Rupprecht, Rainer

Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

Binder, E. B., Salyakina, D., Lichtner, P., Wochnik, G. M., Ising, M., Pütz, B., Papiol, S., Seaman, S., Lucae, S., Kohli, M. A., et al. (2004) · Nature Genetics

Stress Responses and CortisolGenetic Associations and Epidemiology

Cited by 977

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Rupprecht, R., Papadopoulos, V., Rammes, G., Baghai, T. C., Fan, J., Akula, N., Groyer, G., Adams, D., & Schumacher, M. (2010) · Nature Reviews Drug Discovery

Pharmacological Receptor Mechanisms and EffectsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 930

Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

Rupprecht, R. (2003) · Psychoneuroendocrinology

Neuroscience and Neuropharmacology ResearchEstrogen and related hormone effects

Cited by 427

Association of the Brain-Derived Neurotrophic Factor Val66Met Polymorphism With Reduced Hippocampal Volumes in Major Depression

Frodl, T., Schüle, C., Schmitt, G., Born, C., Baghai, T., Zill, P., Bottlender, R., Rupprecht, R., Bondy, B., Reiser, M., et al. (2007) · Archives of General Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 394

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

Rupprecht, R., Rammes, G., Eser, D., Baghai, T. C., Schüle, C., Nothdurfter, C., Troxler, T., Gentsch, C., Kalkman, H. O., Chaperon, F., et al. (2009) · Science

Pharmacological Receptor Mechanisms and EffectsNeuroscience and Neuropharmacology Research

Cited by 328

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

Zill, P., Baghai, T. C., Zwanzger, P., Schüle, C., Eser, D., Rupprecht, R., Möller, H.-J., Bondy, B., & Ackenheil, M. (2004) · Molecular Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 323

Minocycline alters behavior, microglia and the gut microbiome in a trait-anxiety-dependent manner

Schmidtner, A. K., Slattery, D. A., Gläsner, J., Hiergeist, A., Gryksa, K., Malik, V. A., Hellmann-Regen, J., Heuser, I., Baghai, T. C., Gessner, A., et al. (2019) · Translational Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 153

Acute prefrontal rTMS increases striatal dopamine to a similar degree as D-amphetamine

Pogarell, O., Koch, W., Pöpperl, G., Tatsch, K., Jakob, F., Mulert, C., Grossheinrich, N., Rupprecht, R., Möller, H.-J., Hegerl, U., et al. (2007) · Psychiatry Research Neuroimaging

Transcranial Magnetic Stimulation StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 133

Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial

Hellmann-Regen, J., Clemens, V., Grözinger, M., Kornhuber, J., Reif, A., Prvulovic, D., Goya-Maldonado, R., Wiltfang, J., Gruber, O., Schüle, C., et al. (2022) · JAMA Network Open

Treatment of Major DepressionTryptophan and brain disorders

Cited by 100

Neurosteroids: molecular mechanisms of action and psychopharmacological significance

Rupprecht, R., Hauser, C. A. E., Trapp, T., & Holsboer, F. (1996) · The Journal of Steroid Biochemistry and Molecular Biology

Neuroscience and Neuropharmacology ResearchEstrogen and related hormone effects

Cited by 99

Brain-derived neurotrophic factor Val66Met polymorphism and dexamethasone/CRH test results in depressed patients

Schüle, C., Zill, P., Baghai, T. C., Eser, D., Zwanzger, P., Wenig, N., Rupprecht, R., & Bondy, B. (2006) · Psychoneuroendocrinology

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 94

Fluoxetine Requires the Endfeet Protein Aquaporin-4 to Enhance Plasticity of Astrocyte Processes

Di Benedetto, B., Malik, V. A., Begum, S., Jablonowski, L., Gómez-González, G. B., Neumann, I. D., & Rupprecht, R. (2016) · Frontiers in Cellular Neuroscience

Treatment of Major DepressionIon Transport and Channel Regulation

Cited by 77

Axonal Regeneration and Neuroinflammation: Roles for the Translocator Protein 18 kDa

