Huang, Xingxu

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

Niu, Y., Shen, B., Cui, Y., Chen, Y., Wang, J., Wang, L., Kang, Y., Zhao, X., Si, W., Li, W., et al. (2014) · Cell

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 1,033

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

Shi, H., Zhang, X., Weng, Y.-L., Lu, Z., Liu, Y., Lu, Z., Li, J., Hao, P., Zhang, Y., Zhang, F., et al. (2018) · Nature

RNA modifications and cancerMemory and Neural Mechanisms

Cited by 546

Human regulatory T cells induce T-lymphocyte senescence

Ye, J., Huang, X., Hsueh, E. C., Zhang, Q., Ma, C., Zhang, Y., Varvares, M. A., Hoft, D. F., & Peng, G. (2012) · Blood

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 198

Off-target mutations are rare in Cas9-modified mice

Iyer, V., Shen, B., Zhang, W., Hodgkins, A., Keane, T., Huang, X., & Skarnes, W. C. (2015) · Nature Methods

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 185

IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages

Rao, L.-Z., Wang, Y., Zhang, L., Wu, G., Zhang, L., Wang, F.-X., Chen, L.-M., Sun, F., Jia, S., Zhang, S., et al. (2021) · Cell Death & Differentiation

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes

Cited by 153

Efficient Gene Silencing by Adenine Base Editor-Mediated Start Codon Mutation

Wang, X., Liu, Z., Li, G., Dang, L., Huang, S., He, L., Ma, Y., Li, C., Liu, M., Yang, G., et al. (2020) · Molecular Therapy

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 89

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Li, W., Jiang, X., Wang, W., Hou, L., Cai, R., Li, Y., Gu, Q., Chen, Q., Ma, P., Tang, J., et al. (2024) · Nature Communications

CRISPR and Genetic EngineeringGenomics and Phylogenetic Studies

Cited by 21

Novel CRISPR-Cas12a Clades Discovery Using Large Language Model

Huang, X., Feng, Y., Shi, J., Yang, J., Li, Z., Li, Y., Tang, J., Yang, Y., Zheng, J., Han, W., et al. (2024) · Nature Communications

CRISPR and Genetic EngineeringMachine Learning in Bioinformatics

Cited by 21

Discovery of CRISPR-Cas12a clades using a large language model

Feng, Y., Shi, J., Li, Z., Li, Y., Yang, J., Huang, S., Zheng, J., Han, W., Qiao, Y., Zhang, J., et al. (2025) · Nature Communications

CRISPR and Genetic EngineeringMachine Learning in Bioinformatics

Cited by 21

Unveiling the evolution of antimicrobial peptides in gut microbes via foundation-model-powered framework

Li, W., Huang, B., Guo, M., Zeng, Z., Cai, T., Feng, L., Zhang, X., Guo, L., Jiang, X., Yin, Y., et al. (2025) · Cell Reports

Antimicrobial Peptides and ActivitiesMicrobial Natural Products and Biosynthesis

Cited by 13

Unveiling the Evolution of Antimicrobial Peptides in Gut Microbes via Foundation Model-Powered Framework

Li, W., Huang, B., Guo, M., Zeng, Z., Cai, T., Feng, L., Zhang, X., Guo, L., Jiang, X., Yin, Y., et al. (2025) · Cell Reports

Antimicrobial Peptides and ActivitiesMicrobial Natural Products and Biosynthesis

Cited by 13