prickaerts, J., Hadfoune, M., et al. (2011) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 25

Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins

Vos, D. Y., Wijers, M., Smit, M., Huijkman, N., Kloosterhuis, N. J., Wolters, J. C., Tissink, J. J., Pronk, A. C. M., Kooijman, S., Rensen, P. C. N., et al. (2023) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cholesterol and Lipid MetabolismCellular transport and secretion

Cited by 16