Girard, C., Liu, S., Adams, D., Lacroix, C., Sinéus, M., Boucher, C., Papadopoulos, V., Rupprecht, R., Schumacher, M., & Groyer, G. (2012) · Journal of Neuroendocrinology

Nerve injury and regenerationTraumatic Brain Injury and Neurovascular Disturbances

Cited by 75

Tryptophan Metabolism and Immunogenetics in Major Depression: A Role for Interferon-γ Gene

Myint, A. M., Bondy, B., Baghai, T. C., Eser, D., Nothdurfter, C., Schüle, C., Zill, P., Müller, N., Rupprecht, R., & Schwarz, M. J. (2013) · Brain, Behavior, and Immunity

Tryptophan and brain disordersTreatment of Major Depression

Cited by 74

In Vivo Assessment of Neuroinflammation in 4‐Repeat Tauopathies

Palleis, C., Sauerbeck, J., Beyer, L., Harris, S., Schmitt, J., Morenas‐Rodriguez, E., Finze, A., Nitschmann, A., Ruch‐Rubinstein, F., Eckenweber, F., et al. (2021) · Movement Disorders

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 62

Microglial Activation and Connectivity in Alzheimer Disease and Aging

Rauchmann, B., Brendel, M., Franzmeier, N., Trappmann, L., Zaganjori, M., Ersoezlue, E., Morenas‐Rodriguez, E., Guersel, S., Burow, L., Kurz, C., et al. (2022) · Annals of Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 61

Impact of Lipid Raft Integrity on 5-HT3 Receptor Function and its Modulation by Antidepressants

Nothdurfter, C., Tanasic, S., Di Benedetto, B., Rammes, G., Wagner, E.-M., Kirmeier, T., Ganal, V., Kessler, J. S., Rein, T., Holsboer, F., et al. (2010) · Neuropsychopharmacology

Neuroscience and Neuropharmacology ResearchLipid Membrane Structure and Behavior

Cited by 43

Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies

Finze, A., Biechele, G., Rauchmann, B.-S., Franzmeier, N., Palleis, C., Katzdobler, S., Weidinger, E., Guersel, S., Schuster, S., Harris, S., et al. (2023) · Molecular Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 40

Dose escalation of antidepressants in unipolar depression: a meta-analysis of double-blind, randomized controlled trials

Dold, M., Bartova, L., Rupprecht, R., & Kasper, S. (2017) · Psychotherapy and Psychosomatics

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 38

The Cytokine IL-17A as a Marker of Treatment Resistance in Major Depressive Disorder?

Nothdurfter, C., Milenkovic, V. M., Sarubin, N., Hilbert, S., Manook, A., Weigl, J., Almeqbaali, K., Wetzel, C. H., Rupprecht, R., & Baghai, T. C. (2021) · European Journal of Neuroscience

Tryptophan and brain disordersTreatment of Major Depression

Cited by 38

Severe chronic insomnia is not associated with higher body mass index

Crönlein, T., Langguth, B., Busch, V., Rupprecht, R., & Wetter, T. C. (2015) · Journal of Sleep Research

Sleep and related disordersSleep and Work-Related Fatigue

Cited by 34

Benzodiazepines counteract rostral anterior cingulate cortex activation induced by cholecystokinin-tetrapeptide in humans

Leicht, G., Mulert, C., Eser, D., Sämann, P. G., Ertl, M., Laenger, A., Karch, S., Pogarell, O., Meindl, T., Czisch, M., et al. (2013) · Biological Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeurotransmitter Receptor Influence on Behavior

Cited by 21

Computer-assisted avatar-based treatment for dysfunctional beliefs in depressive inpatients: A pilot study

Kocur, M., Dechant, M., Wolff, C., Nothdurfter, C., Wetter, T. C., Rupprecht, R., & Shiban, Y. (2021) · Frontiers in Psychiatry

Digital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 15