Smit, August B.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Multicenter Genetic Studies of Schizophrenia Consortium, Ripke, S., Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium 2, O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., et al. (2013) · Nature Genetics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 1,496

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., et al. (2019) · Neuron

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 938

Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways

Jansen, P. R., Watanabe, K., Stringer, S., Skene, N., Bryois, J., Hammerschlag, A. R., de Leeuw, C. A., Benjamins, J., Muñoz-Manchado, A. B., Nagel, M., et al. (2018) · Nature Genetics

Sleep and related disordersGenetic Associations and Epidemiology

Cited by 860

Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells

Gupta, I., Collier, P. G., Haase, B., Mahfouz, A., Joglekar, A., Floyd, T., Koopmans, F., Barres, B., Smit, A. B., Sloan, S. A., et al. (2018) · Nature Biotechnology

Single-cell and spatial transcriptomicsRNA Research and Splicing

Cited by 343

Oligodendroglial myelination requires astrocyte-derived lipids

Camargo, N., Goudriaan, A., van Deijk, A.-L. F., Otte, W. M., Brouwers, J. F., Lodder, H., Gutmann, D. H., Nave, K.-A., Dijkhuizen, R. M., Mansvelder, H. D., et al. (2017) · PLOS Biology

Neurogenesis and neuroplasticity mechanismsLipid metabolism and biosynthesis

Cited by 296

CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

De Rubeis, S., Pasciuto, E., Li, K. W., Fernández, E., Di Marino, D., Buzzi, A., Ostroff, L. E., Klann, E., Zwartkruis, F. J. T., Komiyama, N. H., et al. (2013) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 296

Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats

Adriani, W., Spijker, S., Deroche-Gamonet, V., Laviola, G., Le Moal, M., Smit, A. B., & Piazza, P. V. (2003) · The Journal of Neuroscience

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 257

Distributed Network Actions by Nicotine Increase the Threshold for Spike-Timing-Dependent Plasticity in Prefrontal Cortex

Couey, J. J., Meredith, R. M., Spijker, S., Poorthuis, R. B., Smit, A. B., Brussaard, A. B., & Mansvelder, H. D. (2007) · Neuron

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 253

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Joglekar, A., Prjibelski, A., Mahfouz, A., Collier, P., Lin, S., Schlusche, A. K., Marrocco, J., Williams, S. R., Haase, B., Hayes, A., et al. (2021) · Nature Communications

RNA Research and SplicingSingle-cell and spatial transcriptomics

Cited by 229

Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer’s disease

Hijazi, S., Heistek, T. S., Scheltens, P., Neumann, U., Shimshek, D. R., Mansvelder, H. D., Smit, A. B., & van Kesteren, R. E. (2020) · Molecular Psychiatry

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 216

Optogenetic dissection of medial prefrontal cortex circuitry

Riga, D., Matos, M. R., Glas, A., Smit, A. B., Spijker, S., & Van den Oever, M. C. (2014) · Frontiers in Systems Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 208

Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking

Van den Oever, M. C., Goriounova, N. A., Wan Li, K., Van der Schors, R. C., Binnekade, R., Schoffelmeer, A. N. M., Mansvelder, H. D., Smit, A. B., Spijker, S., & De Vries, T. J. (2008) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 206

Astrocyte lipid metabolism is critical for synapse development and function in vivo

van Deijk, A. F., Camargo, N., Timmerman, J., Heistek, T., Brouwers, J. F., Mogavero, F., Mansvelder, H. D., Smit, A. B., & Verheijen, M. H. G. (2017) · Glia

Neuroscience and Neuropharmacology ResearchLipid metabolism and biosynthesis

Cited by 201

Retrieval-specific endocytosis of GluA2-AMPARs underlies adaptive reconsolidation of contextual fear

Rao-Ruiz, P., Rotaru, D. C., van der Loo, R. J., Mansvelder, H. D., Stiedl, O., Smit, A. B., & Spijker, S. (2011) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 192

Nicotinic acetylcholine receptor β2 subunits in the medial prefrontal cortex control attention

Guillem, K., Bloem, B., Poorthuis, R. B., Loos, M., Smit, A. B., Maskos, U., Spijker, S., & Mansvelder, H. D. (2011) · Science

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 191

Long-Lasting Cognitive Deficits Resulting from Adolescent Nicotine Exposure in Rats

Counotte, D. S., Spijker, S., Van de Burgwal, L. H., Hogenboom, F., Schoffelmeer, A. N. M., De Vries, T. J., Smit, A. B., & Pattij, T. (2009) · Neuropsychopharmacology

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 163

Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence

Counotte, D. S., Goriounova, N. A., Li, K. W., Loos, M., van der Schors, R. C., Schetters, D., Schoffelmeer, A. N. M., Smit, A. B., Mansvelder, H. D., Pattij, T., et al. (2011) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 132

Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats

Riga, D., Kramvis, I., Koskinen, M. K., van Bokhoven, P., van der Harst, J. E., Heistek, T. S., Jaap Timmerman, A., van Nierop, P., van der Schors, R. C., Pieneman, A. W., et al. (2017) · Science Translational Medicine

Treatment of Major DepressionMemory and Neural Mechanisms

Cited by 128

Evolution of the vasopressin/oxytocin superfamily: characterization of a cDNA encoding a vasopressin-related precursor, preproconopressin, from the mollusc Lymnaea stagnalis.

van Kesteren, R. E., Smit, A. B., Dirks, R. W., de With, N. D., Geraerts, W. P., & Joosse, J. (1992) · Proceedings of the National Academy of Sciences

Neuropeptides and Animal PhysiologyNeuroendocrine regulation and behavior

Cited by 120

SCAP is required for timely and proper myelin membrane synthesis

Verheijen, M. H. G., Camargo, N., Verdier, V., Nadra, K., de Preux Charles, A.-S., Médard, J.-J., Luoma, A., Crowther, M., Inouye, H., Shimano, H., et al. (2009) · Proceedings of the National Academy of Sciences

Lipid metabolism and biosynthesisCancer, Lipids, and Metabolism

Cited by 119

Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue

Hardwick, S. A., Hu, W., Joglekar, A., Fan, L., Collier, P. G., Foord, C., Balacco, J., Lanjewar, S., Sampson, M. M., Koopmans, F., et al. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsRNA Research and Splicing

Cited by 119

Specific Glial Functions Contribute to Schizophrenia Susceptibility

Goudriaan, A., de Leeuw, C., Ripke, S., Hultman, C. M., Sklar, P., Sullivan, P. F., Smit, A. B., Posthuma, D., & Verheijen, M. H. G. (2014) · Schizophrenia Bulletin

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 114

Measuring behavior in the home cage: study design, applications, challenges, and perspectives

Grieco, F., Bernstein, B. J., Biemans, B., Bikovski, L., Burnett, C. J., Cushman, J. D., van Dam, E. A., Fry, S. A., Richmond-Hacham, B., Homberg, J. R., et al. (2021) · Frontiers in Behavioral Neuroscience

Animal Behavior and Welfare StudiesNeuroscience and Neuropharmacology Research

Cited by 109