Ginhoux, Florent

Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

Cheng, Y., Gunasegaran, B., Singh, H. D., Dutertre, C.-A., Loh, C. Y., Lim, J. Q., Crawford, J. C., Lee, H. K., Zhang, X., Lee, B., et al. (2021) · Immunity

Cancer Immunotherapy and BiomarkersHepatitis B Virus Studies

Cited by 142

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

Chong, S. Z., Evrard, M., Devi, S., Chen, J., Lim, J. Y., See, P., Zhang, Y., Adrover, J. M., Lee, B., Tan, L., et al. (2016) · Journal of Experimental Medicine

Chemokine receptors and signalingImmune cells in cancer

Cited by 142

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

Amorim, A., De Feo, D., Friebel, E., Ingelfinger, F., Anderfuhren, C. D., Krishnarajah, S., Andreadou, M., Welsh, C. A., Liu, Z., Ginhoux, F., et al. (2022) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancer

Cited by 140

Brain macrophage development, diversity and dysregulation in health and disease

Silvin, A., Qian, J., & Ginhoux, F. (2023) · Cellular & Molecular Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 137

Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers

Li, L., Cui, L., Lin, P., Liu, Z., Bao, S., Ma, X., Nan, H., Zhu, W., Cen, J., Mao, Y., et al. (2023) · Cell Stem Cell

Liver physiology and pathologyMesenchymal stem cell research

Cited by 134

Targeting innate immunity for neurodegenerative disorders of the central nervous system

Andreasson, K. I., Bachstetter, A. D., Colonna, M., Ginhoux, F., Holmes, C., Lamb, B., Landreth, G., Lee, D. C., Low, D., Lynch, M. A., et al. (2016) · Journal of Neurochemistry

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 126

Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver

Peiseler, M., Araujo David, B., Zindel, J., Surewaard, B. G. J., Lee, W.-Y., Heymann, F., Nusse, Y., Castanheira, F. V. S., Shim, R., Guillot, A., et al. (2023) · Science

Liver physiology and pathologyImmune cells in cancer

Cited by 123

MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation

Vanneste, D., Bai, Q., Hasan, S., Peng, W., Pirottin, D., Schyns, J., Maréchal, P., Ruscitti, C., Meunier, M., Liu, Z., et al. (2023) · Nature Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 111

Notch signaling regulates macrophage-mediated inflammation in metabolic dysfunction-associated steatotic liver disease

Guo, W., Li, Z., Anagnostopoulos, G., Kong, W. T., Zhang, S., Chakarov, S., Shin, A., Qian, J., Zhu, Y., Bai, W., et al. (2024) · Immunity

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 109

Understanding the heterogeneity of resident liver macrophages

Blériot, C., & Ginhoux, F. (2019) · Frontiers in Immunology

Liver physiology and pathologyImmune cells in cancer

Cited by 107

Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes

Alraies, Z., Rivera, C. A., Delgado, M.-G., Sanséau, D., Maurin, M., Amadio, R., Maria Piperno, G., Dunsmore, G., Yatim, A., Lacerda Mariano, L., et al. (2024) · Nature Immunology

Cellular Mechanics and InteractionsImmunotherapy and Immune Responses

Cited by 106

Escherichia coli –Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer

Goubet, A.-G., Lordello, L., Alves Costa Silva, C., Peguillet, I., Gazzano, M., Mbogning-Fonkou, M. D., Thelemaque, C., Lebacle, C., Thibault, C., Audenet, F., et al. (2022) · Cancer Discovery

Cancer Immunotherapy and BiomarkersBladder and Urothelial Cancer Treatments

Cited by 86

Immune system and intestinal microbiota determine efficacy of androgen deprivation therapy against prostate cancer

Terrisse, S., Goubet, A.-G., Ueda, K., Thomas, A. M., Quiniou, V., Thelemaque, C., Dunsmore, G., Clave, E., Gamat-Huber, M., Yonekura, S., et al. (2022) · Journal for ImmunoTherapy of Cancer

Prostate Cancer Treatment and ResearchGut microbiota and health

Cited by 80

Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease

Tan-Garcia, A., Wai, L.-E., Zheng, D., Ceccarello, E., Jo, J., Banu, N., Khakpoor, A., Chia, A., Tham, C. Y. L., Tan, A. T., et al. (2017) · Journal of Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 68

Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders

Wilk, C. M., Cathomas, F., Török, O., Le Berichel, J., Park, M. D., Bigenwald, C., Heaton, G. R., Hamon, P., Troncoso, L., Scull, B. P., et al. (2023) · Immunity

Histiocytic Disorders and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 51

HLA-A*0201-restricted cytolytic responses to the rtTA transactivator dominant and cryptic epitopes compromise transgene expression induced by the tetracycline on system

Ginhoux, F., Turbant, S., Gross, D. A., Poupiot, J., Marais, T., Lone, Y., Lemonnier, F. A., Firat, H., Perez, N., Danos, O., et al. (2004) · Molecular Therapy

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 49

Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice

Kim, J.-S., Trzebanski, S., Shin, S.-H., Schori, L., Frumer Friedman, G. R., Ilani, N. C., Kadam, A., Vicario, R., Aust, O., Bugaeva, P., et al. (2025) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsAcute Myeloid Leukemia Research

Cited by 33

Recent advances in models of immune-mediated drug-induced liver injury

Tasnim, F., Huang, X., Lee, C. Z. W., Ginhoux, F., & Yu, H. (2021) · Frontiers in Toxicology

Drug-Induced Hepatotoxicity and ProtectionImmunotoxicology and immune responses

Cited by 32

Kupffer cell reverse migration into the liver sinusoids mitigates neonatal sepsis and meningitis

Araujo David, B., Atif, J., Vargas e Silva Castanheira, F., Yasmin, T., Guillot, A., Ait Ahmed, Y., Peiseler, M., Hommes, J. W., Salm, L., Brundler, M.-A., et al. (2024) · Science Immunology

Neonatal and Maternal InfectionsImmune cells in cancer

Cited by 25

Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin

Bhattacharjee, O., Ayyangar, U., Kurbet, A. S., Lakshmanan, V., Palakodeti, D., Ginhoux, F., & Raghavan, S. (2021) · Frontiers in Immunology

Immune cells in cancerWound Healing and Treatments

Cited by 14