Darlington, Gretchen J.

Dnmt3a is essential for hematopoietic stem cell differentiation

Challen, G. A., Sun, D., Jeong, M., Luo, M., Jelinek, J., Berg, J. S., Bock, C., Vasanthakumar, A., Gu, H., Xi, Y., et al. (2012) · Nature Genetics

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

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Impaired Energy Homeostasis in C/EBPα Knockout Mice

Wang, N.-D., Finegold, M. J., Bradley, A., Ou, C. N., Abdelsayed, S. V., Wilde, M. D., Taylor, L. R., Wilson, D. R., & Darlington, G. J. (1995) · Science

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 929

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

Zhang, D.-E., Zhang, P., Wang, N.-D., Hetherington, C. J., Darlington, G. J., & Tenen, D. G. (1997) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchBlood disorders and treatments

Cited by 910

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

Sun, D., Luo, M., Jeong, M., Rodriguez, B., Xia, Z., Hannah, R., Wang, H., Le, T., Faull, K. F., Chen, R., et al. (2014) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

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Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells

Challen, G. A., Sun, D., Mayle, A., Jeong, M., Luo, M., Rodriguez, B., Mallaney, C., Celik, H., Yang, L., Xia, Z., et al. (2014) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 354

Large conserved domains of low DNA methylation maintained by Dnmt3a

Jeong, M., Sun, D., Luo, M., Huang, Y., Challen, G. A., Rodriguez, B., Zhang, X., Chavez, L., Wang, H., Hannah, R., et al. (2014) · Nature Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 324

Alterations in xenobiotic metabolism in the long‐lived Little mice

Amador‐Noguez, D., Dean, A., Huang, W., Setchell, K., Moore, D., & Darlington, G. (2007) · Aging Cell

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 134

Gene expression profile of long‐lived Ames dwarf mice and Little mice

Amador‐Noguez, D., Yagi, K., Venable, S., & Darlington, G. (2004) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsGrowth Hormone and Insulin-like Growth Factors

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Upregulation of Interleukin 6 and Granulocyte Colony-Stimulating Factor Receptors by Transcription Factor CCAAT Enhancer Binding Protein α (C/EBPα) Is Critical for Granulopoiesis

Zhang, P., Iwama, A., Datta, M. W., Darlington, G. J., Link, D. C., & Tenen, D. G. (1998) · The Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsHematopoietic Stem Cell Transplantation

Cited by 130

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBP

Iwama, A., Zhang, P., Darlington, G. J., McKercher, S. R., Maki, R., & Tenen, D. G. (1998) · Nucleic Acids Research

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 91

CD24-Positive Cells from Normal Adult Mouse Liver Are Hepatocyte Progenitor Cells

Qiu, Q., Hernandez, J. C., Dean, A. M., Rao, P. H., & Darlington, G. J. (2011) · Stem Cells and Development

Liver physiology and pathologyMesenchymal stem cell research

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