Fu, Yang-Xin

Innate and adaptive immune cells in the tumor microenvironment

Gajewski, T. F., Schreiber, H., & Fu, Y.-X. (2013) · Nature Immunology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 4,148

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Deng, L., Liang, H., Xu, M., Yang, X., Burnette, B., Arina, A., Li, X.-D., Mauceri, H., Beckett, M., Darga, T., et al. (2014) · Immunity

interferon and immune responsesImmunotherapy and Immune Responses

Cited by 2,182

Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

Lee, Y., Auh, S. L., Wang, Y., Burnette, B., Wang, Y., Meng, Y., Beckett, M., Sharma, R., Chin, R., Tu, T., et al. (2009) · Blood

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,324

Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

He, Y., Fu, L., Li, Y., Wang, W., Gong, M., Zhang, J., Dong, X., Huang, J., Wang, Q., Mackay, C. R., et al. (2021) · Cell Metabolism

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 729

The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity

Park, S., Jiang, Z., Mortenson, E. D., Deng, L., Radkevich-Brown, O., Yang, X., Sattar, H., Wang, Y., Brown, N. K., Greene, M., et al. (2010) · Cancer Cell

HER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 577

PD‐L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade

Peng, Q., Qiu, X., Zhang, Z., Zhang, S., Zhang, Y., Liang, Y., Guo, J., Peng, H., Chen, M., Fu, Y.-X., et al. (2020) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 553

Type I interferon response and innate immune sensing of cancer

Fuertes, M. B., Woo, S.-R., Burnett, B., Fu, Y.-X., & Gajewski, T. F. (2013) · Trends in Immunology

interferon and immune responsesImmunotherapy and Immune Responses

Cited by 375

Adaptive immune cells temper initial innate responses

Dong Kim, K., Zhao, J., Auh, S., Yang, X., Du, P., Tang, H., & Fu, Y.-X. (2007) · Nature Medicine

Immune Response and InflammationT-cell and B-cell Immunology

Cited by 348

LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration

Deng, M., Gui, X., Kim, J., Xie, L., Chen, W., Li, Z., He, L., Chen, Y., Chen, H., Luo, W., et al. (2018) · Nature

Immune Cell Function and InteractionCancer Immunotherapy and Biomarkers

Cited by 305

Tumor-infiltrating T lymphocytes: Friends or foes?

Yu, P., & Fu, Y.-X. (2006) · Laboratory Investigation

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 299

DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

Lu, C., Guan, J., Lu, S., Jin, Q., Rousseau, B., Lu, T., Stephens, D., Zhang, H., Zhu, J., Yang, M., et al. (2021) · Cancer Cell

Cancer Immunotherapy and Biomarkersinterferon and immune responses

Cited by 285

The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy

Wang, G.-Z., Zhang, L., Zhao, X.-C., Gao, S.-H., Qu, L.-W., Yu, H., Fang, W.-F., Zhou, Y.-C., Liang, F., Zhang, C., et al. (2019) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 213

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control

Sun, Z., Ren, Z., Yang, K., Liu, Z., Cao, S., Deng, S., Xu, L., Liang, Y., Guo, J., Bian, Y., et al. (2019) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 211

Targeting CD137 enhances the efficacy of cetuximab

Kohrt, H. E., Colevas, A. D., Houot, R., Weiskopf, K., Goldstein, M. J., Lund, P., Mueller, A., Sagiv-Barfi, I., Marabelle, A., Lira, R., et al. (2014) · Journal of Clinical Investigation

Immune Cell Function and InteractionMonoclonal and Polyclonal Antibodies Research

Cited by 160

Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota

Guo, X., Liang, Y., Zhang, Y., Lasorella, A., Kee, B. L., & Fu, Y.-X. (2015) · Immunity

IL-33, ST2, and ILC PathwaysGut microbiota and health

Cited by 138

AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

Li, H., Liu, Z., Liu, L., Zhang, H., Han, C., Girard, L., Park, H., Zhang, A., Dong, C., Ye, J., et al. (2022) · Cell Reports Medicine

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 102

Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity

Zhang, C., Feng, J., Du, J., Zhuo, Z., Yang, S., Zhang, W., Wang, W., Zhang, S., Iwakura, Y., Meng, G., et al. (2018) · Cellular & Molecular Immunology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 99

Type I IFN activating type I dendritic cells for antitumor immunity

Liang, Y., Hannan, R., & Fu, Y.-X. (2021) · Clinical Cancer Research

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 91

T cell-derived lymphotoxin regulates liver regeneration

Tumanov, A. V., Koroleva, E. P., Christiansen, P. A., Khan, M. A., Ruddy, M. J., Burnette, B., Papa, S., Franzoso, G., Nedospasov, S. A., Fu, Y., et al. (2009) · Gastroenterology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 89

Effective anti-neu-initiated antitumor responses require the complex role of CD4+ T cells

Mortenson, E. D., Park, S., Jiang, Z., Wang, S., & Fu, Y.-X. (2013) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 66

B and T Lymphocyte Attenuator Tempers Early Infection Immunity

Sun, Y., Brown, N. K., Ruddy, M. J., Miller, M. L., Lee, Y., Wang, Y., Murphy, K. M., Pfeffer, K., Chen, L., Kaye, J., et al. (2009) · The Journal of Immunology

T-cell and B-cell ImmunologyImmune Response and Inflammation

Cited by 51

Lymphotoxin β Receptor (LtβR): Dual Roles in Demyelination and Remyelination and Successful Therapeutic Intervention Using LtβR–Ig Protein

Plant, S. R., Iocca, H. A., Wang, Y., Thrash, J. C., O'Connor, B. P., Arnett, H. A., Fu, Y.-X., Carson, M. J., & Ting, J. P.-Y. (2007) · The Journal of Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 51

B and T Lymphocyte Attenuator Down-regulation by HIV-1 Depends on Type I Interferon and Contributes to T-Cell Hyperactivation

Zhang, Z., Xu, X., Lu, J., Zhang, S., Gu, L., Fu, J., Jin, L., Li, H., Zhao, M., Zhang, J., et al. (2011) · The Journal of Infectious Diseases

HIV Research and TreatmentT-cell and B-cell Immunology

Cited by 35

Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth

Zheng, H., Zou, W., Shen, J., Xu, L., Wang, S., Fu, Y.-X., & Fan, W. (2016) · Stem Cells Translational Medicine

Mesenchymal stem cell researchImmune cells in cancer

Cited by 28