Aebersold, Ruedi

Proteomic and interactomic insights into the molecular basis of cell functional diversity

Bludau, I., & Aebersold, R. (2020) · Nature Reviews Molecular Cell Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 297

Systems proteomics of liver mitochondria function

Williams, E. G., Wu, Y., Jha, P., Dubuis, S., Blattmann, P., Argmann, C. A., Houten, S. M., Amariuta, T., Wolski, W., Zamboni, N., et al. (2016) · Science

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 289

The chromosome-centric human proteome project for cataloging proteins encoded in the genome

Paik, Y.-K., Jeong, S.-K., Omenn, G. S., Uhlen, M., Hanash, S., Cho, S. Y., Lee, H.-J., Na, K., Choi, E.-Y., Yan, F., et al. (2012) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 288

Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population

Wu, Y., Williams, E. G., Dubuis, S., Mottis, A., Jovaisaite, V., Houten, S. M., Argmann, C. A., Faridi, P., Wolski, W., Kutalik, Z., et al. (2014) · Cell

Bioinformatics and Genomic NetworksGenetic Mapping and Diversity in Plants and Animals

Cited by 244

Independent evolution of the prochlorophyte and green plant chlorophyll a/b light-harvesting proteins

Roche, J. L., van der Staay, G. W. M., Partensky, F., Ducret, A., Aebersold, R., Li, R., Golden, S. S., Hiller, R. G., Wrench, P. M., Larkum, A. W. D., et al. (1996) · Proceedings of the National Academy of Sciences

Photosynthetic Processes and MechanismsLight effects on plants

Cited by 232

Comparative Functional Analysis of the Caenorhabditis elegans and Drosophila melanogaster Proteomes

Schrimpf, S. P., Weiss, M., Reiter, L., Ahrens, C. H., Jovanovic, M., Malmström, J., Brunner, E., Mohanty, S., Lercher, M. J., Hunziker, P. E., et al. (2009) · PLoS Biology

Advanced Proteomics Techniques and ApplicationsGenomics and Phylogenetic Studies

Cited by 229

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations

Ritz, D., Vuk, M., Kirchner, P., Bug, M., Schütz, S., Hayer, A., Bremer, S., Lusk, C., Baloh, R. H., Lee, H., et al. (2011) · Nature Cell Biology

Ubiquitin and proteasome pathwaysCaveolin-1 and cellular processes

Cited by 224

Absolute Proteome Composition and Dynamics during Dormancy and Resuscitation of Mycobacterium tuberculosis

Schubert, O. T., Ludwig, C., Kogadeeva, M., Zimmermann, M., Rosenberger, G., Gengenbacher, M., Gillet, L. C., Collins, B. C., Röst, H. L., Kaufmann, S. H. E., et al. (2015) · Cell Host & Microbe

Advanced Proteomics Techniques and ApplicationsTuberculosis Research and Epidemiology

Cited by 211

A high-stringency blueprint of the human proteome

Adhikari, S., Nice, E. C., Deutsch, E. W., Lane, L., Omenn, G. S., Pennington, S. R., Paik, Y.-K., Overall, C. M., Corrales, F. J., Cristea, I. M., et al. (2020) · Nature Communications

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 210

Quantitative measurements of N‐linked glycoproteins in human plasma by SWATH‐MS

Liu, Y., Hüttenhain, R., Surinova, S., Gillet, L. C., Mouritsen, J., Brunner, R., Navarro, P., & Aebersold, R. (2013) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsGlycosylation and Glycoproteins Research

Cited by 204

Statistical control of peptide and protein error rates in large-scale targeted data-independent acquisition analyses

Rosenberger, G., Bludau, I., Schmitt, U., Heusel, M., Hunter, C. L., Liu, Y., MacCoss, M. J., MacLean, B. X., Nesvizhskii, A. I., Pedrioli, P. G. A., et al. (2017) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 203

Impact of Alternative Splicing on the Human Proteome

Liu, Y., Gonzàlez-Porta, M., Santos, S., Brazma, A., Marioni, J. C., Aebersold, R., Venkitaraman, A. R., & Wickramasinghe, V. O. (2017) · Cell Reports

RNA Research and SplicingAdvanced Proteomics Techniques and Applications

Cited by 190

Applications of targeted proteomics in systems biology and translational medicine

Ebhardt, H. A., Root, A., Sander, C., & Aebersold, R. (2015) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 184

Peptide-Centric Proteome Analysis: An Alternative Strategy for the Analysis of Tandem Mass Spectrometry Data

Ting, Y. S., Egertson, J. D., Payne, S. H., Kim, S., MacLean, B., Käll, L., Aebersold, R., Smith, R. D., Noble, W. S., & MacCoss, M. J. (2015) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 175

Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells.

Wright, M. E., Tsai, M.-J., & Aebersold, R. (2003) · Molecular Endocrinology

Prostate Cancer Treatment and ResearchEstrogen and related hormone effects

Cited by 166

B cell antigen receptor cross-linking induces phosphorylation of the p21 ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein.

Saxton, T. M., van Oostveen, I., Bowtell, D., Aebersold, R., & Gold, M. R. (1994) · The Journal of Immunology

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 164

An automated pipeline for high-throughput label-free quantitative proteomics

Weisser, H., Nahnsen, S., Grossmann, J., Nilse, L., Quandt, A., Brauer, H., Sturm, M., Kenar, E., Kohlbacher, O., Aebersold, R., et al. (2013) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 160

Visual proteomics of the human pathogen Leptospira interrogans

Beck, M., Malmström, J. A., Lange, V., Schmidt, A., Deutsch, E. W., & Aebersold, R. (2009) · Nature Methods

Advanced Electron Microscopy Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 156

Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

Celis-Gutierrez, J., Blattmann, P., Zhai, Y., Jarmuzynski, N., Ruminski, K., Grégoire, C., Ounoughene, Y., Fiore, F., Aebersold, R., Roncagalli, R., et al. (2019) · Cell Reports

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 154

Mass spectrometry supported determination of protein complex structure

Walzthoeni, T., Leitner, A., Stengel, F., & Aebersold, R. (2013) · Current Opinion in Structural Biology

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 146

Complex‐centric proteome profiling by SEC‐SWATH‐MS

Heusel, M., Bludau, I., Rosenberger, G., Hafen, R., Frank, M., Banaei‐Esfahani, A., van Drogen, A., Collins, B. C., Gstaiger, M., & Aebersold, R. (2019) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 141

Systematic proteome and proteostasis profiling in human trisomy 21 fibroblast cells

Liu, Y., Borel, C., Li, L., Müller, T., Williams, E. G., Germain, P.-L., Buljan, M., Sajic, T., Boersema, P. J., Shao, W., et al. (2017) · Nature Communications

Down syndrome and intellectual disability researchAdvanced Proteomics Techniques and Applications

Cited by 141

Complex-centric proteome profiling by SEC-SWATH-MS

Heusel, M., Bludau, I., Rosenberger, G., Hafen, R., Frank, M., Banaei-Esfahani, A., Collins, B., Gstaiger, M., & Aebersold, R. (2018) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 141

The Calcineurin Signaling Network Evolves via Conserved Kinase-Phosphatase Modules that Transcend Substrate Identity

Goldman, A., Roy, J., Bodenmiller, B., Wanka, S., Landry, C. R., Aebersold, R., & Cyert, M. S. (2014) · Molecular Cell

Signaling Pathways in DiseaseProtein Tyrosine Phosphatases

Cited by 109