Ginhoux, Florent

Macrophages in health and disease

Park, M. D., Silvin, A., Ginhoux, F., & Merad, M. (2022) · Cell

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 644

Stroma-derived interleukin-34 controls the development and maintenance of Langerhans cells and the maintenance of microglia

Greter, M., Lelios, I., Pelczar, P., Hoeffel, G., Price, J., Leboeuf, M., Kündig, T. M., Frei, K., Ginhoux, F., Merad, M., et al. (2012) · Immunity

Neuroinflammation and Neurodegeneration MechanismsCytokine Signaling Pathways and Interactions

Cited by 630

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology

T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Cited by 531

Determinants of resident tissue macrophage identity and function

Blériot, C., Chakarov, S., & Ginhoux, F. (2020) · Immunity

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 507

Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

Geirsdottir, L., David, E., Keren-Shaul, H., Weiner, A., Bohlen, S. C., Neuber, J., Balic, A., Giladi, A., Sheban, F., Dutertre, C.-A., et al. (2019) · Cell

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 461

Origin of microglia: current concepts and past controversies

Ginhoux, F., & Prinz, M. (2015) · Cold Spring Harbor Perspectives in Biology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 446

Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration

O’Koren, E. G., Yu, C., Klingeborn, M., Wong, A. Y. W., Prigge, C. L., Mathew, R., Kalnitsky, J., Msallam, R. A., Silvin, A., Kay, J. N., et al. (2019) · Immunity

Neuroinflammation and Neurodegeneration MechanismsRetinal Development and Disorders

Cited by 440

Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development

Utz, S. G., See, P., Mildenberger, W., Thion, M. S., Silvin, A., Lutz, M., Ingelfinger, F., Rayan, N. A., Lelios, I., Buttgereit, A., et al. (2020) · Cell

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 436

Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare

Chng, K. R., Tay, A. S. L., Li, C., Ng, A. H. Q., Wang, J., Suri, B. K., Matta, S. A., McGovern, N., Janela, B., Wong, X. F. C. C., et al. (2016) · Nature Microbiology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 388

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

Lim, H. Y., Lim, S. Y., Tan, C. K., Thiam, C. H., Goh, C. C., Carbajo, D., Chew, S. H. S., See, P., Chakarov, S., Wang, X. N., et al. (2018) · Immunity

Proteoglycans and glycosaminoglycans researchAtherosclerosis and Cardiovascular Diseases

Cited by 384

Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration

Silvin, A., Uderhardt, S., Piot, C., Da Mesquita, S., Yang, K., Geirsdottir, L., Mulder, K., Eyal, D., Liu, Z., Bridlance, C., et al. (2022) · Immunity

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 368

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

Giladi, A., Paul, F., Herzog, Y., Lubling, Y., Weiner, A., Yofe, I., Jaitin, D., Cabezas-Wallscheid, N., Dress, R., Ginhoux, F., et al. (2018) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 366

Ontogeny of Tissue-Resident Macrophages

Hoeffel, G., & Ginhoux, F. (2015) · Frontiers in Immunology

Immune cells in cancerHematopoietic Stem Cell Transplantation

Cited by 364

Human dermal CD14(+) cells are a transient population of monocyte-derived macrophages

McGovern, N., Schlitzer, A., Gunawan, M., Jardine, L., Shin, A., Poyner, E., Green, K., Dickinson, R., Wang, X.-N., Low, D., et al. (2014) · Immunity

Immunotherapy and Immune ResponsesImmune cells in cancer

Cited by 281

A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers

Fidelle, M., Rauber, C., Alves Costa Silva, C., Tian, A.-L., Lahmar, I., de La Varende, A.-L. M., Zhao, L., Thelemaque, C., Lebhar, I., Messaoudene, M., et al. (2023) · Science

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 243

A subset of Kupffer cells regulates metabolism through the expression of CD36

Blériot, C., Barreby, E., Dunsmore, G., Ballaire, R., Chakarov, S., Ficht, X., De Simone, G., Andreata, F., Fumagalli, V., Guo, W., et al. (2021) · Immunity

Immune cells in cancerLiver physiology and pathology

Cited by 236

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

Bénéchet, A. P., De Simone, G., Di Lucia, P., Cilenti, F., Barbiera, G., Le Bert, N., Fumagalli, V., Lusito, E., Moalli, F., Bianchessi, V., et al. (2019) · Nature

Hepatitis B Virus StudiesT-cell and B-cell Immunology

Cited by 222

CSF‐1 Controls Cerebellar Microglia and Is Required for Motor Function and Social Interaction

Kana, V., Desland, F. A., Casanova-Acebes, M., Ayata, P., Badimon, A., Nabel, E., Yamamuro, K., Sneeboer, M., Tan, I.-L., Flanigan, M. E., et al. (2019) · Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 220

DISCO: A database of Deeply Integrated human Single-Cell Omics data

Li, M., Zhang, X., Ang, K. S., Ling, J., Sethi, R., Lee, N. Y. S., Ginhoux, F., & Chen, J. (2022) · Nucleic Acids Research

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 205

Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems

Waisman, A., Ginhoux, F., Greter, M., & Bruttger, J. (2015) · Trends in Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 183

Single-cell analyses implicate ascites in remodeling the ecosystems of primary and metastatic tumors in ovarian cancer

Zheng, X., Wang, X., Cheng, X., Liu, Z., Yin, Y., Li, X., Huang, Z., Wang, Z., Guo, W., Ginhoux, F., et al. (2023) · Nature Cancer

Ovarian cancer diagnosis and treatmentSingle-cell and spatial transcriptomics

Cited by 172

Repositioning TH cell polarization from single cytokines to complex help

Tuzlak, S., Dejean, A. S., Iannacone, M., Quintana, F. J., Waisman, A., Ginhoux, F., Korn, T., & Becher, B. (2021) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 171

Dendritic Cell Regulation of Carbon Tetrachloride–Induced Murine Liver Fibrosis Regression

Jiao, J., Sastre, D., Fiel, M. I., Lee, U. E., Ghiassi–Nejad, Z., Ginhoux, F., Vivier, E., Friedman, S. L., Merad, M., & Aloman, C. (2012) · Hepatology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 154

Brain microvessel cross‐presentation is a hallmark of experimental cerebral malaria

Howland, S. W., Poh, C. M., Gun, S. Y., Claser, C., Malleret, B., Shastri, N., Ginhoux, F., Grotenbreg, G. M., & Rénia, L. (2013) · EMBO Molecular Medicine

Malaria Research and ControlBacterial Infections and Vaccines

Cited by 150