Clish, Clary B.

Identification and Application of Gene Expression Signatures Associated with Lifespan Extension

Tyshkovskiy, A., Bozaykut, P., Borodinova, A. A., Gerashchenko, M. V., Ables, G. P., Garratt, M., Khaitovich, P., Clish, C. B., Miller, R. A., & Gladyshev, V. N. (2019) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 167

Revealing disease-associated pathways by network integration of untargeted metabolomics

Pirhaji, L., Milani, P., Leidl, M., Curran, T., Avila-Pacheco, J., Clish, C. B., White, F. M., Saghatelian, A., & Fraenkel, E. (2016) · Nature Methods

Bioinformatics and Genomic NetworksMetabolomics and Mass Spectrometry Studies

Cited by 167

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Rusu, V., Hoch, E., Mercader, J. M., Tenen, D. E., Gymrek, M., Hartigan, C. R., DeRan, M., von Grotthuss, M., Fontanillas, P., Spooner, A., et al. (2017) · Cell

Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer

Cited by 152

Altered exocrine function can drive adipose wasting in early pancreatic cancer

Danai, L. V., Babic, A., Rosenthal, M. H., Dennstedt, E. A., Muir, A., Lien, E. C., Mayers, J. R., Tai, K., Lau, A. N., Jones-Sali, P., et al. (2018) · Nature

Pancreatic and Hepatic Oncology ResearchNutrition and Health in Aging

Cited by 141

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Finley, L. W. S., Lee, J., Souza, A., Desquiret-Dumas, V., Bullock, K., Rowe, G. C., Procaccio, V., Clish, C. B., Arany, Z., & Haigis, M. C. (2012) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 102

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease

Katz, D. H., Tahir, U. A., Bick, A. G., Pampana, A., Ngo, D., Benson, M. D., Yu, Z., Robbins, J. M., Chen, Z.-Z., Cruz, D. E., et al. (2022) · Circulation

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 92

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

Ma, S., Upneja, A., Galecki, A., Tsai, Y.-M., Burant, C. F., Raskind, S., Zhang, Q., Zhang, Z. D., Seluanov, A., Gorbunova, V., et al. (2016) · eLife

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 89

Primer on Medical Genomics Part XIV: Introduction to Systems Biology—A New Approach to Understanding Disease and Treatment

Morel, N. M., Holland, J. M., van der Greef, J., Marple, E. W., Clish, C., Loscalzo, J., & Naylor, S. (2004) · Mayo Clinic Proceedings

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 71

The HERITAGE family study: a review of the effects of exercise training on cardiometabolic health, with insights into molecular transducers

SARZYNSKI, M. A., RICE, T. K., DESPRÉS, J.-P., PÉRUSSE, L., TREMBLAY, A., STANFORTH, P. R., TCHERNOF, A., BARBER, J. L., FALCIANI, F., CLISH, C., et al. (2022) · Medicine & Science in Sports & Exercise

Cardiovascular and exercise physiologyGenetics and Physical Performance

Cited by 62

Vaginal Lactobacillus fatty acid response mechanisms reveal a metabolite-targeted strategy for bacterial vaginosis treatment

Zhu, M., Frank, M. W., Radka, C. D., Jeanfavre, S., Xu, J., Tse, M. W., Pacheco, J. A., Kim, J. S., Pierce, K., Deik, A., et al. (2024) · Cell

Reproductive tract infections researchGut microbiota and health

Cited by 61

Endospores and other lysis-resistant bacteria comprise a widely shared core community within the human microbiota

Kearney, S. M., Gibbons, S. M., Poyet, M., Gurry, T., Bullock, K., Allegretti, J. R., Clish, C. B., & Alm, E. J. (2018) · The ISME Journal

Gut microbiota and healthClostridium difficile and Clostridium perfringens research

Cited by 59

Associations between plasma branched-chain amino acids, β-aminoisobutyric acid and body composition

Rietman, A., Stanley, T. L., Clish, C., Mootha, V., Mensink, M., Grinspoon, S. K., & Makimura, H. (2016) · Journal of Nutritional Science

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 38

Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population

Semova, I., Levenson, A. E., Krawczyk, J., Bullock, K., Williams, K. A., Wadwa, R. P., Shah, A. S., Khoury, P. R., Kimball, T. R., Urbina, E. M., et al. (2019) · Journal of Clinical Lipidology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 33

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2024) · eLife

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 33

Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study

Yu, E., Ruiz-Canela, M., Hu, F. B., Clish, C. B., Corella, D., Salas-Salvadó, J., Hruby, A., Fitó, M., Liang, L., Toledo, E., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism

Nutritional Studies and DietMetabolomics and Mass Spectrometry Studies

Cited by 30

Cross-ancestry comparison of aptamer and antibody protein measures

Nicholas, J. C., Katz, D. H., Tahir, U. A., Debban, C. L., Aguet, F., Blackwell, T., Bowler, R. P., Broadaway, K. A., Chen, J., Clish, C. B., et al. (2026) · Nature Communications

Genetic Associations and EpidemiologyAdvanced Biosensing Techniques and Applications

Cited by 13

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J. E., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 2

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J. E., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2024) · eLife

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 0