Tschumperlin, Daniel J.

Cellular senescence mediates fibrotic pulmonary disease

Schafer, M. J., White, T. A., Iijima, K., Haak, A. J., Ligresti, G., Atkinson, E. J., Oberg, A. L., Birch, J., Salmonowicz, H., Zhu, Y., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 1,613

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

Liu, F., Lagares, D., Choi, K. M., Stopfer, L., Marinković, A., Vrbanac, V., Probst, C. K., Hiemer, S. E., Sisson, T. H., Horowitz, J. C., et al. (2015) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Hippo pathway signaling and YAP/TAZInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 874

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice

Rahaman, S. O., Grove, L. M., Paruchuri, S., Southern, B. D., Abraham, S., Niese, K. A., Scheraga, R. G., Ghosh, S., Thodeti, C. K., Zhang, D. X., et al. (2014) · Journal of Clinical Investigation

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisIon Channels and Receptors

Cited by 310

Cell Elasticity Determines Macrophage Function

Patel, N. R., Bole, M., Chen, C., Hardin, C. C., Kho, A. T., Mih, J., Deng, L., Butler, J., Tschumperlin, D., Fredberg, J. J., et al. (2012) · PLoS ONE

Cellular Mechanics and InteractionsImmune cells in cancer

Cited by 275

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis

Lagares, D., Santos, A., Grasberger, P. E., Liu, F., Probst, C. K., Rahimi, R. A., Sakai, N., Kuehl, T., Ryan, J., Bhola, P., et al. (2017) · Science Translational Medicine

Systemic Sclerosis and Related DiseasesCell death mechanisms and regulation

Cited by 246

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

Dou, C., Liu, Z., Tu, K., Zhang, H., Chen, C., Yaqoob, U., Wang, Y., Wen, J., van Deursen, J., Sicard, D., et al. (2018) · Gastroenterology

Liver physiology and pathologyCellular Mechanics and Interactions

Cited by 240

Human airway organoid engineering as a step toward lung regeneration and disease modeling

Tan, Q., Choi, K. M., Sicard, D., & Tschumperlin, D. J. (2017) · Biomaterials

Tissue Engineering and Regenerative Medicine3D Printing in Biomedical Research

Cited by 191

Matrix biomechanics and dynamics in pulmonary fibrosis

Haak, A. J., Tan, Q., & Tschumperlin, D. J. (2018) · Matrix Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisCellular Mechanics and Interactions

Cited by 95

TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression

Jones, D. L., Haak, A. J., Caporarello, N., Choi, K. M., Ye, Z., Yan, H., Varelas, X., Ordog, T., Ligresti, G., & Tschumperlin, D. J. (2019) · Journal of Cell Science

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisHistone Deacetylase Inhibitors Research

Cited by 77

Liver sinusoidal endothelial cell expressed vascular cell adhesion molecule 1 promotes liver fibrosis

Guo, Q., Furuta, K., Islam, S., Caporarello, N., Kostallari, E., Dielis, K., Tschumperlin, D. J., Hirsova, P., & Ibrahim, S. H. (2022) · Frontiers in Immunology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 73

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

Haak, A., Kostallari, E., Sicard, D., Ligresti, G., Choi, K. M., Caporarello, N., Jones, D., Tan, Q., Meridew, J., Diaz Espinosa, A., et al. (2019) · Mechanisms of lung injury and repair

Hippo pathway signaling and YAP/TAZInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 11