Lupardus, Patrick

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

Yadav, M., Jhunjhunwala, S., Phung, Q. T., Lupardus, P., Tanguay, J., Bumbaca, S., Franci, C., Cheung, T. K., Fritsche, J., Weinschenk, T., et al. (2014) · Nature

vaccines and immunoinformatics approachesCancer Immunotherapy and Biomarkers

Cited by 1,186

Novel antibody-antibiotic conjugate eliminates intracellular S. aureus

Lehar, S. M., Pillow, T., Xu, M., Staben, L., Kajihara, K. K., Vandlen, R., DePalatis, L., Raab, H., Hazenbos, W. L., Hiroshi Morisaki, J., et al. (2015) · Nature

Antimicrobial Resistance in StaphylococcusMonoclonal and Polyclonal Antibodies Research

Cited by 838

Kinase inhibition in autoimmunity and inflammation

Zarrin, A. A., Bao, K., Lupardus, P., & Vucic, D. (2021) · Nature Reviews Drug Discovery

NF-κB Signaling PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 431

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

Lauffer, B. E. L., Mintzer, R., Fong, R., Mukund, S., Tam, C., Zilberleyb, I., Flicke, B., Ritscher, A., Fedorowicz, G., Vallero, R., et al. (2013) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 429

Structure of the pseudokinase-kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition

Lupardus, P. J., Ultsch, M., Wallweber, H., Bir Kohli, P., Johnson, A. R., & Eigenbrot, C. (2014) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 229

Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells

Glassman, C. R., Mathiharan, Y. K., Jude, K. M., Su, L., Panova, O., Lupardus, P. J., Spangler, J. B., Ely, L. K., Thomas, C., Skiniotis, G., et al. (2021) · Cell

Cytokine Signaling Pathways and InteractionsImmune Cell Function and Interaction

Cited by 181

TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis

Sun, T., Huang, Z., Liang, W.-C., Yin, J., Lin, W. Y., Wu, J., Vernes, J.-M., Lutman, J., Caplazi, P., Jeet, S., et al. (2021) · Science Translational Medicine

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 134

Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities

Chang, D. J., Lupardus, P. J., & Cimprich, K. A. (2006) · Journal of Biological Chemistry

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 101

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase η on ATR checkpoint signaling

Bomgarden, R. D., Lupardus, P. J., Soni, D. V., Yee, M., Ford, J. M., & Cimprich, K. A. (2006) · The EMBO Journal

DNA Repair MechanismsNuclear Structure and Function

Cited by 87