Landthaler, Markus

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature

Circular RNAs in diseasesRNA Research and Splicing

Cited by 7,990

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A. O., Landthaler, M., et al. (2007) · Cell

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,626

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

Hafner, M., Landthaler, M., Burger, L., Khorshid, M., Hausser, J., Berninger, P., Rothballer, A., Ascano, M., Jungkamp, A.-C., Munschauer, M., et al. (2010) · Cell

RNA Research and SplicingRNA regulation and disease

Cited by 2,873

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., & Tuschl, T. (2004) · Molecular Cell

RNA Interference and Gene DeliveryMicroRNA in disease regulation

Cited by 2,052

Translation of CircRNAs

Pamudurti, N. R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., et al. (2017) · Molecular Cell

Circular RNAs in diseasesRNA and protein synthesis mechanisms

Cited by 1,810

Swarm Learning for decentralized and confidential clinical machine learning

Warnat-Herresthal, S., Schultze, H., Shastry, K. L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N. A., et al. (2021) · Nature

Privacy-Preserving Technologies in DataBlockchain Technology Applications and Security

Cited by 884

Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy

Paludan, C., Schmid, D., Landthaler, M., Vockerodt, M., Kube, D., Tuschl, T., & Münz, C. (2005) · Science

Autophagy in Disease and TherapyImmunotherapy and Immune Responses

Cited by 860

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

Lebedeva, S., Jens, M., Theil, K., Schwanhäusser, B., Selbach, M., Landthaler, M., & Rajewsky, N. (2011) · Molecular Cell

RNA Research and SplicingRNA regulation and disease

Cited by 716

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Wendisch, D., Dietrich, O., Mari, T., von Stillfried, S., Ibarra, I. L., Mittermaier, M., Mache, C., Chua, R. L., Knoll, R., Timm, S., et al. (2021) · Cell

COVID-19 Clinical Research StudiesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 528

Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms

Mino, T., Murakawa, Y., Fukao, A., Vandenbon, A., Wessels, H.-H., Ori, D., Uehata, T., Tartey, S., Akira, S., Suzuki, Y., et al. (2015) · Cell

RNA Research and SplicingRNA regulation and disease

Cited by 390

Virus-induced senescence is a driver and therapeutic target in COVID-19

Lee, S., Yu, Y., Trimpert, J., Benthani, F., Mairhofer, M., Richter-Pechanska, P., Wyler, E., Belenki, D., Kaltenbrunner, S., Pammer, M., et al. (2021) · Nature

Telomeres, Telomerase, and SenescenceCOVID-19 Clinical Research Studies

Cited by 350

DGCR8-dependent microRNA biogenesis is essential for skin development

Yi, R., Pasolli, H. A., Landthaler, M., Hafner, M., Ojo, T., Sheridan, R., Sander, C., O'Carroll, D., Stoffel, M., Tuschl, T., et al. (2009) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationDevelopmental Biology and Gene Regulation

Cited by 232

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L. J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., et al. (2022) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 218

Mechanism of Virus Attenuation by Codon Pair Deoptimization

Groenke, N., Trimpert, J., Merz, S., Conradie, A. M., Wyler, E., Zhang, H., Hazapis, O.-G., Rausch, S., Landthaler, M., Osterrieder, N., et al. (2020) · Cell Reports

RNA and protein synthesis mechanismsInfluenza Virus Research Studies

Cited by 85

In Vitro Kinase-to-Phosphosite Database (iKiP-DB) Predicts Kinase Activity in Phosphoproteomic Datasets

Mari, T., Mösbauer, K., Wyler, E., Landthaler, M., Drosten, C., & Selbach, M. (2022) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 70

Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis

De Santis, R., Alfano, V., de Turris, V., Colantoni, A., Santini, L., Garone, M. G., Antonacci, G., Peruzzi, G., Sudria-Lopez, E., Wyler, E., et al. (2019) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

Cited by 70

In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets

Mari, T., Mösbauer, K., Wyler, E., Landthaler, M., Drosten, C., & Selbach, M. (2022) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 70

A critical period of translational control during brain development at codon resolution

Harnett, D., Ambrozkiewicz, M. C., Zinnall, U., Rusanova, A., Borisova, E., Drescher, A. N., Couce-Iglesias, M., Villamil, G., Dannenberg, R., Imami, K., et al. (2022) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 68

A critical period of translational control during brain development at codon resolution

Harnett, D., Ambrozkiewicz, M. C., Zinnall, U., Rusanova, A., Borisova, E., Dannenberg, R., Imami, K., Münster-Wandowski, A., Fauler, B., Mielke, T., et al. (2021) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 67

Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit

Kraushar, M. L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M. C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C. H., et al. (2021) · Molecular Cell

RNA and protein synthesis mechanismsGenetics and Neurodevelopmental Disorders

Cited by 49

AI-guided pipeline for protein–protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Trepte, P., Secker, C., Olivet, J., Blavier, J., Kostova, S., Maseko, S. B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., et al. (2024) · Molecular Systems Biology

Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research

Cited by 35

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins

Zinnall, U., Milek, M., Minia, I., Vieira-Vieira, C. H., Müller, S., Mastrobuoni, G., Hazapis, O.-G., Del Giudice, S., Schwefel, D., Bley, N., et al. (2022) · Nature Communications

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 30

Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome

Boehm, V., Wallmeroth, D., Wulf, P. O., Popp, O., Teixeira Alves, L. G., Reinecke, L., Riedel, M., Wyler, E., Franitza, M., Becker, K., et al. (2025) · Molecular Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 23

Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated transcriptome in human cells

Boehm, V., Wallmeroth, D., Wulf, P. O., Alves, L. G. T., Popp, O., Riedel, M., Wyler, E., Franitza, M., Gerbracht, J. V., Becker, K., et al. (2024) · Molecular Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 23