Zweier, Jay L.

A model for p53-induced apoptosis

Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., & Vogelstein, B. (1997) · Nature

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 2,500

Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

Irani, K., Xia, Y., Zweier, J. L., Sollott, S. J., Der, C. J., Fearon, E. R., Sundaresan, M., Finkel, T., & Goldschmidt-Clermont, P. J. (1997) · Science

Protein Kinase Regulation and GTPase SignalingRedox biology and oxidative stress

Cited by 1,588

Reactive Oxygen Species (Ros-Induced) Ros Release

Zorov, D. B., Filburn, C. R., Klotz, L.-O., Zweier, J. L., & Sollott, S. J. (2000) · The Journal of Experimental Medicine

Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion

Cited by 1,412

Enzyme-independent formation of nitric oxide in biological tissues

Zweier, J. L., Wang, P., Samouilov, A., & Kuppusamy, P. (1995) · Nature Medicine

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 788

Superoxide Generation from Endothelial Nitric-oxide Synthase

Xia, Y., Tsai, A.-L., Berka, V., & Zweier, J. L. (1998) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsMetal-Catalyzed Oxygenation Mechanisms

Cited by 705

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

Chan, S. Y., Zhang, Y.-Y., Hemann, C., Mahoney, C. E., Zweier, J. L., & Loscalzo, J. (2009) · Cell Metabolism

MicroRNA in disease regulationMitochondrial Function and Pathology

Cited by 702

Nitrate and nitrite in biology, nutrition and therapeutics

Lundberg, J. O., Gladwin, M. T., Ahluwalia, A., Benjamin, N., Bryan, N. S., Butler, A., Cabrales, P., Fago, A., Feelisch, M., Ford, P. C., et al. (2009) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 617

Stoichiometric and site characteristics of the binding of iron to human transferrin

Aisen, P., Leibman, A., & Zweier, J. (1978) · Journal of Biological Chemistry

Iron Metabolism and DisordersHemoglobin structure and function

Cited by 601

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

Chen, C.-A., Wang, T.-Y., Varadharaj, S., Reyes, L. A., Hemann, C., Talukder, M. A. H., Chen, Y.-R., Druhan, L. J., & Zweier, J. L. (2010) · Nature

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 594

Nitrite as Regulator of Hypoxic Signaling in Mammalian Physiology

van Faassen, E. E., Bahrami, S., Feelisch, M., Hogg, N., Kelm, M., Kim‐Shapiro, D. B., Kozlov, A. V., Li, H., Lundberg, J. O., Mason, R., et al. (2009) · Medicinal Research Reviews

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 435

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide

Yan, S. D., Yan, S. F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M. A., Perry, G., Godman, G. C., Nawroth, P., et al. (1995) · Nature Medicine

Alzheimer's disease research and treatmentsAdvanced Glycation End Products research

Cited by 406

Inducible Nitric-oxide Synthase Generates Superoxide from the Reductase Domain

Xia, Y., Roman, L. J., Masters, B. S. S., & Zweier, J. L. (1998) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsMetal-Catalyzed Oxygenation Mechanisms

Cited by 388

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Tarragó, M. G., Chini, C. C. S., Kanamori, K. S., Warner, G. M., Caride, A., de Oliveira, G. C., Rud, M., Samani, A., Hein, K. Z., Huang, R., et al. (2018) · Cell Metabolism

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 384

Noninvasive measurement of anatomic structure and intraluminal oxygenation in the gastrointestinal tract of living mice with spatial and spectral EPR imaging

He, G., Shankar, R. A., Chzhan, M., Samouilov, A., Kuppusamy, P., & Zweier, J. L. (1999) · Proceedings of the National Academy of Sciences

Electron Spin Resonance StudiesElectrical and Bioimpedance Tomography

Cited by 383

Non-Enzymatic Nitric Oxide Synthesis in Biological Systems

Zweier, J. L., Samouilov, A., & Kuppusamy, P. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 363

Characterization of the Magnitude and Kinetics of Xanthine Oxidase-catalyzed Nitrite Reduction

Li, H., Samouilov, A., Liu, X., & Zweier, J. L. (2001) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsGout, Hyperuricemia, Uric Acid

Cited by 280

Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes

Josephson, R. A., Silverman, H. S., Lakatta, E. G., Stern, M. D., & Zweier, J. L. (1991) · Journal of Biological Chemistry

Cardiac Ischemia and ReperfusionCardiac electrophysiology and arrhythmias

Cited by 272

On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

Muscoli, C., Cuzzocrea, S., Riley, D. P., Zweier, J. L., Thiemermann, C., Wang, Z., & Salvemini, D. (2003) · British Journal of Pharmacology

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 271

Nitric Oxide Production from Nitrite Occurs Primarily in Tissues Not in the Blood

Li, H., Cui, H., Kundu, T. K., Alzawahra, W., & Zweier, J. L. (2008) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 269

Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy

Zweier, J. L., Wang, P., & Kuppusamy, P. (1995) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 244

Myocardial ischemia results in tetrahydrobiopterin (BH 4 ) oxidation with impaired endothelial function ameliorated by BH 4

Dumitrescu, C., Biondi, R., Xia, Y., Cardounel, A. J., Druhan, L. J., Ambrosio, G., & Zweier, J. L. (2007) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 192

Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues

Li, H., Samouilov, A., Liu, X., & Zweier, J. L. (2003) · Biochemistry

Nitric Oxide and Endothelin EffectsGout, Hyperuricemia, Uric Acid

Cited by 180

Decreased nitric-oxide synthase activity causes impaired endothelium-dependent relaxation in the postischemic heart

Giraldez, R. R., Panda, A., Xia, Y., Sanders, S. P., & Zweier, J. L. (1997) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 180

Evaluation of the role of xanthine oxidase in myocardial reperfusion injury.

Thompson-Gorman, S. L., & Zweier, J. L. (1990) · Journal of Biological Chemistry

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 168