Potthoff, Matthew J.

MEF2: a central regulator of diverse developmental programs

Potthoff, M. J., & Olson, E. N. (2007) · Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 834

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Potthoff, M. J., Inagaki, T., Satapati, S., Ding, X., He, T., Goetz, R., Mohammadi, M., Finck, B. N., Mangelsdorf, D. J., Kliewer, S. A., et al. (2009) · Proceedings of the National Academy of Sciences

Fibroblast Growth Factor ResearchPeroxisome Proliferator-Activated Receptors

Cited by 704

Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

Markan, K. R., Naber, M. C., Ameka, M. K., Anderegg, M. D., Mangelsdorf, D. J., Kliewer, S. A., Mohammadi, M., & Potthoff, M. J. (2014) · Diabetes

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 590

Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

Potthoff, M. J., Kliewer, S. A., & Mangelsdorf, D. J. (2012) · Genes & Development

Fibroblast Growth Factor ResearchGDF15 and Related Biomarkers

Cited by 442

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

Potthoff, M. J., Boney-Montoya, J., Choi, M., He, T., Sunny, N. E., Satapati, S., Suino-Powell, K., Xu, H. E., Gerard, R. D., Finck, B. N., et al. (2011) · Cell Metabolism

Fibroblast Growth Factor ResearchMetabolism, Diabetes, and Cancer

Cited by 431

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Zhang, Y., Xie, Y., Berglund, E. D., Coate, K. C., He, T. T., Katafuchi, T., Xiao, G., Potthoff, M. J., Wei, W., Wan, Y., et al. (2012) · eLife

Fibroblast Growth Factor ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 420

FGF21 mediates endocrine control of simple sugar intake and sweet taste preference by the liver

von Holstein-Rathlou, S., BonDurant, L. D., Peltekian, L., Naber, M. C., Yin, T. C., Claflin, K. E., Urizar, A. I., Madsen, A. N., Ratner, C., Holst, B., et al. (2016) · Cell Metabolism

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 347

FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms

BonDurant, L. D., Ameka, M., Naber, M. C., Markan, K. R., Idiga, S. O., Acevedo, M. R., Walsh, S. A., Ornitz, D. M., & Potthoff, M. J. (2017) · Cell Metabolism

Fibroblast Growth Factor ResearchAdipose Tissue and Metabolism

Cited by 330

Metabolic messengers: FGF21

Flippo, K. H., & Potthoff, M. J. (2021) · Nature Metabolism

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 311

Hepatokines and metabolism: Deciphering communication from the liver

Jensen-Cody, S. O., & Potthoff, M. J. (2021) · Molecular Metabolism

Adipokines, Inflammation, and Metabolic DiseasesLiver Disease Diagnosis and Treatment

Cited by 252

Obesity-associated NLRC4 inflammasome activation drives breast cancer progression

Kolb, R., Phan, L., Borcherding, N., Liu, Y., Yuan, F., Janowski, A. M., Xie, Q., Markan, K. R., Li, W., Potthoff, M. J., et al. (2016) · Nature Communications

Inflammasome and immune disordersImmune cells in cancer

Cited by 239

Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis

BonDurant, L. D., & Potthoff, M. J. (2018) · Annual Review of Nutrition

Fibroblast Growth Factor ResearchFolate and B Vitamins Research

Cited by 222

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

Søberg, S., Sandholt, C. H., Jespersen, N. Z., Toft, U., Madsen, A. L., von Holstein-Rathlou, S., Grevengoed, T. J., Christensen, K. B., Bredie, W. L. P., Potthoff, M. J., et al. (2017) · Cell Metabolism

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 216

OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance

Pereira, R. O., Tadinada, S. M., Zasadny, F. M., Oliveira, K. J., Pires, K. M. P., Olvera, A., Jeffers, J., Souvenir, R., Mcglauflin, R., Seei, A., et al. (2017) · The EMBO Journal

Fibroblast Growth Factor ResearchMitochondrial Function and Pathology

Cited by 211

FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake

Jensen-Cody, S. O., Flippo, K. H., Claflin, K. E., Yavuz, Y., Sapouckey, S. A., Walters, G. C., Usachev, Y. M., Atasoy, D., Gillum, M. P., & Potthoff, M. J. (2020) · Cell Metabolism

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 166

Metabolic fibroblast growth factors (FGFs): Mediators of energy homeostasis

Markan, K. R., & Potthoff, M. J. (2016) · Seminars in Cell & Developmental Biology

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 103

Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure

Ameka, M., Markan, K. R., Morgan, D. A., BonDurant, L. D., Idiga, S. O., Naber, M. C., Zhu, Z., Zingman, L. V., Grobe, J. L., Rahmouni, K., et al. (2019) · Scientific Reports

Fibroblast Growth Factor ResearchAdipose Tissue and Metabolism

Cited by 93

Angiopoietin-like 4 directs uptake of dietary fat away from adipose during fasting

Cushing, E. M., Chi, X., Sylvers, K. L., Shetty, S. K., Potthoff, M. J., & Davies, B. S. J. (2017) · Molecular Metabolism

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 88

FGF21 reverses MASH through coordinated actions on the CNS and liver

Rose, J. P., Morgan, D. A., Sullivan, A. I., Fu, X., Inigo-Vollmer, M., Burgess, S. C., Meyerholz, D. K., Rahmouni, K., & Potthoff, M. J. (2025) · Cell Metabolism

Fibroblast Growth Factor ResearchLiver Disease Diagnosis and Treatment

Cited by 75

A new frontier in FGF21 biology

Potthoff, M. J. (2017) · Nature Reviews Endocrinology

Fibroblast Growth Factor ResearchParathyroid Disorders and Treatments

Cited by 63

FGF21 signaling in glutamatergic neurons is required for weight loss associated with dietary protein dilution

Flippo, K. H., Jensen-Cody, S. O., Claflin, K. E., & Potthoff, M. J. (2020) · Scientific Reports

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 49