Arai, Hiroyuki

Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

Kishino, S., Takeuchi, M., Park, S.-B., Hirata, A., Kitamura, N., Kunisawa, J., Kiyono, H., Iwamoto, R., Isobe, Y., Arita, M., et al. (2013) · Proceedings of the National Academy of Sciences

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 395

Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?

Clark, C. M., Xie, S., Chittams, J., Ewbank, D., Peskind, E., Galasko, D., Morris, J. C., McKeel, D. W., Farlow, M., Weitlauf, S. L., et al. (2003) · Archives of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 357

Longitudinal study of cerebrospinal fluid levels of tau, Aβ1–40, and Aβ1–42(43) in Alzheimer's disease: A study in Japan

Kanai, M., Matsubara, E., Isoe, K., Urakami, K., Nakashima, K., Arai, H., Sasaki, H., Abe, K., Iwatsubo, T., Kosaka, T., et al. (1998) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 340

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease

Harada, R., Okamura, N., Furumoto, S., Furukawa, K., Ishiki, A., Tomita, N., Tago, T., Hiraoka, K., Watanuki, S., Shidahara, M., et al. (2016) · Journal of Nuclear Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 330

Delayed-onset ataxia in mice lacking α-tocopherol transfer protein: Model for neuronal degeneration caused by chronic oxidative stress

Yokota, T., Igarashi, K., Uchihara, T., Jishage, K.-I., Tomita, H., Inaba, A., Li, Y., Arita, M., Suzuki, H., Mizusawa, H., et al. (2001) · Proceedings of the National Academy of Sciences

Antioxidant Activity and Oxidative StressHereditary Neurological Disorders

Cited by 261

MicroRNAs in Plasma and Cerebrospinal Fluid as Potential Markers for Alzheimer's Disease

Kiko, T., Nakagawa, K., Tsuduki, T., Furukawa, K., Arai, H., & Miyazawa, T. (2014) · Journal of Alzheimer's Disease

MicroRNA in disease regulationDementia and Cognitive Impairment Research

Cited by 256

Large‐scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease

Itoh, N., Arai, H., Urakami, K., Ishiguro, K., Ohno, H., Hampel, H., Buerger, K., Wiltfang, J., Otto, M., Kretzschmar, H., et al. (2001) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 256

SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Miyashita, A., Koike, A., Jun, G., Wang, L.-S., Takahashi, S., Matsubara, E., Kawarabayashi, T., Shoji, M., Tomita, N., Arai, H., et al. (2013) · PLoS ONE

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 196

Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease

Harada, R., Ishiki, A., Kai, H., Sato, N., Furukawa, K., Furumoto, S., Tago, T., Tomita, N., Watanuki, S., Hiraoka, K., et al. (2018) · Journal of Nuclear Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 168

Glial fibrillar acidic protein in the cerebrospinal fluid of Alzheimer’s disease, dementia with Lewy bodies, and frontotemporal lobar degeneration

Ishiki, A., Kamada, M., Kawamura, Y., Terao, C., Shimoda, F., Tomita, N., Arai, H., & Furukawa, K. (2016) · Journal of Neurochemistry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 156

Neurotoxic Effects of Lipopolysaccharide on Nigral Dopaminergic Neurons Are Mediated by Microglial Activation, Interleukin-1β, and Expression of Caspase-11 in Mice

Arai, H., Furuya, T., Yasuda, T., Miura, M., Mizuno, Y., & Mochizuki, H. (2004) · Journal of Biological Chemistry

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 122

YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

Tanaka, H., Homma, H., Fujita, K., Kondo, K., Yamada, S., Jin, X., Waragai, M., Ohtomo, G., Iwata, A., Tagawa, K., et al. (2020) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 119

Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease

Wada, K., Arai, H., Takanashi, M., Fukae, J., Oizumi, H., Yasuda, T., Mizuno, Y., & Mochizuki, H. (2006) · NeuroReport

Parkinson's Disease Mechanisms and TreatmentsAngiogenesis and VEGF in Cancer

Cited by 109

Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis

Shibata, N., Arita, M., Misaki, Y., Dohmae, N., Takio, K., Ono, T., Inoue, K., & Arai, H. (2001) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismPlant biochemistry and biosynthesis

Cited by 108

Diagnostic significance of Tau protein in cerebrospinal fluid from patients with corticobasal degeneration or progressive supranuclear palsy

Urakami, K., Wada, K., Arai, H., Sasaki, H., Kanai, M., Shoji, M., Ishizu, H., Kashihara, K., Yamamoto, M., Tsuchiya-Ikemoto, K., et al. (2001) · Journal of the Neurological Sciences

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 97

Osh Proteins Control Nanoscale Lipid Organization Necessary for PI(4,5)P2 Synthesis

Nishimura, T., Gecht, M., Covino, R., Hummer, G., Surma, M. A., Klose, C., Arai, H., Kono, N., & Stefan, C. J. (2019) · Molecular Cell

Lipid Membrane Structure and BehaviorCellular transport and secretion

Cited by 56

Are food advanced glycation end products toxic in biological systems?

CHUYEN, N. V., ARAI, H., NAKANISHI, T., & UTSUNOMIYA, N. (2005) · Annals of the New York Academy of Sciences

Advanced Glycation End Products researchPotato Plant Research

Cited by 27