Papadopoulos, Vassilios

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Rupprecht, R., Papadopoulos, V., Rammes, G., Baghai, T. C., Fan, J., Akula, N., Groyer, G., Adams, D., & Schumacher, M. (2010) · Nature Reviews Drug Discovery

Pharmacological Receptor Mechanisms and EffectsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 930

Peripheral-Type Benzodiazepine/Diazepam Binding Inhibitor Receptor: Biological Role in Steroidogenic Cell Function*

PAPADOPOULOS, V. (1993) · Endocrine Reviews

Estrogen and related hormone effectsReceptor Mechanisms and Signaling

Cited by 417

Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states

Rone, M. B., Fan, J., & Papadopoulos, V. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 399

Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

Papadopoulos, V., Amri, H., Boujrad, N., Cascio, C., Culty, M., Garnier, M., Hardwick, M., Li, H., Vidic, B., Brown, A. S., et al. (1997) · Steroids

Mitochondrial Function and PathologySteroid Chemistry and Biochemistry

Cited by 386

The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis

Papadopoulos, V, Mukhin, A. G., Costa, E., & Krueger, K. E. (1990) · Journal of Biological Chemistry

Mitochondrial Function and PathologySperm and Testicular Function

Cited by 346

Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells

Krueger, K. E., & Papadopoulos, V. (1990) · Journal of Biological Chemistry

Mitochondrial Function and PathologyCholesterol and Lipid Metabolism

Cited by 345

Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

Lacapère, J.-J., & Papadopoulos, V. (2003) · Steroids

Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior

Cited by 342

Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

Li, H., Yao, Z.-X., Degenhardt, B., Teper, G., & Papadopoulos, V. (2001) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 317

Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into Leydig cell mitochondria

Hauet, T., Yao, Z.-X., Bose, H. S., Wall, C. T., Han, Z., Li, W., Hales, D. B., Miller, W. L., Culty, M., & Papadopoulos, V. (2005) · Molecular Endocrinology

Mitochondrial Function and PathologySteroid Chemistry and Biochemistry

Cited by 252

Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones

Rone, M. B., Midzak, A. S., Issop, L., Rammouz, G., Jagannathan, S., Fan, J., Ye, X., Blonder, J., Veenstra, T., & Papadopoulos, V. (2012) · Molecular Endocrinology

Mitochondrial Function and PathologySteroid Chemistry and Biochemistry

Cited by 247

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

Liu, J., Rone, M. B., & Papadopoulos, V. (2006) · Journal of Biological Chemistry

Steroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Cited by 241

Cellular sources of TSPO expression in healthy and diseased brain

Nutma, E., Ceyzériat, K., Amor, S., Tsartsalis, S., Millet, P., Owen, D. R., Papadopoulos, V., & Tournier, B. B. (2021) · European Journal of Nuclear Medicine and Molecular Imaging

Neuroinflammation and Neurodegeneration MechanismsPharmacological Receptor Mechanisms and Effects

Cited by 192

In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding

Delavoie, F., Li, H., Hardwick, M., Robert, J.-C., Giatzakis, C., Péranzi, G., Yao, Z.-X., Maccario, J., Lacapère, J.-J., & Papadopoulos, V. (2003) · Biochemistry

Lipid Membrane Structure and BehaviorDrug Transport and Resistance Mechanisms

Cited by 168

In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells

Garnier, M., Dimchev, A. B., Boujrad, N., Price, J. M., Musto, N. A., & Papadopoulos, V (1994) · Molecular Pharmacology

Pharmacological Receptor Mechanisms and EffectsMitochondrial Function and Pathology

Cited by 159

Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3

Issop, L., Fan, J., Lee, S., Rone, M. B., Basu, K., Mui, J., & Papadopoulos, V. (2015) · Endocrinology

Mitochondrial Function and PathologyCaveolin-1 and cellular processes

Cited by 147

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): An emerging signaling molecule

Fan, J., Liu, J., Culty, M., & Papadopoulos, V. (2010) · Progress in Lipid Research

Cellular transport and secretionLipid metabolism and biosynthesis

Cited by 142

Leydig cell aging and hypogonadism

Beattie, M. C., Adekola, L., Papadopoulos, V., Chen, H., & Zirkin, B. R. (2015) · Experimental Gerontology

Hormonal and reproductive studiesSperm and Testicular Function

Cited by 139

Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation

Fan, J., Campioli, E., Midzak, A., Culty, M., & Papadopoulos, V. (2015) · Proceedings of the National Academy of Sciences

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 133

Steroid biosynthesis in adipose tissue

Li, J., Papadopoulos, V., & Vihma, V. (2015) · Steroids

Adipokines, Inflammation, and Metabolic DiseasesLipid metabolism and biosynthesis

Cited by 130

In vitro studies on the role of the peripheral-type benzodiazepine receptor in steroidogenesis

Culty, M., Li, H., Boujrad, N., Amri, H., Vidic, B., Bernassau, J. M., Reversat, J. L., & Papadopoulos, V (1999) · The Journal of Steroid Biochemistry and Molecular Biology

Mitochondrial Function and PathologySteroid Chemistry and Biochemistry

Cited by 122

Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies

Midzak, A., & Papadopoulos, V. (2016) · Frontiers in Endocrinology

Mitochondrial Function and PathologyAdrenal Hormones and Disorders

Cited by 114

Mitochondrial protein import and the genesis of steroidogenic mitochondria

Midzak, A., Rone, M., Aghazadeh, Y., Culty, M., & Papadopoulos, V. (2011) · Molecular and Cellular Endocrinology

Mitochondrial Function and PathologySteroid Chemistry and Biochemistry

Cited by 89

Axonal Regeneration and Neuroinflammation: Roles for the Translocator Protein 18 kDa

Girard, C., Liu, S., Adams, D., Lacroix, C., Sinéus, M., Boucher, C., Papadopoulos, V., Rupprecht, R., Schumacher, M., & Groyer, G. (2012) · Journal of Neuroendocrinology

Nerve injury and regenerationTraumatic Brain Injury and Neurovascular Disturbances

Cited by 75

Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis

Midzak, A., Akula, N., Lecanu, L., & Papadopoulos, V. (2011) · Journal of Biological Chemistry

Steroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Cited by 69