A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM

Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine

ZWEIG, M. H., & Campbell, G. (1993) · Clinical Chemistry · doi:10.1093/clinchem/39.4.561 · Cited by 6,528 · see citing works

Basic principles of ROC analysis

Metz, C. E. (1978) · Seminars in Nuclear Medicine · doi:10.1016/s0001-2998(78)80014-2 · Cited by 6,058 · see citing works

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

Baekkeskov, S., Aanstoot, H.-J., Christgai, S., Reetz, A., Solimena, M., Cascalho, M., Folli, F., Richter-Olesen, H., & Camilli, P.-D. (1990) · Nature · doi:10.1038/347151a0 · Cited by 1,964 · see citing works

A Prospective Study of Indexes Predicting the Outcome of Trials of Weaning from Mechanical Ventilation

Yang, K. L., & Tobin, M. J. (1991) · New England Journal of Medicine · doi:10.1056/nejm199105233242101 · Cited by 1,384 · see citing works

Two genes encode distinct glutamate decarboxylases

Erlander, M. G., Tillakaratne, N. J. K., Feldblum, S., Patel, N., & Tobin, A. J. (1991) · Neuron · doi:10.1016/0896-6273(91)90077-d · Cited by 1,213 · see citing works

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

Bækkeskov, S., Nielsen, J. H., Marner, B., Bilde, T., Ludvigsson, J., & Lernmark, Å. (1982) · Nature · doi:10.1038/298167a0 · Cited by 530 · see citing works

Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.

Bu, D.-F., Erlander, M. G., Hitz, B. C., Tillakaratne, N. J. K., Kaufman, D. L., Wagner-McPherson, C., Evans, G. A., & Tobin, A. J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.6.2115 · Cited by 493 · see citing works

Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus

Kaufman, D. L., Erlander, M. G., Clare-Salzler, M., Atkinson, M. A., Maclaren, N. K., & Tobin, A. J. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115573 · Cited by 490 · see citing works

Erratum: Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

Bækkeskov, S., Aanstoot, H., Christgau, S., Reetz, A., Solimena, M., Cascalho, M., Folli, F. B., Richter-Olesen, H., & Camilli, P. V. D. (1990) · Nature · doi:10.1038/347782a0 · Cited by 352 · see citing works

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes.

Bækkeskov, S., Landin, M., Kristensen, J. K., Srikanta, S., Bruining, G. J., Mandrup-Poulsen, T. R., de Beaufort, C. E., Soeldner, J. S., Eisenbarth, G. S., & Lindgren, F. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112903 · Cited by 315 · see citing works

Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10.

Karlsen, A. E., Hagopian, W., Grubin, C. E., Dube, S., Distèche, C. M., Adler, D. A., Bärmeier, H., Mathewes, S. L., Grant, F. J., & Foster, D. C. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.19.8337 · Cited by 279 · see citing works

64 000 Mr autoantibodies as predictors of insulin-dependent diabetes

Atkinson, M. A., Maclaren, N. K., Riley, W. J., Sharp, D., & Lacey, P. E. (1990) · The Lancet · doi:10.1016/0140-6736(90)91241-2 · Cited by 203 · see citing works

Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type.

Hagopian, W., Karlsen, A. E., Gottsäter, A., Landin‐Olsson, M., Grubin, C. E., Sundkvist, G., Petersen, J. S., Boel, E., Dyrberg, T., & Lernmark, Å. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116195 · Cited by 199 · see citing works

The Swedish childhood diabetes study ? results from a nine year case register and a one year case-referent study indicating that Type 1 (insulin-dependent) diabetes mellitus is associated with both Type 2 (non-insulin-dependent) diabetes mellitus and autoimmune disorders

Dahlquist, G. G., Blom, L., Tuvemo, T., Nystr�m, L., Sandstr�m, A., & Wall, S. (1989) · Diabetologia · doi:10.1007/bf00265396 · Cited by 187 · see citing works

Antibodies to Glutamic Acid Decarboxylase Discriminate Major Types of Diabetes Mellitus

Rowley, M. J., Mackay, I. R., Chen, Q.-Y., et al. (1992) · Diabetes · doi:10.2337/diab.41.4.548 · Cited by 154 · see citing works

Immunology and Diabetes Workshops: report of the first international workshop on the standardisation of cytoplasmic islet cell antibodies

Bottazzo, G. F., & Gleichmann, H. (1986) · Diabetologia · doi:10.1007/bf00456124 · Cited by 145 · see citing works

Plasmapheresis in the initial treatment of insulin-dependent diabetes mellitus in children.

Ludvigsson, J., Hedïng, L. G., Liedén, G., Marner, B., & Lernmark, Å. (1983) · BMJ · doi:10.1136/bmj.286.6360.176 · Cited by 144 · see citing works

Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase

Hagopian, W., Michelsen, B. K., Karlsen, A. E., et al. (1993) · Diabetes · doi:10.2337/diabetes.42.4.631 · Cited by 134 · see citing works

Monoclonal antibodies to glutamic acid decarboxylase.

