Leclercq, Isabelle

Central Role of Pparα–Dependent Hepatic Lipid Turnover in Dietary Steatohepatitis in Mice

Ip, E., Farrell, G. C., Robertson, G., Hall, P., Kirsch, R., & Leclercq, I. (2003) · Hepatology

Liver Disease Diagnosis and TreatmentPeroxisome Proliferator-Activated Receptors

Cited by 476

Administration of the potent PPARα agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice

Ip, E., Farrell, G., Hall, P., Robertson, G., & Leclercq, I. (2004) · Hepatology

Liver Disease Diagnosis and TreatmentPeroxisome Proliferator-Activated Receptors

Cited by 383

Expression of miR-33 from an SREBP2 Intron Inhibits Cholesterol Export and Fatty Acid Oxidation*

Gerin, I., Clerbaux, L.-A., Haumont, O., Lanthier, N., Das, A. K., Burant, C. F., Leclercq, I. A., MacDougald, O. A., & Bommer, G. T. (2010) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 382

Liver Progenitor Cells Yield Functional Hepatocytes in Response to Chronic Liver Injury in Mice

Español–Suñer, R., Carpentier, R., Van Hul, N., Legry, V., Achouri, Y., Cordi, S., Jacquemin, P., Lemaigre, F., & Leclercq, I. A. (2012) · Gastroenterology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 356

Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis

Farrell, G., Schattenberg, J. M., Leclercq, I., Yeh, M. M., Goldin, R., Teoh, N., & Schuppan, D. (2019) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 313

Kupffer cells mediate leptin-induced liver fibrosis

Wang, J., Leclercq, I., Brymora, J. M., Xu, N., Ramezani–Moghadam, M., London, R. M., Brigstock, D., & George, J. (2009) · Gastroenterology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 210

Intestinal permeability, microbial translocation, changes in duodenal and fecal microbiota, and their associations with alcoholic liver disease progression in humans

Maccioni, L., Gao, B., Leclercq, S., Pirlot, B., Horsmans, Y., De Timary, P., Leclercq, I., Fouts, D., Schnabl, B., & Stärkel, P. (2020) · Gut Microbes

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 174

Muscle fat content is strongly associated with NASH: a longitudinal study in patients with morbid obesity

Nachit, M., Kwanten, W. J., Thissen, J.-P., Op De Beeck, B., Van Gaal, L., Vonghia, L., Verrijken, A., Driessen, A., Horsmans, Y., Francque, S., et al. (2021) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 114

Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury

Manco, R., Clerbaux, L.-A., Verhulst, S., Bou Nader, M., Sempoux, C., Ambroise, J., Bearzatto, B., Gala, J. L., Horsmans, Y., van Grunsven, L., et al. (2019) · Journal of Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 92

Myosteatosis rather than sarcopenia associates with non‐alcoholic steatohepatitis in non‐alcoholic fatty liver disease preclinical models

Nachit, M., De Rudder, M., Thissen, J., Schakman, O., Bouzin, C., Horsmans, Y., Vande Velde, G., & Leclercq, I. A. (2021) · Journal of Cachexia, Sarcopenia and Muscle

Liver Disease Diagnosis and TreatmentNutrition and Health in Aging

Cited by 82

Alcohol-associated bowel disease: new insights into pathogenesis

Maccioni, L., Fu, Y., Horsmans, Y., Leclercq, I., Stärkel, P., Kunos, G., & Gao, B. (2023) · eGastroenterology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 69

Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats

Leclercq, I. A. (2006) · Gut

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 67

Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment

Manco, R., Leclercq, I. A., & Clerbaux, L.-A. (2018) · International Journal of Molecular Sciences

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 36

Host Factors in Dysregulation of the Gut Barrier Function during Alcohol-Associated Liver Disease

Maccioni, L., Leclercq, I. A., Schnabl, B., & Stärkel, P. (2021) · International Journal of Molecular Sciences

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 31

Duodenal CD8+ T resident memory cell apoptosis contributes to gut barrier dysfunction and microbial translocation in early alcohol‐associated liver disease in humans

Maccioni, L., Loriot, A., Dewulf, J., Bommer, G., Horsmans, Y., Lanthier, N., Leclercq, I., Schnabl, B., & Stärkel, P. (2022) · Alimentary Pharmacology & Therapeutics

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 23

IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis

Czepukojc, B., Abuhaliema, A., Barghash, A., Tierling, S., Naß, N., Simon, Y., Körbel, C., Cadenas, C., van Hul, N., Sachinidis, A., et al. (2019) · Frontiers in Medicine

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 20

Serum keratin 18‐M65 levels detect progressive forms of alcohol‐associated liver disease in early noncirrhotic stages

Maccioni, L., Horsmans, Y., Leclercq, I., Schnabl, B., & Stärkel, P. (2023) · Alcohol: Clinical and Experimental Research

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 10