Knudsen, Karen E.

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

Mateo, J., Carreira, S., Sandhu, S., Miranda, S., Mossop, H., Perez-Lopez, R., Nava Rodrigues, D., Robinson, D., Omlin, A., Tunariu, N., et al. (2015) · New England Journal of Medicine

PARP inhibition in cancer therapyProstate Cancer Treatment and Research

Cited by 2,185

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Quigley, D. A., Dang, H. X., Zhao, S. G., Lloyd, P., Aggarwal, R., Alumkal, J. J., Foye, A., Kothari, V., Perry, M. D., Bailey, A. M., et al. (2018) · Cell

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

Cited by 733

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs

Londin, E., Loher, P., Telonis, A. G., Quann, K., Clark, P., Jing, Y., Hatzimichael, E., Kirino, Y., Honda, S., Lally, M., et al. (2015) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 404

Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer

Thangavel, C., Dean, J. L., Ertel, A., Knudsen, K. E., Aldaz, C. M., Witkiewicz, A. K., Clarke, R., & Knudsen, E. S. (2011) · Endocrine Related Cancer

Advanced Breast Cancer TherapiesEstrogen and related hormone effects

Cited by 302

The meaning of p16ink4aexpression in tumors: Functional significance, clinical associations and future developments

Witkiewicz, A. K., Knudsen, K. E., Dicker, A. P., & Knudsen, E. S. (2011) · Cell Cycle

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 286

Beyond DNA Repair: DNA-PK Function in Cancer

Goodwin, J. F., & Knudsen, K. E. (2014) · Cancer Discovery

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 258

Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors

Hovelson, D. H., McDaniel, A. S., Cani, A. K., Johnson, B., Rhodes, K., Williams, P. D., Bandla, S., Bien, G., Choppa, P., Hyland, F., et al. (2015) · Neoplasia

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 224

USP22 regulates oncogenic signaling pathways to drive lethal cancer progression

Schrecengost, R. S., Dean, J. L., Goodwin, J. F., Schiewer, M. J., Urban, M. W., Stanek, T. J., Sussman, R. T., Hicks, J. L., Birbe, R. C., Draganova-Tacheva, R. A., et al. (2014) · Cancer Research

Ubiquitin and proteasome pathwaysProstate Cancer Treatment and Research

Cited by 126

Disparities and Trends in Genitourinary Cancer Incidence and Mortality in the USA

Schafer, E. J., Jemal, A., Wiese, D., Sung, H., Kratzer, T. B., Islami, F., Dahut, W. L., & Knudsen, K. E. (2023) · European Urology

Global Cancer Incidence and ScreeningTesticular diseases and treatments

Cited by 114

The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)

Sussman, R. T., Stanek, T. J., Esteso, P., Gearhart, J. D., Knudsen, K. E., & McMahon, S. B. (2013) · Journal of Biological Chemistry

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 91

Response and Resistance to Paradox-Breaking BRAF Inhibitor in Melanomas In Vivo and Ex Vivo

Hartsough, E. J., Kugel, C. H., Vido, M. J., Berger, A. C., Purwin, T. J., Goldberg, A., Davies, M. A., Schiewer, M. J., Knudsen, K. E., Bollag, G., et al. (2018) · Molecular Cancer Therapeutics

Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations

Cited by 27

Consequence of the tumor-associated conversion to cyclin D1b

Augello, M. A., Berman‐Booty, L. D., Carr, R., Yoshida, A., Dean, J. L., Schiewer, M. J., Feng, F. Y., Tomlins, S. A., Gao, E., Koch, W. J., et al. (2015) · EMBO Molecular Medicine

Cancer-related Molecular PathwaysSignaling Pathways in Disease

Cited by 23