Thorburn, David R.

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

Pagliarini, D. J., Calvo, S. E., Chang, B., Sheth, S. A., Vafai, S. B., Ong, S.-E., Walford, G. A., Sugiana, C., Boneh, A., Chen, W. K., et al. (2008) · Cell

Mitochondrial Function and PathologyAdvanced Proteomics Techniques and Applications

Cited by 1,994

Understanding mitochondrial complex I assembly in health and disease

Mimaki, M., Wang, X., McKenzie, M., Thorburn, D. R., & Ryan, M. T. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyEnzyme Structure and Function

Cited by 420

Mitochondrial disorders: prevalence, myths and advances

Thorburn, D. R. (2004) · Journal of Inherited Metabolic Disease

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 258

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

Dai, N., Zhao, L., Wrighting, D., Krämer, D., Majithia, A., Wang, Y., Cracan, V., Borges-Rivera, D., Mootha, V. K., Nahrendorf, M., et al. (2015) · Cell Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 188

Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models

Komen, J. C., & Thorburn, D. R. (2014) · British Journal of Pharmacology

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 149

High-intensity training induces non-stoichiometric changes in the mitochondrial proteome of human skeletal muscle without reorganisation of respiratory chain content

Granata, C., Caruana, N. J., Botella, J., Jamnick, N. A., Huynh, K., Kuang, J., Janssen, H. A., Reljic, B., Mellett, N. A., Laskowski, A., et al. (2021) · Nature Communications

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 93

Quantifying constraint in the human mitochondrial genome

Lake, N. J., Liu, W., Battle, S. L., Laricchia, K. M., Tiao, G., Puiu, D., Compton, A. G., Cowie, S., Christodoulou, J., Thorburn, D. R., et al. (2022) · Nature

Genomics and Rare DiseasesMitochondrial Function and Pathology

Cited by 63

Quantifying constraint in the human mitochondrial genome

Lake, N. J., Ma, K., Liu, W., Battle, S. L., Laricchia, K. M., Tiao, G., Puiu, D., Ng, K. K., Cohen, J., Compton, A. G., et al. (2024) · Nature

Genomics and Rare DiseasesMitochondrial Function and Pathology

Cited by 63

Early diagnosis of Pearson syndrome in neonatal intensive care following rapid mitochondrial genome sequencing in tandem with exome sequencing.

Akesson, L. S., Eggers, S., Love, C. J., Chong, B., Krzesinski, E. I., Brown, N. J., Tan, T. Y., Richmond, C. M., Thorburn, D. R., Christodoulou, J., et al. (2019) · European Journal of Human Genetics

Genomics and Rare DiseasesMitochondrial Function and Pathology

Cited by 28