Hagopian, William

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

Herold, K. C., Hagopian, W., Auger, J. A., Poumian-Ruiz, E., Taylor, L., Donaldson, D., Gitelman, S. E., Harlan, D. M., Xu, D., Zivin, R. A., et al. (2002) · New England Journal of Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 1,222

Teplizumab for treatment of type 1 diabetes (Protege study): 1-year results from a randomised, placebo-controlled trial

Sherry, N., Hagopian, W., Ludvigsson, J., Jain, S. M., Wahlen, J., Ferry, R. J., Bode, B., Aronoff, S., Holland, C., Carlin, D., et al. (2011) · The Lancet

Diabetes and associated disordersDiabetes Management and Research

Cited by 493

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

the TEDDY Study Group, Krischer, J. P., Lynch, K. F., Schatz, D. A., Ilonen, J., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J.-X., Simell, O. G., et al. (2015) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 444

A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM

Grubin, C. E., Daniels, T., Toivola, B., Landin-Olsson, M., Hagopian, W. A., Li, L., Karlsen, A. E., Boel, E., Michelsen, B., & Lernmark, �. (1994) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 415

Development and standardization of an improved type 1 diabetes genetic risk score for use in newborn screening and incident diagnosis

Sharp, S. A., Rich, S. S., Wood, A. R., Jones, S. E., Beaumont, R. N., Harrison, J. W., Schneider, D. A., Locke, J. M., Tyrrell, J., Weedon, M. N., et al. (2019) · Diabetes Care

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 366

The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants

Hagopian, W. A., Erlich, H., Lernmark, Å., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Vogt, R., Blair, A., Ilonen, J., et al. (2011) · Pediatric Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 260

Frequency, Immunogenetics, and Clinical Characteristics of Latent Autoimmune Diabetes in China (LADA China Study)

Zhou, Z., Xiang, Y., Ji, L., Jia, W., Ning, G., Huang, G., Yang, L., Lin, J., Liu, Z., Hagopian, W. A., et al. (2013) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 251

Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes

Hagopian, W., Ferry, R. J., Sherry, N., Carlin, D., Bonvini, E., Johnson, S., Stein, K. E., Koenig, S., Daifotis, A. G., Herold, K. C., et al. (2013) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 247

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

Graham, J., Hagopian, W. A., Kockum, I., Li, L. S., Sanjeevi, C. B., Lowe, R. M., Schaefer, J. B., Zarghami, M., Day, H. L., Landin-Olsson, M., et al. (2002) · Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 230

Treatment of patients with new onset type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years

Herold, K. C., Gitelman, S., Greenbaum, C., Puck, J., Hagopian, W., Gottlieb, P., Sayre, P., Bianchine, P., Wong, E., Seyfert-Margolis, V., et al. (2009) · Clinical Immunology

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 219

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled, phase 2 trial

von Herrath, M., Bain, S. C., Bode, B., Clausen, J. O., Coppieters, K., Gaysina, L., Gumprecht, J., Hansen, T. K., Mathieu, C., Morales, C., et al. (2021) · The Lancet Diabetes & Endocrinology

Diabetes and associated disordersPancreatic function and diabetes

Cited by 186

Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: the environmental determinants of diabetes in the young (TEDDY)

Steck, A. K., Vehik, K., Bonifacio, E., Lernmark, A., Ziegler, A.-G., Hagopian, W. A., She, J., Simell, O., Akolkar, B., Krischer, J., et al. (2015) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 185

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: a prospective study in children

Bonifacio, E., Beyerlein, A., Hippich, M., Winkler, C., Vehik, K., Weedon, M. N., Laimighofer, M., Hattersley, A. T., Krumsiek, J., Frohnert, B. I., et al. (2018) · PLOS Medicine

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 148

A combined risk score enhances prediction of type 1 diabetes among susceptible children

Ferrat, L. A., Vehik, K., Sharp, S. A., Lernmark, Å., Rewers, M. J., She, J.-X., Ziegler, A.-G., Toppari, J., Akolkar, B., Krischer, J. P., et al. (2020) · Nature Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 148

TEDDY–The Environmental Determinants of Diabetes in the Young: An Observational Clinical Trial

HAGOPIAN, W. A., LERNMARK, Å., REWERS, M. J., SIMELL, O. G., SHE, J., ZIEGLER, A. G., KRISCHER, J. P., & AKOLKAR, B. (2006) · Annals of the New York Academy of Sciences

Diabetes and associated disordersDiabetes Management and Research

Cited by 125

Latent autoimmune diabetes of adults (LADA) is likely to represent a mixed population of autoimmune (type 1) and nonautoimmune (type 2) diabetes

Jones, A. G., McDonald, T. J., Shields, B. M., Hagopian, W., & Hattersley, A. T. (2021) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 122

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease: Intense follow-up enables early detection of type 1 diabetes

Elding Larsson, H., Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., Rewers, M., Simell, O., She, J.-X., et al. (2014) · Pediatric Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 103

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study

Vehik, K., Lynch, K. F., Schatz, D. A., Akolkar, B., Hagopian, W., Rewers, M., She, J.-X., Simell, O., Toppari, J., Ziegler, A.-G., et al. (2016) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 103

Islet Autoantibody Standardization Program 2018 workshop: interlaboratory comparison of glutamic acid decarboxylase autoantibody assay performance

Lampasona, V., Pittman, D. L., Williams, A. J., Achenbach, P., Schlosser, M., Akolkar, B., Winter, W. E., Laboratories, P., Watson, K., Weets, I., et al. (2019) · Clinical Chemistry

Diabetes and associated disordersClinical Laboratory Practices and Quality Control

Cited by 103

Islet autoimmunity and HLA markers of presymptomatic and clinical type 1 diabetes: joint analyses of prospective cohort studies in Finland, Germany, Sweden, and the U.S

Anand, V., Li, Y., Liu, B., Ghalwash, M., Koski, E., Ng, K., Dunne, J. L., Jönsson, J., Winkler, C., Knip, M., et al. (2021) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 83

Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes

Phillip, M., Achenbach, P., Addala, A., Albanese-O’Neill, A., Battelino, T., Bell, K. J., Besser, R. E. J., Bonifacio, E., Colhoun, H. M., Couper, J. J., et al. (2024) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 79

Islet cell and glutamic acid decarboxylase antibodies present at diagnosis of diabetes predict the need for insulin treatment. A cohort study in young adults whose disease was initially labeled as type 2 or unclassifiable diabetes.

Littorin, B., Sundkvist, G., Hagopian, W., Landin-Olsson, M., Lernmark, A., Ostman, J., Arnqvist, H. J., Blohmé, G., Bolinder, J., Eriksson, J. W., et al. (1999) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 72

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls: STECK et al .

Steck, A. K., Larsson, H. E., Liu, X., Veijola, R., Toppari, J., Hagopian, W. A., Haller, M. J., Ahmed, S., Akolkar, B., Lernmark, Å., et al. (2017) · Pediatric Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 56

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

Jacobsen, L. M., Larsson, H. E., Tamura, R. N., Vehik, K., Clasen, J., Sosenko, J., Hagopian, W. A., She, J., Steck, A. K., Rewers, M., et al. (2019) · Pediatric Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 48