Tumor-infiltrating T lymphocytes: Friends or foes?

Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

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Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

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The expanding universe of T-cell subsets: Th1, Th2 and more

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

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N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf -T olerance and N egative C ontrol of I mmune R esponses

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The Three Es of Cancer Immunoediting

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Cancer immunotherapy: moving beyond current vaccines

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

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Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

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Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

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A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

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CD4+CD25+ suppressor T cells: more questions than answers

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Help for cytotoxic-T-cell responses is mediated by CD40 signalling

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A Randomized Comparison of Antiplatelet and Anticoagulant Therapy after the Placement of Coronary-Artery Stents

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

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Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

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Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

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CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

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Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

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Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma

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Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

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The Central Role of CD4+ T Cells in the Antitumor Immune Response

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Regulatory T cells in transplantation tolerance

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Progress in human tumour immunology and immunotherapy

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Model Predicting Survival in Stage I Melanoma Based on Tumor Progression

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

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Immunity to Methylcholanthrene-Induced Sarcomas

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Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

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CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.

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Regulatory T cells in the control of immune pathology

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CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

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Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

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Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

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Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

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The Th1/Th2 paradigm

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Vaccination with cytotoxic T lymphocyte epitope‐containing peptide protects against a tumor induced by human papillomavirus type 16‐transformed cells

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LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

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Cutting Edge: Regulatory T Cells from Lung Cancer Patients Directly Inhibit Autologous T Cell Proliferation

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CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection

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DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

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Concomitant Tumor Immunity to a Poorly Immunogenic Melanoma Is Prevented by Regulatory T Cells

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Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma

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Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer

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Histologic Assessment of Tumor-Associated CD45+ Cell Numbers Is an Independent Predictor of Prognosis in Small Cell Lung Cancer

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IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition

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PD-L1 Expression Confers Better Prognosis in Locally Advanced Oral Squamous Cell Carcinoma

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T Cells in Gastric Cancer: Friends or Foes

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Differential modulation and prognostic values of immune-escape genes in uveal melanoma

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Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others

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High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma

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Peritransplant Lymphopenia Is a Novel Prognostic Factor in Recurrence of Hepatocellular Carcinoma After Liver Transplantation

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The ratio of intra‐tumoral regulatory T cells (Foxp3+)/helper T cells (CD4+) is a prognostic factor and associated with recurrence pattern in gastric cardia cancer

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Pretransplant Lymphopenia Is a Novel Prognostic Factor in Cytomegalovirus and Noncytomegalovirus Invasive Infections After Liver Transplantation

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Niche Inheritance: A Cooperative Pathway to Enhance Cancer Cell Fitness Through Ecosystem Engineering

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The Interplay of Autophagy and Tumor Microenvironment in Colorectal Cancer—Ways of Enhancing Immunotherapy Action

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Decoding Immune Heterogeneity of Triple Negative Breast Cancer and Its Association with Systemic Inflammation

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Transient Foxp3+ regulatory T‐cell depletion enhances therapeutic anticancer vaccination targeting the immune‐stimulatory properties of NKT cells

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KIF2C Is a Novel Prognostic Biomarker and Correlated with Immune Infiltration in Endometrial Cancer

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Immunomodulatory Yersinia outer proteins (Yops)–useful tools for bacteria and humans alike

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Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values

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The Immune Microenvironment in Penile Cancer and Rationale for Immunotherapy

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Variation of Tumor-Infiltrating Lymphocytes in Human Cancers: Controversy on Clinical Significance

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