Eilers, Martin

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A.-P., et al. (2002) · Cell

Wnt/β-catenin signaling in development and cancerGenetic factors in colorectal cancer

Cited by 2,030

MYC regulates the antitumor immune response through CD47 and PD-L1

Casey, S. C., Tong, L., Li, Y., Do, R., Walz, S., Fitzgerald, K. N., Gouw, A. M., Baylot, V., Gütgemann, I., Eilers, M., et al. (2016) · Science

Cancer Immunotherapy and BiomarkersPhagocytosis and Immune Regulation

Cited by 1,403

Myc’s broad reach

Eilers, M., & Eisenman, R. N. (2008) · Genes & Development

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 927

Target gene-independent functions of MYC oncoproteins

Baluapuri, A., Wolf, E., & Eilers, M. (2020) · Nature Reviews Molecular Cell Biology

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 310

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Rudalska, R., Dauch, D., Longerich, T., McJunkin, K., Wuestefeld, T., Kang, T.-W., Hohmeyer, A., Pesic, M., Leibold, J., von Thun, A., et al. (2014) · Nature Medicine

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and Studies

Cited by 282

MYC and tumor metabolism: chicken and egg

Dejure, F. R., & Eilers, M. (2017) · The EMBO Journal

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 240

Contributions of Myc to tumorigenesis

Lutz, W., Leon, J., & Eilers, M. (2002) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 177

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

Baluapuri, A., Hofstetter, J., Dudvarski Stankovic, N., Endres, T., Bhandare, P., Vos, S. M., Adhikari, B., Schwarz, J. D., Narain, A., Vogt, M., et al. (2019) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 138

Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1

Gebhardt, A., Frye, M., Herold, S., Benitah, S. A., Braun, K., Samans, B., Watt, F. M., Elsässer, H.-P., & Eilers, M. (2006) · The Journal of Cell Biology

Skin and Cellular Biology ResearchCell Adhesion Molecules Research

Cited by 118

DNA Binding Cooperativity of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis

Schlereth, K., Beinoraviciute-Kellner, R., Zeitlinger, M. K., Bretz, A. C., Sauer, M., Charles, J. P., Vogiatzi, F., Leich, E., Samans, B., Eilers, M., et al. (2010) · Molecular Cell

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 113

OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors

Jung, L. A., Gebhardt, A., Koelmel, W., Ade, C. P., Walz, S., Kuper, J., von Eyss, B., Letschert, S., Redel, C., d'Artista, L., et al. (2017) · Oncogene

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 101

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Alborzinia, H., Chen, Z., Yildiz, U., Freitas, F. P., Vogel, F. C. E., Varga, J. P., Batani, J., Bartenhagen, C., Schmitz, W., Büchel, G., et al. (2023) · EMBO Molecular Medicine

Ferroptosis and cancer prognosisNeuroblastoma Research and Treatments

Cited by 85

Selective Ablation of Retinoblastoma Protein Function by the RET Finger Protein

Krützfeldt, M., Ellis, M., Weekes, D. B., Bull, J. J., Eilers, M., Vivanco, M. D. M., Sellers, W. R., & Mittnacht, S. (2005) · Molecular Cell

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 48

USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

Reissland, M., Hartmann, O., Tauch, S., Bugter, J. M., Prieto-Garcia, C., Schulte, C., Loebbert, S., Solvie, D., Bitman-Lotan, E., Narain, A., et al. (2024) · Oncogene

Wnt/β-catenin signaling in development and cancerUbiquitin and proteasome pathways

Cited by 16