Gottlieb, D. I., Chang, Y.-M., & Schwob, J. E. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.22.8808 · Cited by 129 · see citing works

Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes.

Atkinson, M. A., Kaufman, D. L., Newman, D., Tobin, A. J., & Maclaren, N. K. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116192 · Cited by 121 · see citing works

Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble.

Christgau, S., Schierbeck, H., Aanstoot, H., et al. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54849-3 · Cited by 117 · see citing works

Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression.

Velloso, L. A., Kämpe, O., Hallberg, A., Christmanson, L., Betsholtz, C., & Karlsson, F. A. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116431 · Cited by 116 · see citing works

Predictive value of islet cell and insulin autoantibodies for Type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children

Landin‐Olsson, M., Palmer, J. P., Lernmark, Å., Blom, L., Sundkvist, G., Nyström, L., & Dahlquist, G. G. (1992) · Diabetologia · doi:10.1007/bf02221683 · Cited by 112 · see citing works

Estimating Mortality Risk in Preperative Patients Using Immunologic, Nutritional, and Acute-Phase Response Variables

Christou, N. V., Tellado-Rodriguez, J., Chartrand, L., GIANNAS, B., Meakins, J., Rode, H., & Gordon, J. (1989) · Annals of Surgery · doi:10.1097/00000658-198907000-00011 · Cited by 112 · see citing works

Serum exchange and use of dilutions have improved precision of measurement of islet cell antibodies

Bonifacio, E. E., Lernmark, Å., & Dawkins, R. L. (1988) · Journal of Immunological Methods · doi:10.1016/0022-1759(88)90274-8 · Cited by 110 · see citing works

Autoantibodies in IDDM Primarily Recognize the 65,000-Mr Rather Than 67,000-Mr Isoform of Glutamic Acid Decarboxylase

Hagopian, W., Michelsen, B. K., Karlsen, A. E., et al. (1993) · Diabetes · doi:10.2337/diab.42.4.631 · Cited by 101 · see citing works

Recombinant Glutamic Acid Decarboxylase (Representing the Single Isoform Expressed in Human Islets) Detects IDDM-Associated 64,000-Mr Autoantibodies

Karlsen, A. E., Hagopian, W., Petersen, J. S., Boel, E., Dyrberg, T., Grubin, C. E., Michelsen, B. K., Madsen, O. D., & Lernmark, Å. (1992) · Diabetes · doi:10.2337/diab.41.10.1355 · Cited by 99 · see citing works

Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes

Christie, M. R., Landin‐Olsson, M., Sundkvist, G., et al. (1988) · Diabetologia · doi:10.1007/bf00264766 · Cited by 97 · see citing works

Differential Expression of Glutamic Acid Decarboxylase in Rat and Human Islets

Petersen, J. S., Russel, S., Marshall, M. O., Kofod, H., Buschard, K., Cambon, N., Karlsen, A. E., Boel, E., Hagopian, W., Hejnæs, K. R., et al. (1993) · Diabetes · doi:10.2337/diab.42.3.484 · Cited by 96 · see citing works

Prolonged incubation in the two-colour immunofluorescence test increases the prevalence and titres of islet cell antibodies in Type 1 (insulin-dependent) diabetes mellitus

Olsson, M. L., Sundkvist, G., & Lernmark, Å. (1987) · Diabetologia · doi:10.1007/bf00299026 · Cited by 95 · see citing works

Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus.

Michelsen, B. K., Petersen, J. S., Boel, E., Møldrup, A., Dyrberg, T., & Madsen, O. D. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.19.8754 · Cited by 94 · see citing works

Prevalence of autoantibodies to the 65- and 67-kD isoforms of glutamate decarboxylase in insulin-dependent diabetes mellitus.

Seißler, J., Amann, J., Mauch, L., et al. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116714 · Cited by 78 · see citing works

The Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies

Lernmark, Å., Molenaar, J. L., van Beers, W. A. M., Yamaguchi, Y., Nagataki, S., Ludvigsson, J., Maclaren, N. K., Arnaiz‐Villena, A., Barbosa, J., deBeaufort, C., et al. (1991) · Diabetologia · doi:10.1007/bf00403293 · Cited by 69 · see citing works

Islet cell antibodies ? Theoretical and practical implications

Lernmark, Å., & Bækkeskov, S. (1981) · Diabetologia · doi:10.1007/bf00257781 · Cited by 67 · see citing works

Islet cell and other organ-specific autoantibodies in all children developing Type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched control children

Landin-Olsson, M., Karlsson, A., Dahlquist, G., Blom, L., Lernmark, Å., & Sundkvist, G. (1989) · Diabetologia · doi:10.1007/bf00277264 · Cited by 48 · see citing works

Autoantibodies to glutamic acid decarboxylase (GAD) detected by an immuno-trapping enzyme activity assay: Relation to insulin-dependent diabetes mellitus and islet cell antibodies

