Erler, Janine T.

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009) · Cell

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

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Pre-metastatic niches: organ-specific homes for metastases

Peinado, H., Zhang, H., Matei, I. R., Costa-Silva, B., Hoshino, A., Rodrigues, G., Psaila, B., Kaplan, R. N., Bromberg, J. F., Kang, Y., et al. (2017) · Nature Reviews Cancer

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 1,889

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

Cox, T. R., & Erler, J. T. (2011) · Disease Models & Mechanisms

Cellular Mechanics and InteractionsTGF-β signaling in diseases

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Lysyl oxidase is essential for hypoxia-induced metastasis

Erler, J. T., Bennewith, K. L., Nicolau, M., Dornhöfer, N., Kong, C., Le, Q.-T., Chi, J.-T. A., Jeffrey, S. S., & Giaccia, A. J. (2006) · Nature

Cancer, Hypoxia, and MetabolismMechanisms of cancer metastasis

Cited by 1,309

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

Erler, J. T., Bennewith, K. L., Cox, T. R., Lang, G., Bird, D., Koong, A., Le, Q.-T., & Giaccia, A. J. (2009) · Cancer Cell

Cancer Cells and MetastasisImmune cells in cancer

Cited by 1,231

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

Cox, T. R., Bird, D., Baker, A.-M., Barker, H. E., Ho, M. W.-Y., Lang, G., & Erler, J. T. (2013) · Cancer Research

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 571

RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

Cox, T. R., Rumney, R. M. H., Schoof, E. M., Perryman, L., Høye, A. M., Agrawal, A., Bird, D., Latif, N. A., Forrest, H., Evans, H. R., et al. (2015) · Nature

Bone health and treatmentsCancer Cells and Metastasis

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Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

Erler, J. T., Cawthorne, C. J., Williams, K. J., Koritzinsky, M., Wouters, B. G., Wilson, C., Miller, C., Demonacos, C., Stratford, I. J., & Dive, C. (2004) · Molecular and Cellular Biology

Cell death mechanisms and regulationCancer, Hypoxia, and Metabolism

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Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

Madsen, C. D., Pedersen, J. T., Venning, F. A., Singh, L. B., Moeendarbary, E., Charras, G., Cox, T. R., Sahai, E., & Erler, J. T. (2015) · The EMBO Reports

Cancer Cells and MetastasisCancer, Hypoxia, and Metabolism

Cited by 157

Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1

Brown, L. M., Cowen, R. L., Debray, C., Eustace, A., Erler, J. T., Sheppard, F. C., Parker, C. A., Stratford, I. J., & Williams, K. J. (2006) · Molecular Pharmacology

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 125

Tumor-Secreted LOXL2 Activates Fibroblasts through FAK Signaling

Barker, H. E., Bird, D., Lang, G., & Erler, J. T. (2013) · Molecular Cancer Research

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 119

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

Graham, H. K., Hodson, N. W., Hoyland, J. A., Millward-Sadler, S. J., Garrod, D., Scothern, A., Griffiths, C. E. M., Watson, R. E. B., Cox, T. R., Erler, J. T., et al. (2010) · Matrix Biology

Force Microscopy Techniques and ApplicationsCellular Mechanics and Interactions

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Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

Mayorca-Guiliani, A. E., Willacy, O., Madsen, C. D., Rafaeva, M., Elisabeth Heumüller, S., Bock, F., Sengle, G., Koch, M., Imhof, T., Zaucke, F., et al. (2019) · Nature Protocols

Tissue Engineering and Regenerative Medicine3D Printing in Biomedical Research

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Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

Blache, U., Horton, E. R., Xia, T., Schoof, E. M., Blicher, L. H., Schönenberger, A., Snedeker, J. G., Martin, I., Erler, J. T., & Ehrbar, M. (2019) · Life Science Alliance

Mesenchymal stem cell researchCancer Cells and Metastasis

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