Dekker, Job

An encyclopedia of mouse DNA elements (Mouse ENCODE)

Mouse ENCODE Consortium, Stamatoyannopoulos, J. A., Snyder, M., Hardison, R., Ren, B., Gingeras, T., Gilbert, D. M., Groudine, M., Bender, M., Kaul, R., et al. (2012) · Genome Biology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 446

Polycomb repressive Complex 1 generates discrete compacted domains that change during differentiation

Kundu, S., Ji, F., Sunwoo, H., Jain, G., Lee, J. T., Sadreyev, R. I., Dekker, J., & Kingston, R. E. (2017) · Molecular Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 333

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

Seitan, V. C., Faure, A. J., Zhan, Y., McCord, R. P., Lajoie, B. R., Ing-Simmons, E., Lenhard, B., Giorgetti, L., Heard, E., Fisher, A. G., et al. (2013) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 318

Long-Range Chromatin Interactions

Dekker, J., & Misteli, T. (2015) · Cold Spring Harbor Perspectives in Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 255

Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells

Barutcu, A. R., Lajoie, B. R., McCord, R. P., Tye, C. E., Hong, D., Messier, T. L., Browne, G., van Wijnen, A. J., Lian, J. B., Stein, J. L., et al. (2015) · Genome Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 250

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

Bradner, J. E., Mak, R., Tanguturi, S. K., Mazitschek, R., Haggarty, S. J., Ross, K., Chang, C. Y., Bosco, J., West, N., Morse, E., et al. (2010) · Proceedings of the National Academy of Sciences

Hemoglobinopathies and Related DisordersHistone Deacetylase Inhibitors Research

Cited by 211

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains

Oudelaar, A. M., Davies, J. O. J., Hanssen, L. L. P., Telenius, J. M., Schwessinger, R., Liu, Y., Brown, J. M., Downes, D. J., Chiariello, A. M., Bianco, S., et al. (2018) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 196

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

Ing-Simmons, E., Seitan, V. C., Faure, A. J., Flicek, P., Carroll, T., Dekker, J., Fisher, A. G., Lenhard, B., & Merkenschlager, M. (2015) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 167

Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming

Beagan, J. A., Gilgenast, T. G., Kim, J., Plona, Z., Norton, H. K., Hu, G., Hsu, S. C., Shields, E. J., Lyu, X., Apostolou, E., et al. (2016) · Cell Stem Cell

Pluripotent Stem Cells ResearchGenomics and Chromatin Dynamics

Cited by 134

Transcriptional Silencers in Drosophila Serve a Dual Role as Transcriptional Enhancers in Alternate Cellular Contexts

Gisselbrecht, S. S., Palagi, A., Kurland, J. V., Rogers, J. M., Ozadam, H., Zhan, Y., Dekker, J., & Bulyk, M. L. (2020) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 128

The chromosome folding problem and how cells solve it

Dekker, J., & Mirny, L. A. (2024) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 112

3C-based technologies to study the shape of the genome

de Laat, W., & Dekker, J. (2012) · Methods

Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities

Cited by 84

The little skate genome and the evolutionary emergence of wing-like fins

Marlétaz, F., de la Calle-Mustienes, E., Acemel, R. D., Paliou, C., Naranjo, S., Martínez-García, P. M., Cases, I., Sleight, V. A., Hirschberger, C., Marcet-Houben, M., et al. (2023) · Nature

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 71

Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma

McGeachie, M. J., Yates, K. P., Zhou, X., Guo, F., Sternberg, A. L., Van Natta, M. L., Wise, R. A., Szefler, S. J., Sharma, S., Kho, A. T., et al. (2016) · American Journal of Respiratory and Critical Care Medicine

Asthma and respiratory diseasesGenetic Associations and Epidemiology

Cited by 25