Moses, Harold L.

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

Özdemir, B. C., Pentcheva-Hoang, T., Carstens, J. L., Zheng, X., Wu, C.-C., Simpson, T. R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S. V., et al. (2014) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 2,681

TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

Bhowmick, N. A., Chytil, A., Plieth, D., Gorska, A. E., Dumont, N., Shappell, S., Washington, M. K., Neilson, E. G., & Moses, H. L. (2004) · Science

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 1,401

TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression

Yang, L., Pang, Y., & Moses, H. L. (2010) · Trends in Immunology

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 1,023

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

Yang, L., Huang, J., Ren, X., Gorska, A. E., Chytil, A., Aakre, M., Carbone, D. P., Matrisian, L. M., Richmond, A., Lin, P. C., et al. (2008) · Cancer Cell

TGF-β signaling in diseasesImmune cells in cancer

Cited by 918

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

Postlethwaite, A. E., Keski-Oja, J., Moses, H. L., & Kang, A. H. (1987) · The Journal of experimental medicine

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 777

Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

Yang, E. Y., & Moses, H. L. (1990) · The Journal of cell biology

TGF-β signaling in diseasesAngiogenesis and VEGF in Cancer

Cited by 464

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

Sato, Y., Tsuboi, R., Lyons, R., Moses, H., & Rifkin, D. B. (1990) · The Journal of cell biology

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 444

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-β signaling in cooperation with active Kras expression

Ijichi, H., Chytil, A., Gorska, A. E., Aakre, M. E., Fujitani, Y., Fujitani, S., Wright, C. V. E., & Moses, H. L. (2006) · Genes & Development

Pancreatic and Hepatic Oncology ResearchTGF-β signaling in diseases

Cited by 379

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

Ijichi, H., Chytil, A., Gorska, A. E., Aakre, M. E., Bierie, B., Tada, M., Mohri, D., Miyabayashi, K., Asaoka, Y., Maeda, S., et al. (2011) · Journal of Clinical Investigation

Pancreatic and Hepatic Oncology ResearchChemokine receptors and signaling

Cited by 256

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

Özdemir, B. C., Pentcheva-Hoang, T., Carstens, J. L., Zheng, X., Wu, C.-C., Simpson, T. R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S. V., et al. (2015) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchTGF-β signaling in diseases

Cited by 245

Transforming Growth Factor β: Tumor Suppressor or Promoter? Are Host Immune Cells the Answer?

Yang, L., & Moses, H. L. (2008) · Cancer Research

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 151

PI3K inhibition reduces mammary tumor growth and facilitates antitumor immunity and anti-PD1 responses

Sai, J., Owens, P., Novitskiy, S. V., Hawkins, O. E., Vilgelm, A. E., Yang, J., Sobolik, T., Lavender, N., Johnson, A. C., McClain, C., et al. (2017) · Clinical Cancer Research

PI3K/AKT/mTOR signaling in cancerCancer Immunotherapy and Biomarkers

Cited by 138

Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties

Novitskiy, S. V., Pickup, M. W., Chytil, A., Polosukhina, D., Owens, P., & Moses, H. L. (2012) · Journal of Leukocyte Biology

Immune cells in cancerTGF-β signaling in diseases

Cited by 79