Clegg, Deborah J.

The role of estrogens in control of energy balance and glucose homeostasis

Mauvais-Jarvis, F., Clegg, D. J., & Hevener, A. L. (2013) · Endocrine Reviews

Estrogen and related hormone effectsRegulation of Appetite and Obesity

Cited by 1,329

The sexual dimorphism of obesity

Palmer, B. F., & Clegg, D. J. (2015) · Molecular and Cellular Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 919

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

Holland, W. L., Bikman, B. T., Wang, L.-P., Yuguang, G., Sargent, K. M., Bulchand, S., Knotts, T. A., Shui, G., Clegg, D. J., Wenk, M. R., et al. (2011) · Journal of Clinical Investigation

Sphingolipid Metabolism and SignalingAdipokines, Inflammation, and Metabolic Diseases

Cited by 705

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

Xu, Y., Nedungadi, T. P., Zhu, L., Sobhani, N., Irani, B. G., Davis, K. E., Zhang, X., Zou, F., Gent, L. M., Hahner, L. D., et al. (2011) · Cell Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 597

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

Posey, K. A., Clegg, D. J., Printz, R. L., Byun, J., Morton, G. J., Vivekanandan-Giri, A., Pennathur, S., Baskin, D. G., Heinecke, J. W., Woods, S. C., et al. (2009) · American Journal of Physiology-Endocrinology and Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 586

Gonadal Hormones Determine Sensitivity to Central Leptin and Insulin

Clegg, D. J., Brown, L. M., Woods, S. C., & Benoit, S. C. (2006) · Diabetes

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 552

Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Clase, C. M., Carrero, J.-J., Ellison, D. H., Grams, M. E., Hemmelgarn, B. R., Jardine, M. J., Kovesdy, C. P., Kline, G. A., Lindner, G., Obrador, G. T., et al. (2020) · Kidney International

Potassium and Related DisordersParathyroid Disorders and Treatments

Cited by 498

Insulin Activation of Phosphatidylinositol 3-Kinase in the Hypothalamic Arcuate Nucleus

Niswender, K. D., Morrison, C. D., Clegg, D. J., Olson, R., Baskin, D. G., Myers, M. G., Seeley, R. J., & Schwartz, M. W. (2003) · Diabetes

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 476

The Catabolic Action of Insulin in the Brain Is Mediated by Melanocortins

Benoit, S. C., Air, E. L., Coolen, L. M., Strauss, R., Jackman, A., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2002) · The Journal of Neuroscience

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 417

Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity

Haas, E., Bhattacharya, I., Brailoiu, E., Damjanović, M., Brailoiu, G. C., Gao, X., Mueller-Guerre, L., Marjon, N. A., Gut, A., Minotti, R., et al. (2009) · Circulation Research

Estrogen and related hormone effectsReceptor Mechanisms and Signaling

Cited by 373

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents

Benoit, S. C., Kemp, C. J., Elias, C. F., Abplanalp, W., Herman, J. P., Migrenne, S., Lefevre, A.-L., Cruciani-Guglielmacci, C., Magnan, C., Yu, F., et al. (2009) · Journal of Clinical Investigation

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 351

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Kilpeläinen, T. O., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 335

Differential Sensitivity to Central Leptin and Insulin in Male and Female Rats

Clegg, D. J., Riedy, C. A., Smith, K. A. B., Benoit, S. C., & Woods, S. C. (2003) · Diabetes

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 332

Central effects of estradiol in the regulation of food intake, body weight, and adiposity

Brown, L. M., & Clegg, D. J. (2010) · The Journal of Steroid Biochemistry and Molecular Biology

Regulation of Appetite and ObesityEstrogen and related hormone effects

Cited by 331

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat

Davis, J. F., Tracy, A. L., Schurdak, J. D., Tschöp, M. H., Lipton, J. W., Clegg, D. J., & Benoit, S. C. (2008) · Behavioral Neuroscience

Neurotransmitter Receptor Influence on BehaviorRegulation of Appetite and Obesity

Cited by 307

The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis

Davis, K. E., D. Neinast, M., Sun, K., M. Skiles, W., D. Bills, J., A. Zehr, J., Zeve, D., D. Hahner, L., W. Cox, D., M. Gent, L., et al. (2013) · Molecular Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 278

Sexual differences in the control of energy homeostasis

Shi, H., Seeley, R. J., & Clegg, D. J. (2009) · Frontiers in Neuroendocrinology

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 242

Physiology and Pathophysiology of Potassium Homeostasis: Core Curriculum 2019

Palmer, B. F., & Clegg, D. J. (2019) · American Journal of Kidney Diseases

Potassium and Related DisordersIon Transport and Channel Regulation

Cited by 215

A microarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice

Grove, K. L., Fried, S. K., Greenberg, A. S., Xiao, X. Q., & Clegg, D. J. (2010) · International Journal of Obesity

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 208

Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice

Park, C. J., Zhao, Z., Glidewell-Kenney, C., Lazic, M., Chambon, P., Krust, A., Weiss, J., Clegg, D. J., Dunaif, A., Jameson, J. L., et al. (2011) · Journal of Clinical Investigation

Estrogen and related hormone effectsRegulation of Appetite and Obesity

Cited by 162

Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice

Brown, L. M., Clegg, D. J., Benoit, S. C., & Woods, S. C. (2006) · Physiology & Behavior

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 139

The role of hypothalamic estrogen receptors in metabolic regulation

Frank, A., Brown, L. M., & Clegg, D. J. (2014) · Frontiers in Neuroendocrinology

Regulation of Appetite and ObesityEstrogen and related hormone effects

Cited by 128

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

Stout, M. B., Steyn, F. J., Jurczak, M. J., Camporez, J.-P. G., Zhu, Y., Hawse, J. R., Jurk, D., Palmer, A. K., Xu, M., Pirtskhalava, T., et al. (2017) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Adipose Tissue and MetabolismHormonal and reproductive studies

Cited by 119