Martino, G., Tappaz, M., Braghi, S., et al. (1991) · Journal of Autoimmunity · doi:10.1016/0896-8411(91)90054-g · Cited by 47 · see citing works

An ELISA for Antibodies to Recombinant Glutamic Acid Decarboxylase in IDDM

DeAizpurua, H. J., Harrison, L. C., & Cram, D. S. (1992) · Diabetes · doi:10.2337/diab.41.9.1182 · Cited by 40 · see citing works

Immunology and Diabetes Workshops: Report of the Second International Workshop on the Standardisation of Cytoplasmic Islet Cell Antibodies

Bonifacio, E. E., Dawkins, R. L., & Lernmark, Å. (1987) · Diabetologia · doi:10.1007/bf00270427 · Cited by 38 · see citing works

Islet cell antibodies in insulin-dependent (type 1) diabetic children treated with plasmapheresis.

Marner, B., Lernmark, Å., Ludvigsson, J., et al. (1985) · PubMed · Cited by 25 · see citing works

Glutamic acid decarboxylase in insulin‐dependent diabetes mellitus

DeAizpurua, H. J., & Harrison, L. C. (1992) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610080205 · Cited by 23 · see citing works

Risk for developing Type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies

Barmeier, H., Mcculloch, D., Neifing, J. L., Warnock, G., Rajotte, R., Palmer, J., & Lernmark, Å. (1991) · Diabetologia · doi:10.1007/bf00401518 · Cited by 15 · see citing works

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Kirkman, M. S., Lernmark, A., Metzger, B. E., & Nathan, D. M. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.161596 · Cited by 1,360 · see citing works

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Kirkman, M. S., Lernmark, A., Metzger, B. E., & Nathan, D. M. (2011) · Diabetes Care · doi:10.2337/dc11-9998 · Cited by 718 · see citing works

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Lernmark, Å., Metzger, B. E., Nathan, D. M., & Kirkman, M. S. (2023) · Diabetes Care · doi:10.2337/dci23-0036 · Cited by 351 · see citing works

SEARCH for Diabetes in Youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth

(2004) · Controlled Clinical Trials · doi:10.1016/j.cct.2004.08.002 · Cited by 268 · see citing works

Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1

Orban, T., Sosenko, J. M., Cuthbertson, D., Krischer, J. P., Skyler, J. S., Jackson, R., Yu, L., Palmer, J. P., Schatz, D., Eisenbarth, G., et al. (2009) · Diabetes Care · doi:10.2337/dc09-0934 · Cited by 260 · see citing works

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

Graham, J., Hagopian, W. A., Kockum, I., Li, L. S., Sanjeevi, C. B., Lowe, R. M., Schaefer, J. B., Zarghami, M., Day, H. L., Landin-Olsson, M., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.5.1346 · Cited by 230 · see citing works

Lack of Association Between Early Exposure to Cow's Milk Protein and β-Cell Autoimmunity: Diabetes Autoimmunity Study in the Young (DAISY)

Norris, J. M. (1996) · JAMA · doi:10.1001/jama.1996.03540080031025 · Cited by 177 · see citing works

The World Health Organization International Collaborative Study for islet cell antibodies

Mire-Sluis, A. R., Gaines Das, R., & Lernmark, &. (2000) · Diabetologia · doi:10.1007/s001250051524 · Cited by 122 · see citing works

Risk assessment, prediction and prevention of type 1 diabetes

Harrison, L. C. (2001) · Pediatric Diabetes · doi:10.1034/j.1399-5448.2001.002002071.x · Cited by 48 · see citing works

Immunomodulation with human recombinant autoantigens

Lernmark, Å., & Agardh, C.-D. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.08.015 · Cited by 24 · see citing works

Glutamic Acid Decarboxylase Autoantibodies in Stiff-Man Syndrome

Kaufman, D. L. (1996) · Elsevier eBooks · doi:10.1016/b978-044482383-0/50045-5 · Cited by 1 · see citing works

Autoantibodies, detection methods and panels for diagnosis of Sjögren's syndrome

Shen, L., & Suresh, L. (2017) · Clinical Immunology · doi:10.1016/j.clim.2017.03.017 · Cited by 66 · see citing works

[Expression of recombinant human ZP3 protein using the baculovirus expression system].

Lu, H., Diao, H., Xiao, Y.-F., et al. (2014) · PubMed

Rat‐1 Fibroblasts Engineered with GAD65 and GAD67 cDNAs in Retroviral Vectors Produce and Release GABA

Ruppert, C., Sandrasagra, A., Antón, B., et al. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb02186.x · Cited by 20 · see citing works

Occurence of autoantibodies in healthy Omani individuals

Al-Jabri, A. A., & Richens, E. R. (2001) · Sultan Qaboos University medical journal · doi:10.18295/2075-0528.2574 · Cited by 5 · see citing works