Esterlis, Irina

Lower synaptic density is associated with depression severity and network alterations

Holmes, S. E., Scheinost, D., Finnema, S. J., Naganawa, M., Davis, M. T., DellaGioia, N., Nabulsi, N., Matuskey, D., Angarita, G. A., Pietrzak, R. H., et al. (2019) · Nature Communications

Treatment of Major DepressionFunctional Brain Connectivity Studies

Cited by 484

The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects

Abdallah, C. G., De Feyter, H. M., Averill, L. A., Jiang, L., Averill, C. L., Chowdhury, G. M. I., Purohit, P., de Graaf, R. A., Esterlis, I., Juchem, C., et al. (2018) · Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 229

KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID‐ACTING ANTIDEPRESSANTS

Abdallah, C. G., Adams, T. G., Kelmendi, B., Esterlis, I., Sanacora, G., & Krystal, J. H. (2016) · Depression and Anxiety

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 206

The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study

Hannestad, J., DellaGioia, N., Gallezot, J.-D., Lim, K., Nabulsi, N., Esterlis, I., Pittman, B., Lee, J.-Y., O’Connor, K. C., Pelletier, D., et al. (2013) · Brain, Behavior, and Immunity

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 204

β2-Nicotinic Acetylcholine Receptor Availability During Acute and Prolonged Abstinence From Tobacco Smoking

Cosgrove, K. P., Batis, J., Bois, F., Maciejewski, P. K., Esterlis, I., Kloczynski, T., Stiklus, S., Krishnan-Sarin, S., O’Malley, S., Perry, E., et al. (2009) · Archives of General Psychiatry

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 165

Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression

Esterlis, I., DellaGioia, N., Pietrzak, R. H., Matuskey, D., Nabulsi, N., Abdallah, C. G., Yang, J., Pittenger, C., Sanacora, G., Krystal, J. H., et al. (2018) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 148

Persistent β 2 *-Nicotinic Acetylcholinergic Receptor Dysfunction in Major Depressive Disorder

Saricicek, A., Esterlis, I., Maloney, K. H., Mineur, Y. S., Ruf, B. M., Muralidharan, A., Chen, J. I., Cosgrove, K. P., Kerestes, R., Ghose, S., et al. (2012) · American Journal of Psychiatry

Nicotinic Acetylcholine Receptors StudyTreatment of Major Depression

Cited by 118

In vivo evidence of lower synaptic vesicle density in schizophrenia

Radhakrishnan, R., Skosnik, P. D., Ranganathan, M., Naganawa, M., Toyonaga, T., Finnema, S., Hillmer, A. T., Esterlis, I., Huang, Y., Nabulsi, N., et al. (2021) · Molecular Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 100

Imaging the effect of ketamine on synaptic density (SV2A) in the living brain

Holmes, S. E., Finnema, S. J., Naganawa, M., DellaGioia, N., Holden, D., Fowles, K., Davis, M., Ropchan, J., Emory, P., Ye, Y., et al. (2022) · Molecular Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 78

Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder

Scheinost, D., Holmes, S. E., DellaGioia, N., Schleifer, C., Matuskey, D., Abdallah, C. G., Hampson, M., Krystal, J. H., Anticevic, A., & Esterlis, I. (2018) · Neuropsychopharmacology

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 73

Changes in the Cholinergic System between Bipolar Depression and Euthymia as Measured with [123I]5IA Single Photon Emission Computed Tomography

Hannestad, J. O., Cosgrove, K. P., DellaGioia, N. F., Perkins, E., Bois, F., Bhagwagar, Z., Seibyl, J. P., McClure-Begley, T. D., Picciotto, M. R., & Esterlis, I. (2013) · Biological Psychiatry

Bipolar Disorder and TreatmentNicotinic Acetylcholine Receptors Study

Cited by 63

Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies

Esterlis, I., Holmes, S. E., Sharma, P., Krystal, J. H., & DeLorenzo, C. (2018) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 50

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men

Holmes, S. E., Esterlis, I., Mazure, C. M., Lim, Y. Y., Ames, D., Rainey-Smith, S., Martins, R. N., Salvado, O., Dore, V., Villemagne, V. L., et al. (2016) · The American Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 40

Imaging synaptic density in depression

Holmes, S. E., Abdallah, C., & Esterlis, I. (2023) · Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 39

Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11 C‐UCB‐J positron emission tomography study in humans

Angarita, G. A., Worhunsky, P. D., Naganawa, M., Toyonaga, T., Nabulsi, N. B., Li, C. R., Esterlis, I., Skosnik, P. D., Radhakrishnan, R., Pittman, B., et al. (2022) · Addiction Biology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 38

Imaging changes in synaptic acetylcholine availability in living human subjects

Esterlis, I., Hannestad, J. O., Bois, F., Sewell, R. A., Tyndale, R. F., Seibyl, J. P., Picciotto, M. R., Laruelle, M., Carson, R. E., & Cosgrove, K. P. (2013) · Journal of Nuclear Medicine

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 38

Acute cognitive effects of single-dose intravenous ketamine in major depressive and posttraumatic stress disorder

Davis, M. T., DellaGiogia, N., Maruff, P., Pietrzak, R. H., & Esterlis, I. (2021) · Translational Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 37

Ketamine Normalizes the Structural Alterations of Inferior Frontal Gyrus in Depression

Dai, D., Lacadie, C. M., Holmes, S. E., Cool, R., Anticevic, A., Averill, C., Abdallah, C., & Esterlis, I. (2020) · Chronic Stress

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 34

Identifying brain networks in synaptic density PET (11C-UCB-J) with independent component analysis

Fang, X. T., Toyonaga, T., Hillmer, A. T., Matuskey, D., Holmes, S. E., Radhakrishnan, R., Mecca, A. P., van Dyck, C. H., D'Souza, D. C., Esterlis, I., et al. (2021) · NeuroImage

Functional Brain Connectivity StudiesBlind Source Separation Techniques

Cited by 30

Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder

Holmes, S. E., Asch, R. H., Davis, M. T., DellaGioia, N., Pashankar, N., Gallezot, J.-D., Nabulsi, N., Matuskey, D., Sanacora, G., Carson, R. E., et al. (2023) · Biological Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 27

Measuring the effects of ketamine on mGluR5 using [ 18 F]FPEB and PET

Holmes, S. E., Gallezot, J.-D., Davis, M. T., DellaGioia, N., Matuskey, D., Nabulsi, N., Krystal, J. H., Javitch, J. A., DeLorenzo, C., Carson, R. E., et al. (2020) · Journal of Cerebral Blood Flow & Metabolism

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 24

Linking resting-state network fluctuations with systems of coherent synaptic density: A multimodal fMRI and 11C-UCB-J PET study

Fang, X. T., Volpi, T., Holmes, S. E., Esterlis, I., Carson, R. E., & Worhunsky, P. D. (2023) · Frontiers in Human Neuroscience

Functional Brain Connectivity StudiesAdvanced MRI Techniques and Applications

Cited by 18

Challenges and rewards of in vivo synaptic density imaging, and its application to the study of depression

Asch, R. H., Abdallah, C. G., Carson, R. E., & Esterlis, I. (2025) · Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 13

The metabotropic glutamate receptor 5 as a biomarker for psychiatric disorders

Asch, R., Hillmer, A. T., Baldassarri, S. R., & Esterlis, I. (2023) · International Review of Neurobiology

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 8