Zannis, Vassilis I.

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

Zannis, V. I., & Breslow, J. L. (1981) · Biochemistry

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 563

Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes

Zannis, V. I., Breslow, J. L., Utermann, G., Mahley, R. W., Weisgraber, K. H., Havel, R. J., Goldstein, J. L., Brown, M. S., Schonfeld, G., Hazzard, W. R., et al. (1982) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthAlzheimer's disease research and treatments

Cited by 436

Studies of familial type III hyperlipoproteinemia using as a genetic marker the apoE phenotype E2/2

Breslow, J. L., Zannis, V. I., SanGiacomo, T. R., Third, J. L., Tracy, T., & Glueck, C. J. (1982) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 174

Interaction of Nascent ApoE2, ApoE3, and ApoE4 Isoforms Expressed in Mammalian Cells with Amyloid Peptide β (1−40). Relevance to Alzheimer's Disease

Aleshkov, S., Abraham, C. R., & Zannis, V. I. (1997) · Biochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 138

The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene.

Cladaras, C., Hadzopoulou-Cladaras, M., Felber, B. K., Pavlakis, G., & Zannis, V. I. (1987) · Journal of Biological Chemistry

RNA Research and SplicingLipid metabolism and disorders

Cited by 92

Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT

Kypreos, K. E., & Zannis, V. I. (2007) · Biochemical Journal

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 90

Genetic Mutations Affecting Human Lipoproteins, Their Receptors, and Their Enzymes

Zannis, V. I., Kardassis, D., & Zanni, E. E. (1993) · Advances in Human Genetics 21

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 78

Probing the pathways of chylomicron and HDL metabolism using adenovirus-mediated gene transfer

Zannis, V. I., Chroni, A., Kypreos, K. E., Kan, H.-Y., Cesar, T. B., Zanni, E. E., & Kardassis, D. (2004) · Current Opinion in Lipidology

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 74

Genetic Mutations Affecting Human Lipoprotein Metabolism

Zannis, V. I., & Breslow, J. L. (1985) · Advances in Human Genetics 14

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 65

Domains of Apolipoprotein E Contributing to Triglyceride and Cholesterol Homeostasis in Vivo

Kypreos, K. E., van Dijk, K. W., van der Zee, A., Havekes, L. M., & Zannis, V. I. (2001) · Journal of Biological Chemistry

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 62

LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mice

Kypreos, K. E., & Zannis, V. I. (2006) · Journal of Lipid Research

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 45

An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42

Dafnis, I., Stratikos, E., Tzinia, A., Tsilibary, E. C., Zannis, V. I., & Chroni, A. (2010) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 41

LCAT can Rescue the Abnormal Phenotype Produced by the Natural ApoA-I Mutations (Leu141Arg)Pisa and (Leu159Arg)FIN

Koukos, G., Chroni, A., Duka, A., Kardassis, D., & Zannis, V. I. (2007) · Biochemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 33

An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines

Dafnis, I., Tzinia, A. K., Tsilibary, E. C., Zannis, V. I., & Chroni, A. (2012) · Neuroscience

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 32

A dominant negative form of the transcription factor c-Jun affects genes that have opposing effects on lipid homeostasis in mice

Drosatos, K., Sanoudou, D., Kypreos, K. E., Kardassis, D., & Zannis, V. I. (2007) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 26

Biophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties.

Chroni, A., Pyrpassopoulos, S., Thanassoulas, A., Nounesis, G., Zannis, V. I., & Stratikos, E. (2008) · Biochemistry

Protein Structure and DynamicsAlzheimer's disease research and treatments

Cited by 26

Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia

Georgiadou, D., Chroni, A., Vezeridis, A., Zannis, V. I., & Stratikos, E. (2011) · PLoS ONE

Protein Structure and DynamicsLipid Membrane Structure and Behavior

Cited by 24

mRNA and apolipoprotein E synthesis abnormalities in peripheral blood monocyte macrophages in familial apolipoprotein E deficiency.

Zannis, V. I., Ordovas, J. M., Cladaras, C., Cole, F. S., Forbes, G., & Schaefer, E. J. (1985) · Journal of Biological Chemistry

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 21

Molecular etiology of a dominant form of type III hyperlipoproteinemia caused by R142C substitution in apoE4

Vezeridis, A. M., Drosatos, K., & Zannis, V. I. (2011) · Journal of Lipid Research

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 11

apoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL

Fotakis, P., Vezeridis, A., Dafnis, I., Chroni, A., Kardassis, D., & Zannis, V. I. (2014) · Journal of Lipid Research

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 4