Rayner, Katey J.

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature

Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases

Cited by 4,026

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

Stewart, C. R., Stuart, L. M., Wilkinson, K., van Gils, J. M., Deng, J., Halle, A., Rayner, K. J., Boyer, L., Zhong, R., Frazier, W. A., et al. (2010) · Nature Immunology

Immune Response and InflammationAtherosclerosis and Cardiovascular Diseases

Cited by 1,513

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

Rayner, K. J., Suárez, Y., Dávalos, A., Parathath, S., Fitzgerald, M. L., Tamehiro, N., Fisher, E. A., Moore, K. J., & Fernández-Hernando, C. (2010) · Science

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 1,260

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

Sheedy, F. J., Grebe, A., Rayner, K. J., Kalantari, P., Ramkhelawon, B., Carpenter, S. B., Becker, C. E., Ediriweera, H. N., Mullick, A. E., Golenbock, D. T., et al. (2013) · Nature Immunology

Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases

Cited by 935

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

Rayner, K. J., Esau, C. C., Hussain, F. N., McDaniel, A. L., Marshall, S. M., van Gils, J. M., Ray, T. D., Sheedy, F. J., Goedeke, L., Liu, X., et al. (2011) · Nature

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 706

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

Rayner, K. J., Sheedy, F. J., Esau, C. C., Hussain, F. N., Temel, R. E., Parathath, S., van Gils, J. M., Rayner, A. J., Chang, A. N., Suarez, Y., et al. (2011) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 690

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

Dávalos, A., Goedeke, L., Smibert, P., Ramírez, C. M., Warrier, N. P., Andreo, U., Cirera-Salinas, D., Rayner, K., Suresh, U., Pastor-Pareja, J. C., et al. (2011) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationCholesterol and Lipid Metabolism

Cited by 670

MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

Ouimet, M., Ediriweera, H. N., Gundra, U. M., Sheedy, F. J., Ramkhelawon, B., Hutchison, S. B., Rinehold, K., van Solingen, C., Fullerton, M. D., Cecchini, K., et al. (2015) · Journal of Clinical Investigation

Atherosclerosis and Cardiovascular DiseasesMicroRNA in disease regulation

Cited by 394

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

van Gils, J. M., Derby, M. C., Fernandes, L. R., Ramkhelawon, B., Ray, T. D., Rayner, K. J., Parathath, S., Distel, E., Feig, J. L., Alvarez-Leite, J. I., et al. (2012) · Nature Immunology

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 365

Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Karunakaran, D., Geoffrion, M., Wei, L., Gan, W., Richards, L., Shangari, P., DeKemp, E. M., Beanlands, R. A., Perisic, L., Maegdefessel, L., et al. (2016) · Science Advances

Atherosclerosis and Cardiovascular DiseasesCell death mechanisms and regulation

Cited by 293

microRNA-33 regulates macrophage autophagy in atherosclerosis

Ouimet, M., Ediriweera, H., Afonso, M. S., Ramkhelawon, B., Singaravelu, R., Liao, X., Bandler, R. C., Rahman, K., Fisher, E. A., Rayner, K. J., et al. (2017) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cholesterol and Lipid MetabolismAutophagy in Disease and Therapy

Cited by 221

Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti-miR33 in atherosclerosis

Karunakaran, D., Thrush, A. B., Nguyen, M.-A., Richards, L., Geoffrion, M., Singaravelu, R., Ramphos, E., Shangari, P., Ouimet, M., Pezacki, J. P., et al. (2015) · Circulation Research

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 188

Injectable human recombinant collagen matrices limit adverse remodeling and improve cardiac function after myocardial infarction

McLaughlin, S., McNeill, B., Podrebarac, J., Hosoyama, K., Sedlakova, V., Cron, G., Smyth, D., Seymour, R., Goel, K., Liang, W., et al. (2019) · Nature Communications

Cardiac Fibrosis and RemodelingTissue Engineering and Regenerative Medicine

Cited by 153

IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis

Chen, H.-H., Keyhanian, K., Zhou, X., Vilmundarson, R. O., Almontashiri, N. A. M., Cruz, S. A., Pandey, N. R., Lerma Yap, N., Ho, T., Stewart, C. A., et al. (2015) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 91

LDL Receptor Pathway Regulation by miR-224 and miR-520d

Salerno, A. G., van Solingen, C., Scotti, E., Wanschel, A. C. B. A., Afonso, M. S., Oldebeken, S. R., Spiro, W., Tontonoz, P., Rayner, K. J., & Moore, K. J. (2020) · Frontiers in Cardiovascular Medicine

MicroRNA in disease regulationCholesterol and Lipid Metabolism

Cited by 33