Handa, Robert J.

Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

Oyola, M. G., & Handa, R. J. (2017) · Stress

Stress Responses and CortisolHypothalamic control of reproductive hormones

Cited by 710

Non-genomic actions of androgens

Foradori, C. D., Weiser, M. J., & Handa, R. J. (2008) · Frontiers in Neuroendocrinology

Estrogen and related hormone effectsSexual Differentiation and Disorders

Cited by 493

S-Equol, a potent ligand for estrogen receptor β, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora1–4,

Setchell, K. D., Clerici, C., Lephart, E. D., Cole, S. J., Heenan, C., Castellani, D., Wolfe, B. E., Nechemias-Zimmer, L., Brown, N. M., Lund, T. D., et al. (2005) · The American Journal of Clinical Nutrition

Phytoestrogen effects and researchPhytochemicals and Antioxidant Activities

Cited by 471

Chronic estrogen-induced alterations in adrenocorticotropin and corticosterone secretion, and glucocorticoid receptor-mediated functions in female rats

Burgess, L. H., & Handa, R. J. (1992) · Endocrinology

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 445

Novel Actions of Estrogen Receptor-β on Anxiety-Related Behaviors

Lund, T. D., Rovis, T., Chung, W. C. J., & Handa, R. J. (2005) · Endocrinology

Estrogen and related hormone effectsNeurotransmitter Receptor Influence on Behavior

Cited by 436

Gonadal steroid hormones and the hypothalamo–pituitary–adrenal axis

Handa, R. J., & Weiser, M. J. (2014) · Frontiers in Neuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 408

Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and foot shock stressors

Handa, R. J., Nunley, K. M., Lorens, S. A., Louie, J. P., McGivern, R. F., & Bollnow, M. R. (1994) · Physiology & Behavior

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 325

Estrogen impairs glucocorticoid dependent negative feedback on the hypothalamic–pituitary–adrenal axis via estrogen receptor alpha within the hypothalamus

Weiser, M. J., & Handa, R. J. (2009) · Neuroscience

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 250

The Androgen 5α-Dihydrotestosterone and Its Metabolite 5α-Androstan-3β, 17β-Diol Inhibit the Hypothalamo–Pituitary–Adrenal Response to Stress by Acting through Estrogen Receptor β-Expressing Neurons in the Hypothalamus

Lund, T. D., Hinds, L. R., & Handa, R. J. (2006) · The Journal of Neuroscience

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 236

An alternate pathway for androgen regulation of brain function: Activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5α-androstane-3β,17β-diol

Handa, R. J., Pak, T. R., Kudwa, A. E., Lund, T. D., & Hinds, L. (2008) · Hormones and Behavior

Estrogen and related hormone effectsStress Responses and Cortisol

Cited by 205

Influence of perinatal androgen on the sexually dimorphic distribution of tyrosine hydroxylase-immunoreactive cells and fibers in the anteroventral periventricular nucleus of the rat

Simerly, R. B., Swanson, L. W., Handa, R. J., & Gorski, R. A. (2008) · Neuroendocrinology

Sexual Differentiation and DisordersHypothalamic control of reproductive hormones

Cited by 188

Androgen Inhibits, While Oestrogen Enhances, Restraint‐Induced Activation of Neuropeptide Neurones in the Paraventricular Nucleus of the Hypothalamus

Lund, T. D., Munson, D. J., Haldy, M. E., & Handa, R. J. (2004) · Journal of Neuroendocrinology

Stress Responses and CortisolNeuroendocrine regulation and behavior

Cited by 172

Estrogen Receptors Modulation of Anxiety-Like Behavior

Borrow, A. P., & Handa, R. J. (2017) · Vitamins and Hormones

Estrogen and related hormone effectsNeuroendocrine regulation and behavior

Cited by 146

Estrogen Receptor-β Agonist Diarylpropionitrile: Biological Activities of R- and S-Enantiomers on Behavior and Hormonal Response to Stress

Weiser, M. J., Wu, T. J., & Handa, R. J. (2009) · Endocrinology

Estrogen and related hormone effectsEffects and risks of endocrine disrupting chemicals

Cited by 124

Anxiolytic Effects and Neuroanatomical Targets of Estrogen Receptor-β (ERβ) Activation by a Selective ERβ Agonist in Female Mice

Oyola, M. G., Portillo, W., Reyna, A., Foradori, C. D., Kudwa, A., Hinds, L., Handa, R. J., & Mani, S. K. (2012) · Endocrinology

Estrogen and related hormone effectsStress Responses and Cortisol

Cited by 99

Roles for Oestrogen Receptor β in Adult Brain Function

Handa, R. J., Ogawa, S., Wang, J. M., & Herbison, A. E. (2012) · Journal of Neuroendocrinology

Estrogen and related hormone effectsNeuroendocrine regulation and behavior

Cited by 97

Estrogen Receptor (ER)β Isoforms Rather Than ERα Regulate Corticotropin-Releasing Hormone Promoter Activity through an Alternate Pathway

Miller, W. J. S., Suzuki, S., Miller, L. K., Handa, R., & Uht, R. M. (2004) · The Journal of Neuroscience

Estrogen and related hormone effectsStress Responses and Cortisol

Cited by 97

A Splice Variant of Estrogen Receptor β Missing Exon 3 Displays Altered Subnuclear Localization and Capacity for Transcriptional Activation*

Price, R. H., Butler, C. A., Webb, P., Uht, R., Kushner, P., & Handa, R. J. (2001) · Endocrinology

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 76

Regulation of Estrogen Receptor-β Expression in the Female Rat Hypothalamus: Differential Effects of Dexamethasone and Estradiol

Suzuki, S., & Handa, R. J. (2004) · Endocrinology

Estrogen and related hormone effectsHypothalamic control of reproductive hormones

Cited by 74

Chronic variable stress alters hypothalamic–pituitary–adrenal axis function in the female mouse

Borrow, A. P., Heck, A. L., Miller, A. M., Sheng, J. A., Stover, S. A., Daniels, R. M., Bales, N. J., Fleury, T. K., & Handa, R. J. (2019) · Physiology & Behavior

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 68

Estrogen receptor beta activation prevents glucocorticoid receptor-dependent effects of the central nucleus of the amygdala on behavior and neuroendocrine function

Weiser, M. J., Foradori, C. D., & Handa, R. J. (2010) · Brain Research

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 66

Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats

Handa, R. J., Kudwa, A. E., Donner, N. C., McGivern, R. F., & Brown, R. (2013) · Brain Research

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 56

Distribution and chemical composition of estrogen receptor β neurons in the paraventricular nucleus of the female and male mouse hypothalamus

Oyola, M. G., Thompson, M. K., Handa, A. Z., & Handa, R. J. (2017) · Journal of Comparative Neurology

Stress Responses and CortisolNeuroendocrine regulation and behavior

Cited by 53

Sex-dependent associations of maternal androgen levels with offspring BMI and weight trajectory from birth to early childhood

Huang, G., Aroner, S. A., Bay, C. P., Gilman, S. E., Ghassabian, A., Loucks, E. B., Buka, S. L., Handa, R. J., Lasley, B. L., Bhasin, S., et al. (2021) · Journal of Endocrinological Investigation

Birth, Development, and HealthGestational Diabetes Research and Management

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