Zweier, Jay L.

Novel particulate spin probe for targeted determination of oxygen in cells and tissues

Pandian, R. P., Parinandi, N. L., Ilangovan, G., Zweier, J. L., & Kuppusamy, P. (2003) · Free Radical Biology and Medicine

Electron Spin Resonance StudiesAnalytical Chemistry and Sensors

Cited by 150

Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation

Li, H., Samouilov, A., Liu, X., & Zweier, J. L. (2004) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsGout, Hyperuricemia, Uric Acid

Cited by 146

Regulation of xanthine oxidase by nitric oxide and peroxynitrite

Lee, C.-I., Liu, X., & Zweier, J. L. (2000) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 140

Measurement and Characterization of Superoxide Generation in Microglial Cells: Evidence for an NADPH Oxidase-Dependent Pathway

Sankarapandi, S., Zweier, J. L., Mukherjee, G., Quinn, M. T., & Huso, D. L. (1998) · Archives of Biochemistry and Biophysics

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 136

Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall

Zweier, J. L., Li, H., Samouilov, A., & Liu, X. (2010) · Nitric Oxide

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 132

Characterization of the Mechanism and Magnitude of Cytoglobin-mediated Nitrite Reduction and Nitric Oxide Generation under Anaerobic Conditions

Li, H., Hemann, C., Abdelghany, T. M., El-Mahdy, M. A., & Zweier, J. L. (2012) · Journal of Biological Chemistry

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 132

Hypoxia and Reoxygenation Induce Endothelial Nitric Oxide Synthase Uncoupling in Endothelial Cells through Tetrahydrobiopterin Depletion and S-Glutathionylation

De Pascali, F., Hemann, C., Samons, K., Chen, C.-A., & Zweier, J. L. (2014) · Biochemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 131

Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite

Li, H., Kundu, T. K., & Zweier, J. L. (2009) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsPharmacogenetics and Drug Metabolism

Cited by 126

Cardiac Myocyte–Specific Expression of Inducible Nitric Oxide Synthase Protects Against Ischemia/Reperfusion Injury by Preventing Mitochondrial Permeability Transition

West, M. B., Rokosh, G., Obal, D., Velayutham, M., Xuan, Y.-T., Hill, B. G., Keith, R. J., Schrader, J., Guo, Y., Conklin, D. J., et al. (2008) · Circulation

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 121

Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall

Alzawahra, W. F., Talukder, M. A. H., Liu, X., Samouilov, A., & Zweier, J. L. (2008) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 111

Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall

Liu, X., El-Mahdy, M. A., Boslett, J., Varadharaj, S., Hemann, C., Abdelghany, T. M., Ismail, R. S., Little, S. C., Zhou, D., Thuy, L. T. T., et al. (2017) · Nature Communications

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 105

Regulation of eNOS-Derived Superoxide by Endogenous Methylarginines

Druhan, L. J., Forbes, S. P., Pope, A. J., Chen, C.-A., Zweier, J. L., & Cardounel, A. J. (2008) · Biochemistry

Nitric Oxide and Endothelin EffectsCancer-related gene regulation

Cited by 104

Role of dietary antioxidants in the preservation of vascular function and the modulation of health and disease

Varadharaj, S., Kelly, O. J., Khayat, R. N., Kumar, P. S., Ahmed, N., & Zweier, J. L. (2017) · Frontiers in Cardiovascular Medicine

Nitric Oxide and Endothelin EffectsAntioxidant Activity and Oxidative Stress

Cited by 101

Aldehyde Oxidase Functions as a Superoxide Generating NADH Oxidase: An Important Redox Regulated Pathway of Cellular Oxygen Radical Formation

Kundu, T. K., Velayutham, M., & Zweier, J. L. (2012) · Biochemistry

Redox biology and oxidative stressMetal-Catalyzed Oxygenation Mechanisms

Cited by 93

Characterization of superoxide production from aldehyde oxidase: An important source of oxidants in biological tissues

Kundu, T. K., Hille, R., Velayutham, M., & Zweier, J. L. (2007) · Archives of Biochemistry and Biophysics

Redox biology and oxidative stressMetal-Catalyzed Oxygenation Mechanisms

Cited by 83

Characterization of the Mechanism of Cytochrome P450 Reductase-Cytochrome P450-mediated Nitric Oxide and Nitrosothiol Generation from Organic Nitrates

Li, H., Liu, X., Cui, H., Chen, Y.-R., Cardounel, A. J., & Zweier, J. L. (2006) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsPharmacogenetics and Drug Metabolism

Cited by 74

Redox Modulation of Endothelial Nitric Oxide Synthase by Glutaredoxin-1 through Reversible Oxidative Post-Translational Modification

Chen, C.-A., De Pascali, F., Basye, A., Hemann, C., & Zweier, J. L. (2013) · Biochemistry

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 71

Luteolinidin Protects the Postischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H)

Boslett, J., Hemann, C., Zhao, Y. J., Lee, H.-C., & Zweier, J. L. (2017) · The Journal of Pharmacology and Experimental Therapeutics

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 69

Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals

Zweier, J. L., Duke, S. S., Kuppusamy, P., Sylvester, J. T., & Gabrielson, E. W. (1989) · FEBS Letters

Redox biology and oxidative stressElectron Spin Resonance Studies

Cited by 67

Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion

Boslett, J., Hemann, C., Christofi, F. L., & Zweier, J. L. (2018) · American Journal of Physiology-Cell Physiology

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 65

Trityl-based EPR probe with enhanced sensitivity to oxygen

Bobko, A. A., Dhimitruka, I., Eubank, T. D., Marsh, C. B., Zweier, J. L., & Khramtsov, V. V. (2009) · Free Radical Biology and Medicine

Electron Spin Resonance StudiesMolecular Sensors and Ion Detection

Cited by 63

Antioxidants and phase 2 enzymes in cardiomyocytes: Chemical inducibility and chemoprotection against oxidant and simulated ischemia-reperfusion injury

Cao, Z., Zhu, H., Zhang, L., Zhao, X., Zweier, J. L., & Li, Y. (2006) · Experimental Biology and Medicine

Genomics, phytochemicals, and oxidative stressCardiac Ischemia and Reperfusion

Cited by 56

Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c

Chen, Y.-R., Chen, C.-L., Liu, X., Li, H., Zweier, J. L., & Mason, R. P. (2004) · Free Radical Biology and Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 51

Electrochemical preparation and EPR studies of lithium phthalocyanine. 3. Measurements of oxygen concentration in tissues and biochemical reactions

Ilangovan, G., Li, H., Zweier, J. L., & Kuppusamy, P. (2001) · The Journal of Physical Chemistry B

Electron Spin Resonance StudiesAnalytical Chemistry and Sensors

Cited by 51