Naganawa, Mika

Lower synaptic density is associated with depression severity and network alterations

Holmes, S. E., Scheinost, D., Finnema, S. J., Naganawa, M., Davis, M. T., DellaGioia, N., Nabulsi, N., Matuskey, D., Angarita, G. A., Pietrzak, R. H., et al. (2019) · Nature Communications

Treatment of Major DepressionFunctional Brain Connectivity Studies

Cited by 484

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

Chen, M.-K., Mecca, A. P., Naganawa, M., Finnema, S. J., Toyonaga, T., Lin, S.-F., Najafzadeh, S., Ropchan, J., Lu, Y., McDonald, J. W., et al. (2018) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 431

In vivo measurement of widespread synaptic loss in Alzheimer’s disease with SV2A PET

Mecca, A. P., Chen, M., O'Dell, R. S., Naganawa, M., Toyonaga, T., Godek, T. A., Harris, J. E., Bartlett, H. H., Zhao, W., Nabulsi, N. B., et al. (2020) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 288

Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [ 11 C]UCB‐J

Mecca, A. P., O'Dell, R. S., Sharp, E. S., Banks, E. R., Bartlett, H. H., Zhao, W., Lipior, S., Diepenbrock, N. G., Chen, M., Naganawa, M., et al. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 186

First-in-Human Evaluation of 18 F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A

Naganawa, M., Li, S., Nabulsi, N., Henry, S., Zheng, M.-Q., Pracitto, R., Cai, Z., Gao, H., Kapinos, M., Labaree, D., et al. (2021) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 138

Assessment of a white matter reference region for 11 C-UCB-J PET quantification

Rossano, S., Toyonaga, T., Finnema, S. J., Naganawa, M., Lu, Y., Nabulsi, N., Ropchan, J., De Bruyn, S., Otoul, C., Stockis, A., et al. (2020) · Journal of Cerebral Blood Flow & Metabolism

Medical Imaging Techniques and ApplicationsAdvanced MRI Techniques and Applications

Cited by 126

Imaging of Synaptic Density in Neurodegenerative Disorders

Carson, R. E., Naganawa, M., Toyonaga, T., Koohsari, S., Yang, Y., Chen, M.-K., Matuskey, D., & Finnema, S. J. (2022) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsAlzheimer's disease research and treatments

Cited by 104

In vivo evidence of lower synaptic vesicle density in schizophrenia

Radhakrishnan, R., Skosnik, P. D., Ranganathan, M., Naganawa, M., Toyonaga, T., Finnema, S., Hillmer, A. T., Esterlis, I., Huang, Y., Nabulsi, N., et al. (2021) · Molecular Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 100

First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer

Naganawa, M., Nabulsi, N., Henry, S., Matuskey, D., Lin, S.-F., Slieker, L., Schwarz, A. J., Kant, N., Jesudason, C., Ruley, K., et al. (2021) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 94

In Vivo Synaptic Density Imaging with 11 C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease

Toyonaga, T., Smith, L. M., Finnema, S. J., Gallezot, J.-D., Naganawa, M., Bini, J., Mulnix, T., Cai, Z., Ropchan, J., Huang, Y., et al. (2019) · Journal of Nuclear Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 79

Reduced synaptic vesicle protein 2A binding in temporal lobe epilepsy: A [11C]UCB‐J positron emission tomography study

Finnema, S. J., Toyonaga, T., Detyniecki, K., Chen, M., Dias, M., Wang, Q., Lin, S., Naganawa, M., Gallezot, J., Lu, Y., et al. (2020) · Epilepsia

Epilepsy research and treatmentMedical Imaging Techniques and Applications

Cited by 78

Imaging the effect of ketamine on synaptic density (SV2A) in the living brain

Holmes, S. E., Finnema, S. J., Naganawa, M., DellaGioia, N., Holden, D., Fowles, K., Davis, M., Ropchan, J., Emory, P., Ye, Y., et al. (2022) · Molecular Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 78

A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers

Finnema, S. J., Rossano, S., Naganawa, M., Henry, S., Gao, H., Pracitto, R., Maguire, R. P., Mercier, J., Kervyn, S., Nicolas, J., et al. (2019) · Epilepsia

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 65

Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A

Li, S., Naganawa, M., Pracitto, R., Najafzadeh, S., Holden, D., Henry, S., Matuskey, D., Emery, P. R., Cai, Z., Ropchan, J., et al. (2021) · European Journal of Nuclear Medicine and Molecular Imaging

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 61

Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder

D’Souza, D. C., Radhakrishnan, R., Naganawa, M., Ganesh, S., Nabulsi, N., Najafzadeh, S., Ropchan, J., Ranganathan, M., Cortes-Briones, J., Huang, Y., et al. (2021) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 55

Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11 C‐UCB‐J positron emission tomography study in humans

Angarita, G. A., Worhunsky, P. D., Naganawa, M., Toyonaga, T., Nabulsi, N. B., Li, C. R., Esterlis, I., Skosnik, P. D., Radhakrishnan, R., Pittman, B., et al. (2022) · Addiction Biology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 38

First-in-Human Study of18F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding

Drake, L. R., Wu, Y., Naganawa, M., Asch, R., Zheng, C., Najafzadeh, S., Pracitto, R., Lindemann, M., Li, S., Ropchan, J., et al. (2024) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 18

In vivo measurement of widespread synaptic loss and associated tau accumulation in early Alzheimer’s disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD

Mecca, A. P., O'Dell, R. S., Chen, M., Naganawa, M., Toyonaga, T., Godek, T. A., Harris, J. E., Bartlett, H. H., Zhao, W., Gallezot, J., et al. (2020) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 1