Cruceanu, Cristiana

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., et al. (2018) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,924

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, Stahl, E. A., BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., et al. (2019) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,519

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

Torres-Platas, S. G., Cruceanu, C., Chen, G. G., Turecki, G., & Mechawar, N. (2014) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 545

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment

Lopez, J. P., Lim, R., Cruceanu, C., Crapper, L., Fasano, C., Labonte, B., Maussion, G., Yang, J. P., Yerko, V., Vigneault, E., et al. (2014) · Nature Medicine

Treatment of Major DepressionMicroRNA in disease regulation

Cited by 308

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

Lopez, J. P., Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., Heller, E. A., Vialou, V., Ku, S. M., Gerald, C., et al. (2017) · Nature Communications

Treatment of Major DepressionMicroRNA in disease regulation

Cited by 201

scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

Schmid, K. T., Höllbacher, B., Cruceanu, C., Böttcher, A., Lickert, H., Binder, E. B., Theis, F. J., & Heinig, M. (2021) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 108

H3K4 tri-methylation in synapsin genes leads to different expression patterns in bipolar disorder and major depression

Cruceanu, C., Alda, M., Nagy, C., Freemantle, E., Rouleau, G. A., & Turecki, G. (2013) · International Journal of Neuropsychopharmacology

Bipolar Disorder and TreatmentEpigenetics and DNA Methylation

Cited by 93

Effects of Postmortem Interval on Biomolecule Integrity in the Brain

Nagy, C., Maheu, M., Lopez, J. P., Vaillancourt, K., Cruceanu, C., Gross, J. A., Arnovitz, M., Mechawar, N., & Turecki, G. (2015) · Journal of Neuropathology & Experimental Neurology

Molecular Biology Techniques and ApplicationsEpigenetics and DNA Methylation

Cited by 79

DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression

Cruceanu, C., Kutsarova, E., Chen, E. S., Checknita, D. R., Nagy, C., Lopez, J. P., Alda, M., Rouleau, G. A., & Turecki, G. (2016) · BMC Psychiatry

Epigenetics and DNA MethylationBipolar Disorder and Treatment

Cited by 35

Interactions of early-life stress with the genome and epigenome: from prenatal stress to psychiatric disorders

Cruceanu, C., Matosin, N., & Binder, E. B. (2017) · Current Opinion in Behavioral Sciences

Maternal Mental Health During Pregnancy and PostpartumChild Abuse and Trauma

Cited by 29