Klumperman, Judith

Termination of autophagy and reformation of lysosomes regulated by mTOR

Yu, L., McPhee, C. K., Zheng, L., Mardones, G. A., Rong, Y., Peng, J., Mi, N., Zhao, Y., Liu, Z., Wan, F., et al. (2010) · Nature

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 1,544

Trafficking and function of the tetraspanin CD63

Pols, M. S., & Klumperman, J. (2009) · Experimental Cell Research

Cellular transport and secretionCell Adhesion Molecules Research

Cited by 745

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

Dejanovic, B., Huntley, M. A., De Mazière, A., Meilandt, W. J., Wu, T., Srinivasan, K., Jiang, Z., Gandham, V., Friedman, B. A., Ngu, H., et al. (2018) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 517

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

DeSelm, C. J., Miller, B. C., Zou, W., Beatty, W. L., van Meel, E., Takahata, Y., Klumperman, J., Tooze, S. A., Teitelbaum, S. L., & Virgin, H. W. (2011) · Developmental Cell

Bone Metabolism and DiseasesAutophagy in Disease and Therapy

Cited by 487

Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models

Dejanovic, B., Wu, T., Tsai, M.-C., Graykowski, D., Gandham, V. D., Rose, C. M., Bakalarski, C. E., Ngu, H., Wang, Y., Pandey, S., et al. (2022) · Nature Aging

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 341

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

Nakamura, N., Lill, J. R., Phung, Q., Jiang, Z., Bakalarski, C., de Mazière, A., Klumperman, J., Schlatter, M., Delamarre, L., & Mellman, I. (2014) · Nature

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 313

Syntaxin 13 Mediates Cycling of Plasma Membrane Proteins via Tubulovesicular Recycling Endosomes

Prekeris, R., Klumperman, J., Chen, Y. A., & Scheller, R. H. (1998) · The Journal of Cell Biology

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 286

Sorting nexin 17 facilitates LRP recycling in the early endosome

van Kerkhof, P., Lee, J., McCormick, L., Tetrault, E., Lu, W., Schoenfish, M., Oorschot, V., Strous, G. J., Klumperman, J., & Bu, G. (2005) · The EMBO Journal

Cellular transport and secretionCholesterol and Lipid Metabolism

Cited by 148

α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes

Dilsizoglu Senol, A., Samarani, M., Syan, S., Guardia, C. M., Nonaka, T., Liv, N., Latour-Lambert, P., Hasegawa, M., Klumperman, J., Bonifacino, J. S., et al. (2021) · PLOS Biology

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 134

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

Mieulet, V., Roceri, M., Espeillac, C., Sotiropoulos, A., Ohanna, M., Oorschot, V., Klumperman, J., Sandri, M., & Pende, M. (2007) · American Journal of Physiology-Cell Physiology

PI3K/AKT/mTOR signaling in cancerMuscle Physiology and Disorders

Cited by 99

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

Peeters, J. G. C., Picavet, L. W., Coenen, S. G. J. M., Mauthe, M., Vervoort, S. J., Mocholi, E., de Heus, C., Klumperman, J., Vastert, S. J., Reggiori, F., et al. (2019) · Autophagy

Autophagy in Disease and TherapyGenomics and Chromatin Dynamics

Cited by 55

Presenilin‐1 Exists in Both Pre‐ and Post‐Golgi Compartments and Recycles Via COPI‐Coated Membranes

Réchards, M., Xia, W., Oorschot, V. M. J., Selkoe, D. J., & Klumperman, J. (2003) · Traffic

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 55

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance

Wijers, M., Zanoni, P., Liv, N., Vos, D. Y., Jäckstein, M. Y., Smit, M., Wilbrink, S., Wolters, J. C., van der Veen, Y. T., Huijkman, N., et al. (2019) · JCI Insight

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 44

HEPES Activates a MiT/TFE-dependent Lysosomal-Autophagic Gene Network in Cultured Cells: A Call for Caution

Tol, M. J., van der Lienden, M. J. C., Gabriel, T. L., Hagen, J. J., Scheij, S., Veenendaal, T., Klumperman, J., Donker-Koopman, W. E., Verhoeven, A. J., Overkleeft, H., et al. (2018) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 27

Mechanism and regulation of cargo entry into the Commander endosomal recycling pathway

Butkovič, R., Walker, A. P., Healy, M. D., McNally, K. E., Liu, M., Veenendaal, T., Kato, K., Liv, N., Klumperman, J., Collins, B. M., et al. (2024) · Nature Communications

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 26