Huber, Kimberly M.

The mGluR theory of fragile X mental retardation

Bear, M. F., Huber, K. M., & Warren, S. T. (2004) · Trends in Neurosciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,580

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Huber, K. M., Gallagher, S. M., Warren, S. T., & Bear, M. F. (2002) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,349

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

Lüscher, C., & Huber, K. M. (2010) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 627

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

Gibson, J. R., Bartley, A. F., Hays, S. A., & Huber, K. M. (2008) · Journal of Neurophysiology

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 529

Rapid Translation of Arc/Arg3.1 Selectively Mediates mGluR-Dependent LTD through Persistent Increases in AMPAR Endocytosis Rate

Waung, M. W., Pfeiffer, B. E., Nosyreva, E. D., Ronesi, J. A., & Huber, K. M. (2008) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 474

Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons

Liu, M.-L., Zang, T., Zou, Y., Chang, J. C., Gibson, J. R., Huber, K. M., & Zhang, C.-L. (2013) · Nature Communications

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 343

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

Tsai, N.-P., Wilkerson, J. R., Guo, W., Maksimova, M. A., DeMartino, G. N., Cowan, C. W., & Huber, K. M. (2012) · Cell

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 316

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

Ronesi, J. A., Collins, K. A., Hays, S. A., Tsai, N.-P., Guo, W., Birnbaum, S. G., Hu, J.-H., Worley, P. F., Gibson, J. R., & Huber, K. M. (2012) · Nature Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 251

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

Harrington, A. J., Raissi, A., Rajkovich, K., Berto, S., Kumar, J., Molinaro, G., Raduazzo, J., Guo, Y., Loerwald, K., Konopka, G., et al. (2016) · eLife

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 193

Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation

Pfeiffer, B. E., & Huber, K. M. (2007) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 189

Current advances in local protein synthesis and synaptic plasticity

Pfeiffer, B. E., & Huber, K. M. (2006) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchRNA and protein synthesis mechanisms

Cited by 168

Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism

Huber, K. M., Klann, E., Costa-Mattioli, M., & Zukin, R. S. (2015) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 167

Evidence for a Fragile X Mental Retardation Protein-Mediated Translational Switch in Metabotropic Glutamate Receptor-Triggered Arc Translation and Long-Term Depression

Niere, F., Wilkerson, J. R., & Huber, K. M. (2012) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 153

Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2

Pfeiffer, B. E., Zang, T., Wilkerson, J. R., Taniguchi, M., Maksimova, M. A., Smith, L. N., Cowan, C. W., & Huber, K. M. (2010) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 153

A mouse model of the human Fragile X syndrome I304N mutation

Zang, J. B., Nosyreva, E. D., Spencer, C. M., Volk, L. J., Musunuru, K., Zhong, R., Stone, E. F., Yuva-Paylor, L. A., Huber, K. M., Paylor, R., et al. (2009) · PLoS Genetics

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 138

Increased Expression of the PI3K Enhancer PIKE Mediates Deficits in Synaptic Plasticity and Behavior in Fragile X Syndrome

Gross, C., Chang, C.-W., Kelly, S. M., Bhattacharya, A., McBride, S. M. J., Danielson, S. W., Jiang, M. Q., Chan, C. B., Ye, K., Gibson, J. R., et al. (2015) · Cell Reports

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 117

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice

Ade, K. K., Wan, Y., Hamann, H. C., O’Hare, J. K., Guo, W., Quian, A., Kumar, S., Bhagat, S., Rodriguiz, R. M., Wetsel, W. C., et al. (2016) · Biological Psychiatry

Obsessive-Compulsive Spectrum DisordersNeuroscience and Neuropharmacology Research

Cited by 84

Differential Activity-Dependent, Homeostatic Plasticity of Two Neocortical Inhibitory Circuits

Bartley, A. F., Huang, Z. J., Huber, K. M., & Gibson, J. R. (2008) · Journal of Neurophysiology

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 72

Selective Role of the Catalytic PI3K Subunit p110β in Impaired Higher Order Cognition in Fragile X Syndrome

Gross, C., Raj, N., Molinaro, G., Allen, A. G., Whyte, A. J., Gibson, J. R., Huber, K. M., Gourley, S. L., & Bassell, G. J. (2015) · Cell Reports

Genetics and Neurodevelopmental DisordersPI3K/AKT/mTOR signaling in cancer

Cited by 71

Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling

Zhang, Z., Cao, M., Chang, C.-W., Wang, C., Shi, X., Zhan, X., Birnbaum, S. G., Bezprozvanny, I., Huber, K. M., & Wu, J. I. (2016) · Molecular and Cellular Biology

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 48

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity

Zang, T., Maksimova, M. A., Cowan, C. W., Bassel-Duby, R., Olson, E. N., & Huber, K. M. (2013) · Molecular and Cellular Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 31