Svenningsson, Per

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

Valjent, E., Pascoli, V., Svenningsson, P., Paul, S., Enslen, H., Corvol, J.-C., Stipanovich, A., Caboche, J., Lombroso, P. J., Nairn, A. C., et al. (2005) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 614

Alterations in 5-HT 1B Receptor Function by p11 in Depression-Like States

Svenningsson, P., Chergui, K., Rachleff, I., Flajolet, M., Zhang, X., Yacoubi, M. E., Vaugeois, J.-M., Nomikos, G. G., & Greengard, P. (2006) · Science

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 572

A multicentre validation study of the diagnostic value of plasma neurofilament light.

Ashton, N. J., Janelidze, S., Al Khleifat, A., Leuzy, A., van der Ende, E. L., Karikari, T. K., Benedet, A. L., Pascoal, T. A., Lleó, A., Parnetti, L., et al. (2021) · Nature Communications

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 545

Vagotomy and Parkinson disease: A Swedish register–based matched-cohort study

Liu, B., Fang, F., Pedersen, N. L., Tillander, A., Ludvigsson, J. F., Ekbom, A., Svenningsson, P., Chen, H., & Wirdefeldt, K. (2017) · Neurology

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 447

The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation

McEwen, B. S., Chattarji, S., Diamond, D. M., Jay, T. M., Reagan, L. P., Svenningsson, P., & Fuchs, E. (2010) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 406

Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

Keller, A., Westenberger, A., Sobrido, M. J., García-Murias, M., Domingo, A., Sears, R. L., Lemos, R. R., Ordoñez-Ugalde, A., Nicolas, G., da Cunha, J. E. G., et al. (2013) · Nature Genetics

Neurological diseases and metabolismNeurological and metabolic disorders

Cited by 324

How can drug discovery for psychiatric disorders be improved?

Agid, Y., Buzsáki, G., Diamond, D. M., Frackowiak, R., Giedd, J., Girault, J.-A., Grace, A., Lambert, J. J., Manji, H., Mayberg, H., et al. (2007) · Nature Reviews Drug Discovery

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 240

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

Bateup, H. S., Svenningsson, P., Kuroiwa, M., Gong, S., Nishi, A., Heintz, N., & Greengard, P. (2008) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 233

Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression

Melas, P. A., Rogdaki, M., Lennartsson, A., Björk, K., Qi, H., Witasp, A., Werme, M., Wegener, G., Mathé, A. A., Svenningsson, P., et al. (2012) · The International Journal of Neuropsychopharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 157

The Rho-Specific GEF Lfc Interacts with Neurabin and Spinophilin to Regulate Dendritic Spine Morphology

Ryan, X. P., Alldritt, J., Svenningsson, P., Allen, P. B., Wu, G.-Y., Nairn, A. C., & Greengard, P. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 142

Reversal of Depressed Behaviors in Mice by p11 Gene Therapy in the Nucleus Accumbens

Alexander, B., Warner-Schmidt, J., Eriksson, T. M., Tamminga, C., Arango-Lievano, M., Ghose, S., Vernov, M., Stavarache, M., Musatov, S., Flajolet, M., et al. (2010) · Science Translational Medicine

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 140

Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit

Yao, N., Skiteva, O., Zhang, X., Svenningsson, P., & Chergui, K. (2018) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 118

In vivo retention of 18 F-AV-1451 in corticobasal syndrome

Smith, R., Schöll, M., Widner, H., van Westen, D., Svenningsson, P., Hägerström, D., Ohlsson, T., Jögi, J., Nilsson, C., & Hansson, O. (2017) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 117

Neurogenic Effects of Fluoxetine Are Attenuated in p11 (S100A10) Knockout Mice

Egeland, M., Warner-Schmidt, J., Greengard, P., & Svenningsson, P. (2010) · Biological Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 94

Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

Bigio, B., Mathé, A. A., Sousa, V. C., Zelli, D., Svenningsson, P., McEwen, B. S., & Nasca, C. (2016) · Proceedings of the National Academy of Sciences

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 85

Ketamine decreases neuronally released glutamate via retrograde stimulation of presynaptic adenosine A1 receptors

Lazarevic, V., Yang, Y., Flais, I., & Svenningsson, P. (2021) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 81

A randomized placebo-controlled PET study of ketamine´s effect on serotonin1B receptor binding in patients with SSRI-resistant depression

Tiger, M., Veldman, E. R., Ekman, C.-J., Halldin, C., Svenningsson, P., & Lundberg, J. (2020) · Translational Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 81

Synaptic proteins in CSF relate to Parkinson’s disease stage markers

Bereczki, E., Bogstedt, A., Höglund, K., Tsitsi, P., Brodin, L., Ballard, C., Svenningsson, P., & Aarsland, D. (2017) · npj Parkinson's Disease

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 72

High Soluble Amyloid‐β42 Predicts Normal Cognition in Amyloid‐Positive Individuals With Alzheimer's Disease‐Causing Mutations

Sturchio, A., (DIAN), T. D. I. A. C., Dwivedi, A. K., Malm, T., Wood, M. J. A., Cilia, R., Sharma, J. S., Hill, E. J., Schneider, L. S., Graff-Radford, N. R., et al. (2022) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review)

Björkhem, I., Leoni, V., & Svenningsson, P. (2019) · The Journal of Steroid Biochemistry and Molecular Biology

Cholesterol and Lipid MetabolismBarrier Structure and Function Studies

Cited by 47

Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study

Brosseron, F., Kolbe, C., Santarelli, F., Carvalho, S., Antonell, A., Castro‐Gomez, S., Tacik, P., Namasivayam, A. A., Mangone, G., Schneider, R., et al. (2020) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 47

Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11

Eriksson, T. M., Alvarsson, A., Stan, T. L., Zhang, X., Hascup, K. N., Hascup, E. R., Kehr, J., Gerhardt, G. A., Warner-Schmidt, J., Arango-Lievano, M., et al. (2013) · Molecular Psychiatry

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 45

On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging

Kaya, I., Schembri, L. S., Nilsson, A., Shariatgorji, R., Baijnath, S., Zhang, X., Bezard, E., Svenningsson, P., Odell, L. R., & Andrén, P. E. (2023) · Journal of the American Society for Mass Spectrometry

Mass Spectrometry Techniques and ApplicationsMetabolomics and Mass Spectrometry Studies

Cited by 44

Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [ 11 C ] PBR28 and Machine Learning Analysis

Jucaite, A., Cselényi, Z., Kreisl, W. C., Rabiner, E. A., Varrone, A., Carson, R. E., Rinne, J. O., Savage, A., Schou, M., Johnström, P., et al. (2022) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 43