Breen, Leigh

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

D’Hulst, G., Soro-Arnaiz, I., Masschelein, E., Veys, K., Fitzgerald, G., Smeuninx, B., Kim, S., Deldicque, L., Blaauw, B., Carmeliet, P., et al. (2020) · Nature Communications

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 2,310

Protein Ingestion to Stimulate Myofibrillar Protein Synthesis Requires Greater Relative Protein Intakes in Healthy Older Versus Younger Men

Moore, D. R., Churchward-Venne, T. A., Witard, O., Breen, L., Burd, N. A., Tipton, K. D., & Phillips, S. M. (2015) · The Journals of Gerontology: Series A

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 770

Resistance exercise load does not determine training-mediated hypertrophic gains in young men

Mitchell, C. J., Churchward-Venne, T. A., West, D. W. D., Burd, N. A., Breen, L., Baker, S. K., & Phillips, S. M. (2012) · Journal of Applied Physiology

Muscle metabolism and nutritionSports Performance and Training

Cited by 627

Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing

Breen, L., & Phillips, S. M. (2011) · Nutrition & Metabolism

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 576

Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise

Witard, O. C., Jackman, S. R., Breen, L., Smith, K., Selby, A., & Tipton, K. D. (2014) · The American Journal of Clinical Nutrition

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 517

Effects of leucine and its metabolite β‐hydroxy‐β‐methylbutyrate on human skeletal muscle protein metabolism

Wilkinson, D. J., Hossain, T., Hill, D. S., Phillips, B. E., Crossland, H., Williams, J., Loughna, P., Churchward‐Venne, T. A., Breen, L., Phillips, S. M., et al. (2013) · The Journal of Physiology

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 484

Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men

Yang, Y., Breen, L., Burd, N. A., Hector, A. J., Churchward-Venne, T. A., Josse, A. R., Tarnopolsky, M. A., & Phillips, S. M. (2012) · British Journal of Nutrition

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 480

Two Weeks of Reduced Activity Decreases Leg Lean Mass and Induces “Anabolic Resistance” of Myofibrillar Protein Synthesis in Healthy Elderly

Breen, L., Stokes, K. A., Churchward-Venne, T. A., Moore, D. R., Baker, S. K., Smith, K., Atherton, P. J., & Phillips, S. M. (2013) · The Journal of Clinical Endocrinology & Metabolism

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 395

Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: A double-blind, randomized trial

Churchward-Venne, T. A., Breen, L., Di Donato, D. M., Hector, A. J., Mitchell, C. J., Moore, D. R., Stellingwerff, T., Breuille, D., Offord, E. A., Baker, S. K., et al. (2014) · The American Journal of Clinical Nutrition

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 290

Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men

Yang, Y., Churchward-Venne, T. A., Burd, N. A., Breen, L., Tarnopolsky, M. A., & Phillips, S. M. (2012) · Nutrition & Metabolism

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 286

Live strong and prosper: the importance of skeletal muscle strength for healthy ageing

McLeod, M., Breen, L., Hamilton, D. L., & Philp, A. (2016) · Biogerontology

Nutrition and Health in AgingMuscle metabolism and nutrition

Cited by 274

The influence of carbohydrate–protein co‐ingestion following endurance exercise on myofibrillar and mitochondrial protein synthesis

Breen, L., Philp, A., Witard, O. C., Jackman, S. R., Selby, A., Smith, K., Baar, K., & Tipton, K. D. (2011) · The Journal of Physiology

Muscle metabolism and nutritionExercise and Physiological Responses

Cited by 143

Temporal changes in human skeletal muscle and blood lipid composition with fish oil supplementation

McGlory, C., Galloway, S. D. R., Hamilton, D. L., McClintock, C., Breen, L., Dick, J. R., Bell, J. G., & Tipton, K. D. (2014) · Prostaglandins Leukotrienes and Essential Fatty Acids

Fatty Acid Research and HealthMuscle metabolism and nutrition

Cited by 130

Whey protein supplementation preserves postprandial myofibrillar protein synthesis during short-term energy restriction in overweight and obese adults

Hector, A. J., Marcotte, G. R., Churchward-Venne, T. A., Murphy, C. H., Breen, L., von Allmen, M., Baker, S. K., & Phillips, S. M. (2015) · The Journal of Nutrition

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 119

Age-Related Anabolic Resistance of Myofibrillar Protein Synthesis Is Exacerbated in Obese Inactive Individuals

Smeuninx, B., Mckendry, J., Wilson, D., Martin, U., & Breen, L. (2017) · The Journal of Clinical Endocrinology & Metabolism

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 118

Dose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men

Robinson, M. J., Burd, N. A., Breen, L., Rerecich, T., Yang, Y., Hector, A. J., Baker, S. K., & Phillips, S. M. (2013) · Applied Physiology, Nutrition, and Metabolism

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 109

Low-load resistance training during step-reduction attenuates declines in muscle mass and strength and enhances anabolic sensitivity in older men

Devries, M. C., Breen, L., Von Allmen, M., MacDonald, M. J., Moore, D. R., Offord, E. A., Horcajada, M.-N., Breuillé, D., & Phillips, S. M. (2015) · Physiological Reports

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 107

Activation of mTOR signalling in young and old human skeletal muscle in response to combined resistance exercise and whey protein ingestion

Farnfield, M. M., Breen, L., Carey, K. A., Garnham, A., & Cameron-Smith, D. (2012) · Applied Physiology, Nutrition, and Metabolism

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 89

No Effect of Carbohydrate-Protein on Cycling Performance and Indices of Recovery

BREEN, L., TIPTON, K. D., & JEUKENDRUP, A. E. (2010) · Medicine & Science in Sports & Exercise

Muscle metabolism and nutritionSports Performance and Training

Cited by 71

A focus on leucine in the nutritional regulation of human skeletal muscle metabolism in ageing, exercise and unloading states

Ely, I. A., Phillips, B. E., Smith, K., Wilkinson, D. J., Piasecki, M., Breen, L., Larsen, M. S., & Atherton, P. J. (2023) · Clinical Nutrition

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 64

The Role of the Locus Coeruleus in Corticotropin-Releasing Hormone and Stress-Induced Suppression of Pulsatile Luteinizing Hormone Secretion in the Female Rat

Mitchell, J. C., Li, X. F., Breen, L., Thalabard, J.-C., & O’Byrne, K. T. (2005) · Endocrinology

Hypothalamic control of reproductive hormonesStress Responses and Cortisol

Cited by 58

Short inter-set rest blunts resistance exercise-induced increases in myofibrillar protein synthesis and intracellular signalling in young males

McKendry, J., Pérez‐López, A., McLeod, M., Luo, D., Dent, J. R., Smeuninx, B., Yu, J., Taylor, A. E., Philp, A., & Breen, L. (2016) · Experimental Physiology

Muscle metabolism and nutritionSports Performance and Training

Cited by 54

Nutrient interaction for optimal protein anabolism in resistance exercise

Breen, L., & Phillips, S. M. (2012) · Current Opinion in Clinical Nutrition and Metabolic Care

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 45

The role of protein hydrolysates for exercise-induced skeletal muscle recovery and adaptation: a current perspective

Morgan, P. T., & Breen, L. (2021) · Nutrition & Metabolism

Muscle metabolism and nutritionProtein Hydrolysis and Bioactive Peptides

Cited by 44