Aebersold, Ruedi

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

Trushina, E., Dyer, R. B., Badger, J. D., Ure, D., Eide, L., Tran, D. D., Vrieze, B. T., Legendre-Guillemin, V., McPherson, P. S., Mandavilli, B. S., et al. (2004) · Molecular and Cellular Biology

Genetic Neurodegenerative DiseasesHereditary Neurological Disorders

Cited by 520

Development and validation of a spectral library searching method for peptide identification from MS/MS

Lam, H., Deutsch, E. W., Eddes, J. S., Eng, J. K., King, N., Stein, S. E., & Aebersold, R. (2007) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 517

CTCF physically links cohesin to chromatin

Rubio, E. D., Reiss, D. J., Welcsh, P. L., Disteche, C. M., Filippova, G. N., Baliga, N. S., Aebersold, R., Ranish, J. A., & Krumm, A. (2008) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsDNA Repair Mechanisms

Cited by 511

Proteome organization in a genome-reduced bacterium

Kühner, S., van Noort, V., Betts, M. J., Leo-Macias, A., Batisse, C., Rode, M., Yamada, T., Maier, T., Bader, S., Beltran-Alvarez, P., et al. (2009) · Science

Bacterial Genetics and BiotechnologyMicrobial infections and disease research

Cited by 471

Mass spectrometry in high-throughput proteomics: ready for the big time

Nilsson, T., Mann, M., Aebersold, R., Yates, J. R., Bairoch, A., & Bergeron, J. J. M. (2010) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 470

Rewiring of Genetic Networks in Response to DNA Damage

Bandyopadhyay, S., Mehta, M., Kuo, D., Sung, M.-K., Chuang, R., Jaehnig, E. J., Bodenmiller, B., Licon, K., Copeland, W., Shales, M., et al. (2010) · Science

Fungal and yeast genetics researchDNA Repair Mechanisms

Cited by 447

Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans

Malmström, J., Beck, M., Schmidt, A., Lange, V., Deutsch, E. W., & Aebersold, R. (2009) · Nature

Advanced Proteomics Techniques and ApplicationsLeptospirosis research and findings

Cited by 421

A repository of assays to quantify 10,000 human proteins by SWATH-MS

Rosenberger, G., Koh, C. C., Guo, T., Röst, H. L., Kouvonen, P., Collins, B. C., Heusel, M., Liu, Y., Caron, E., Vichalkovski, A., et al. (2014) · Scientific Data

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 413

Proteomics Analysis of Cellular Response to Oxidative Stress

Rabilloud, T., Heller, M., Gasnier, F., Luche, S., Rey, C., Aebersold, R., Benahmed, M., Louisot, P., & Lunardi, J. (2002) · Journal of Biological Chemistry

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 393

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps

Guo, T., Kouvonen, P., Koh, C. C., Gillet, L. C., Wolski, W. E., Röst, H. L., Rosenberger, G., Collins, B. C., Blum, L. C., Gillessen, S., et al. (2015) · Nature Medicine

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 376

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

Goudreault, M., D'Ambrosio, L. M., Kean, M. J., Mullin, M. J., Larsen, B. G., Sanchez, A., Chaudhry, S., Chen, G. I., Sicheri, F., Nesvizhskii, A. I., et al. (2009) · Molecular & Cellular Proteomics

Protein Kinase Regulation and GTPase SignalingVascular Malformations Diagnosis and Treatment

Cited by 359

The human proteome project: current state and future direction

Legrain, P., Aebersold, R., Archakov, A., Bairoch, A., Bala, K., Beretta, L., Bergeron, J., Borchers, C. H., Corthals, G. L., Costello, C. E., et al. (2011) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 352

A multicenter study benchmarks software tools for label-free proteome quantification

Navarro, P., Kuharev, J., Gillet, L. C., Bernhardt, O. M., MacLean, B., Röst, H. L., Tate, S. A., Tsou, C.-C., Reiter, L., Distler, U., et al. (2016) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 346

Multi-omic measurements of heterogeneity in HeLa cells across laboratories

Liu, Y., Mi, Y., Mueller, T., Kreibich, S., Williams, E. G., Van Drogen, A., Borel, C., Frank, M., Germain, P.-L., Bludau, I., et al. (2019) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsViral Infectious Diseases and Gene Expression in Insects

Cited by 338

On the Development of Plasma Protein Biomarkers

Surinova, S., Schiess, R., Hüttenhain, R., Cerciello, F., Wollscheid, B., & Aebersold, R. (2011) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 334

Quantitative variability of 342 plasma proteins in a human twin population

Liu, Y., Buil, A., Collins, B. C., Gillet, L. C., Blum, L. C., Cheng, L., Vitek, O., Mouritsen, J., Lachance, G., Spector, T. D., et al. (2015) · Molecular Systems Biology

Genetic Associations and EpidemiologyAdvanced Proteomics Techniques and Applications

Cited by 328

Mass Spectrometry Applied to Bottom-Up Proteomics: Entering the High-Throughput Era for Hypothesis Testing

Gillet, L. C., Leitner, A., & Aebersold, R. (2016) · Annual Review of Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 323

Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

Lambert, J.-P., Ivosev, G., Couzens, A. L., Larsen, B., Taipale, M., Lin, Z.-Y., Zhong, Q., Lindquist, S., Vidal, M., Aebersold, R., et al. (2013) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 318

A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis

Picotti, P., Clément-Ziza, M., Lam, H., Campbell, D. S., Schmidt, A., Deutsch, E. W., Röst, H., Sun, Z., Rinner, O., Reiter, L., et al. (2013) · Nature

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 318

Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system

Collins, B. C., Gillet, L. C., Rosenberger, G., Röst, H. L., Vichalkovski, A., Gstaiger, M., & Aebersold, R. (2013) · Nature Methods

Advanced Proteomics Techniques and Applications14-3-3 protein interactions

Cited by 314

Protein Identification False Discovery Rates for Very Large Proteomics Data Sets Generated by Tandem Mass Spectrometry

Reiter, L., Claassen, M., Schrimpf, S. P., Jovanovic, M., Schmidt, A., Buhmann, J. M., Hengartner, M. O., & Aebersold, R. (2009) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 312

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis

Cortes, T., Schubert, O. T., Rose, G., Arnvig, K. B., Comas, I., Aebersold, R., & Young, D. B. (2013) · Cell Reports

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 310

Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome

Kusebauch, U., Campbell, D. S., Deutsch, E. W., Chu, C. S., Spicer, D. A., Brusniak, M.-Y., Slagel, J., Sun, Z., Stevens, J., Grimes, B., et al. (2016) · Cell

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 310

Quantification of mRNA and protein and integration with protein turnover in a bacterium

Maier, T., Schmidt, A., Güell, M., Kühner, S., Gavin, A., Aebersold, R., & Serrano, L. (2011) · Molecular Systems Biology

Bacterial Genetics and BiotechnologyGene Regulatory Network Analysis

Cited by 297