Colgan, Sean P.

Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function

Kelly, C. J., Zheng, L., Campbell, E. L., Saeedi, B., Scholz, C. C., Bayless, A. J., Wilson, K. E., Glover, L. E., Kominsky, D. J., Magnuson, A., et al. (2015) · Cell Host & Microbe

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 1,716

Resolvins

Serhan, C. N., Hong, S., Gronert, K., Colgan, S. P., Devchand, P. R., Mirick, G., & Moussignac, R.-L. (2002) · The Journal of Experimental Medicine

Fatty Acid Research and HealthInflammatory mediators and NSAID effects

Cited by 1,650

Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

Serhan, C. N., Clish, C. B., Brannon, J., Colgan, S. P., Chiang, N., & Gronert, K. (2000) · The Journal of Experimental Medicine

Fatty Acid Research and HealthInflammatory mediators and NSAID effects

Cited by 1,189

Regulation of Immunity and Inflammation by Hypoxia in Immunological Niches

Taylor, C. T., & Colgan, S. P. (2017) · Nature reviews. Immunology

Cancer, Hypoxia, and MetabolismImmune cells in cancer

Cited by 713

Ecto-5′-Nucleotidase (CD73) Regulation by Hypoxia-Inducible Factor-1 Mediates Permeability Changes in Intestinal Epithelia

Synnestvedt, K., Furuta, G. T., Comerford, K. M., Louis, N., Karhausen, J., Eltzschig, H. K., Hansen, K. R., Thompson, L. F., & Colgan, S. P. (2002) · Journal of Clinical Investigation

Adenosine and Purinergic SignalingBiochemical and Molecular Research

Cited by 660

Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis

Karhausen, J., Furuta, G. T., Tomaszewski, J. E., Johnson, R. S., Colgan, S. P., & Haase, V. H. (2004) · Journal of Clinical Investigation

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 655

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

Clambey, E. T., McNamee, E. N., Westrich, J. A., Glover, L. E., Campbell, E. L., Jedlicka, P., de Zoeten, E. F., Cambier, J. C., Stenmark, K. R., Colgan, S. P., et al. (2012) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 560

Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor

Alexeev, E. E., Lanis, J. M., Kao, D. J., Campbell, E. L., Kelly, C. J., Battista, K. D., Gerich, M. E., Jenkins, B. R., Walk, S. T., Kominsky, D. J., et al. (2018) · The American Journal of Pathology

Gut microbiota and healthInflammatory Bowel Disease

Cited by 532

Coordinated Adenine Nucleotide Phosphohydrolysis and Nucleoside Signaling in Posthypoxic Endothelium

Eltzschig, H. K., Ibla, J. C., Furuta, G. T., Leonard, M. O., Jacobson, K. A., Enjyoji, K., Robson, S. C., & Colgan, S. P. (2003) · The Journal of Experimental Medicine

Adenosine and Purinergic SignalingBiochemical and Molecular Research

Cited by 499

Hypoxia: an alarm signal during intestinal inflammation

Colgan, S. P., & Taylor, C. T. (2010) · Nature Reviews Gastroenterology & Hepatology

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 461

Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia

Furuta, G. T., Turner, J. R., Taylor, C. T., Hershberg, R. M., Comerford, K., Narravula, S., Podolsky, D. K., & Colgan, S. P. (2001) · The Journal of Experimental Medicine

Barrier Structure and Function StudiesDigestive system and related health

Cited by 449

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

Robinson, A., Keely, S., Karhausen, J., Gerich, M. E., Furuta, G. T., & Colgan, S. P. (2008) · Gastroenterology

Inflammatory Bowel DiseaseCancer, Hypoxia, and Metabolism

Cited by 368

Transepithelial Migration of Neutrophils

Zemans, R. L., Colgan, S. P., & Downey, G. P. (2009) · American Journal of Respiratory Cell and Molecular Biology

Neutrophil, Myeloperoxidase and Oxidative MechanismsCell Adhesion Molecules Research

Cited by 339

Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin

Wang, R. X., Lee, J. S., Campbell, E. L., & Colgan, S. P. (2020) · Proceedings of the National Academy of Sciences

Gut microbiota and healthInflammatory Bowel Disease

Cited by 318

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

Eckle, T., Hartmann, K., Bonney, S., Reithel, S., Mittelbronn, M., Walker, L. A., Lowes, B. D., Han, J., Borchers, C. H., Buttrick, P. M., et al. (2012) · Nature Medicine

Cardiac Ischemia and ReperfusionAdenosine and Purinergic Signaling

Cited by 314

Hypoxia and gastrointestinal disease

Taylor, C. T., & Colgan, S. P. (2007) · Journal of Molecular Medicine

Inflammatory Bowel DiseaseCancer, Hypoxia, and Metabolism

Cited by 313

Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia

Canny, G., Levy, O., Furuta, G. T., Narravula-Alipati, S., Sisson, R. B., Serhan, C. N., & Colgan, S. P. (2002) · Proceedings of the National Academy of Sciences

Antimicrobial Peptides and ActivitiesImmune Response and Inflammation

Cited by 295

Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of β 2 integrin gene expression

Kong, T., Eltzschig, H. K., Karhausen, J., Colgan, S. P., & Shelley, C. S. (2004) · Proceedings of the National Academy of Sciences

Cell Adhesion Molecules ResearchCancer, Hypoxia, and Metabolism

Cited by 242

Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution

Campbell, E. L., Louis, N. A., Tomassetti, S. E., Canny, G. O., Arita, M., Serhan, C. N., & Colgan, S. P. (2007) · The FASEB Journal

Fatty Acid Research and HealthInflammatory mediators and NSAID effects

Cited by 205

Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia

Comerford, K. M., Leonard, M. O., Karhausen, J., Carey, R., Colgan, S. P., & Taylor, C. T. (2003) · Proceedings of the National Academy of Sciences

Ubiquitin and proteasome pathwaysNF-κB Signaling Pathways

Cited by 185

Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis

Glover, L. E., Bowers, B. E., Saeedi, B., Ehrentraut, S. F., Campbell, E. L., Bayless, A. J., Dobrinskikh, E., Kendrick, A. A., Kelly, C. J., Burgess, A., et al. (2013) · Proceedings of the National Academy of Sciences

Inflammatory Bowel DiseaseCancer, Hypoxia, and Metabolism

Cited by 155

Selective induction of mucin‐3 by hypoxia in intestinal epithelia

Louis, N. A., Hamilton, K. E., Canny, G., Shekels, L. L., Ho, S. B., & Colgan, S. P. (2006) · Journal of Cellular Biochemistry

Digestive system and related healthGlycosylation and Glycoproteins Research

Cited by 144

Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores

Hartmann, H., Eltzschig, H. K., Wurz, H., Hantke, K., Rakin, A., Yazdi, A. S., Matteoli, G., Bohn, E., Autenrieth, I. B., Karhausen, J., et al. (2008) · Gastroenterology

Cancer, Hypoxia, and MetabolismImmune Response and Inflammation

Cited by 143

Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models

Feng, D., Xiang, X., Guan, Y., Guillot, A., Lu, H., Chang, C., He, Y., Wang, H., Pan, H., Ju, C., et al. (2023) · Journal of Clinical Investigation

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 93