Gould, Todd D.

A Randomized Trial of the N-Methyl-d-Aspartate Receptor Glycine Site Antagonist Prodrug 4-Chlorokynurenine in Treatment-Resistant Depression

Park, L. T., Kadriu, B., Gould, T. D., Zanos, P., Greenstein, D., Evans, J. W., Yuan, P., Farmer, C. A., Oppenheimer, M., George, J. M., et al. (2020) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 63

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R )-hydroxynorketamine

Highland, J. N., Morris, P. J., Zanos, P., Lovett, J., Ghosh, S., Wang, A. Q., Zarate, C. A., Thomas, C. J., Moaddel, R., & Gould, T. D. (2019) · Journal of Psychopharmacology

Treatment of Major DepressionPharmacogenetics and Drug Metabolism

Cited by 62

DARPP-32: A molecular switch at the nexus of reward pathway plasticity

Gould, T. D., & Manji, H. K. (2005) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 56

Brain-based correlates of antidepressant response to ketamine: a comprehensive systematic review of neuroimaging studies

Medeiros, G. C., Matheson, M., Demo, I., Reid, M. J., Matheson, S., Twose, C., Smith, G. S., Gould, T. D., Zarate, C. A., Barrett, F. S., et al. (2023) · The Lancet Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 49

Targeting metaplasticity mechanisms to promote sustained antidepressant actions

Brown, K. A., & Gould, T. D. (2024) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 49

Intracellular Signaling Pathways Involved in ( S )- and ( R )-Ketamine Antidepressant Actions

Zanos, P., & Gould, T. D. (2018) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 42

Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit–Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice

Troppoli, T. A., Zanos, P., Georgiou, P., Gould, T. D., Rudolph, U., & Thompson, S. M. (2022) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 29

Ketamine Mechanism of Action: Separating the Wheat from the Chaff

Gould, T. D., Zanos, P., & Zarate, C. A. (2017) · Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 24

Treatment of depression with ketamine does not change plasma levels of brain-derived neurotrophic factor or vascular endothelial growth factor

Medeiros, G. C., Greenstein, D., Kadriu, B., Yuan, P., Park, L. T., Gould, T. D., & Zarate, C. A. (2021) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 24

Classical conditioning of antidepressant placebo effects in mice

Krimmel, S. R., Zanos, P., Georgiou, P., Colloca, L., & Gould, T. D. (2020) · Psychopharmacology

Pain Management and Placebo EffectTreatment of Major Depression

Cited by 12