Ertürk, Ali

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

Parhizkar, S., Arzberger, T., Brendel, M., Kleinberger, G., Deussing, M., Focke, C., Nuscher, B., Xiong, M., Ghasemigharagoz, A., Katzmarski, N., et al. (2019) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections

Cai, R., Pan, C., Ghasemigharagoz, A., Todorov, M. I., Förstera, B., Zhao, S., Bhatia, H. S., Parra-Damas, A., Mrowka, L., Theodorou, D., et al. (2019) · Nature Neuroscience

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

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Machine learning analysis of whole mouse brain vasculature

Todorov, M. I., Paetzold, J. C., Schoppe, O., Tetteh, G., Shit, S., Efremov, V., Todorov-Völgyi, K., Düring, M., Dichgans, M., Piraud, M., et al. (2020) · Nature Methods

Medical Image Segmentation TechniquesCell Image Analysis Techniques

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Cellular and Molecular Probing of Intact Human Organs

Zhao, S., Todorov, M. I., Cai, R., -Maskari, R. A., Steinke, H., Kemter, E., Mai, H., Rong, Z., Warmer, M., Stanic, K., et al. (2020) · Cell

Advanced Fluorescence Microscopy TechniquesSingle-cell and spatial transcriptomics

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An ocular glymphatic clearance system removes β-amyloid from the rodent eye

Wang, X., Lou, N., Eberhardt, A., Yang, Y., Kusk, P., Xu, Q., Förstera, B., Peng, S., Shi, M., Ladrón-de-Guevara, A., et al. (2020) · Science Translational Medicine

Glaucoma and retinal disordersCerebrospinal fluid and hydrocephalus

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Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body

Pan, C., Schoppe, O., Parra-Damas, A., Cai, R., Todorov, M. I., Gondi, G., von Neubeck, B., Böğürcü-Seidel, N., Seidel, S., Sleiman, K., et al. (2019) · Cell

Cell Image Analysis TechniquesAI in cancer detection

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Spatial proteomics in three-dimensional intact specimens

Bhatia, H. S., Brunner, A.-D., Öztürk, F., Kapoor, S., Rong, Z., Mai, H., Thielert, M., Ali, M., Al-Maskari, R., Paetzold, J. C., et al. (2022) · Cell

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

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Deep learning-enabled multi-organ segmentation in whole-body mouse scans

Schoppe, O., Pan, C., Coronel, J., Mai, H., Rong, Z., Todorov, M. I., Müskes, A., Navarro, F., Li, H., Ertürk, A., et al. (2020) · Nature Communications

Medical Image Segmentation TechniquesMedical Imaging and Analysis

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A guidebook for DISCO tissue clearing

Molbay, M., Kolabas, Z. I., Todorov, M. I., Ohn, T., & Ertürk, A. (2021) · Molecular Systems Biology

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

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Whole-mouse clearing and imaging at the cellular level with vDISCO

Cai, R., Kolabas, Z. I., Pan, C., Mai, H., Zhao, S., Kaltenecker, D., Voigt, F. F., Molbay, M., Ohn, T.-L., Vincke, C., et al. (2023) · Nature Protocols

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

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Virtual reality-empowered deep-learning analysis of brain cells

Kaltenecker, D., Al-Maskari, R., Negwer, M., Hoeher, L., Kofler, F., Zhao, S., Todorov, M., Rong, Z., Paetzold, J. C., Wiestler, B., et al. (2024) · Nature Methods

Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics

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The state of brain activity modulates cerebrospinal fluid transport

Miyakoshi, L. M., Stæger, F. F., Li, Q., Pan, C., Xie, L., Kang, H., Pavan, C., Dang, J., Sun, Q., Ertürk, A., et al. (2023) · Progress in Neurobiology

Cerebrospinal fluid and hydrocephalusIon Transport and Channel Regulation

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A deep-learning framework reveals whole-body perturbations at cell level

Kaltenecker, D., Horvath, I., Al-Maskari, R., Chen, Y., Kolabas, Z. I., Hoeher, L., Todorov, M., Minde, D.-P., Kapoor, S., Turhan, S. G., et al. (2026) · Nature

Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics

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