Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states

Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor

Acton, S. L., Rigotti, A., Landschulz, K. T., Xu, S., Hobbs, H. H., & Krieger, M. (1996) · Science · doi:10.1126/science.271.5248.518 · Cited by 2,347 · see citing works

Searching for Peptide Ligands with an Epitope Library

Scott, J. K., & Smith, G. P. (1990) · Science · doi:10.1126/science.1696028 · Cited by 2,087 · see citing works

Protein Sensors for Membrane Sterols

Goldstein, J. L., DeBose‐Boyd, R. A., & Brown, M. S. (2006) · Cell · doi:10.1016/j.cell.2005.12.022 · Cited by 1,685 · see citing works

Cellular cholesterol trafficking and compartmentalization

Ikonen, E. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2336 · Cited by 1,455 · see citing works

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

Papadopoulos, V., Baraldi, M., Guilarte, T. R., Knudsen, T. B., Lacapère, J.-J., Lindemann, P., Norenberg, M. D., Nutt, D., Weizman, A., Zhang, M.-R., et al. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.06.005 · Cited by 1,389 · see citing works

Tat-mediated delivery of heterologous proteins into cells.

Fawell, S. E., Seery, J., Daikh, Y., Moore, C., Chen, L. L., Pepinsky, B., & Barsoum, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.664 · Cited by 1,225 · see citing works

The purification, cloning and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)

Clark, B. J., Wells, J., King, S. R., & Stocco, D. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46930-x · Cited by 1,168 · see citing works

Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex

Kirschner, L. S., Carney, J. A., Pack, S. D., Taymans, S. E., Giatzakis, C., Cho, Y. S., Cho-Chung, Y. S., & Stratakis, C. A. (2000) · Nature Genetics · doi:10.1038/79238 · Cited by 1,153 · see citing works

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

Kokoszka, J. E., Waymire, K. G., Levy, S. E., Sligh, J. E., Cai, J., Jones, D. P., MacGregor, G. R., & Wallace, D. C. (2004) · Nature · doi:10.1038/nature02229 · Cited by 1,086 · see citing works

Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis

Lin, D., Sugawara, T., Strauss, J. F., Clark, B. J., Stocco, D. M., Saenger, P., Rogol, A., & Miller, W. L. (1995) · Science · doi:10.1126/science.7892608 · Cited by 1,030 · see citing works

Rabs and their effectors: achieving specificity in membrane traffic

Grosshans, B. L., Ortiz, D., & Novick, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601617103 · Cited by 1,005 · see citing works

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

McEnery, M. W., Snowman, A. M., Trifiletti, R. R., & Snyder, S. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.8.3170 · Cited by 708 · see citing works

The pathophysiology and genetics of congenital lipoid adrenal hyperplasia

Bose, H. S., Sugawara, T., Strauss, J. F., & Miller, W. L. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612193352503 · Cited by 676 · see citing works

Solution structure of the integral human membrane protein VDAC-1 in detergent micelles

Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008) · Science · doi:10.1126/science.1161302 · Cited by 667 · see citing works

Characterization and measurement of dehydroepiandrosterone sulfate in rat brain

Corpéchot, C., Robel, P., Axelson, M., Sjövall, J., & Baulieu, E. E. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.8.4704 · Cited by 656 · see citing works

NEUROSTEROIDS: A NOVEL FUNCTION OF THE BRAIN

Baulieu, E. E. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00071-7 · Cited by 624 · see citing works

Regulation of Sterol Synthesis in Eukaryotes

Espenshade, P. J., & Hughes, A. L. (2007) · Annual Review of Genetics · doi:10.1146/annurev.genet.41.110306.130315 · Cited by 593 · see citing works

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

Osuga, J.-I., Ishibashi, S., Oka, T., Yagyu, H., Tozawa, R., Fujimoto, A., Shionoiri, F., Yahagi, N., Kraemer, F. B., Tsutsumi, O., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.2.787 · Cited by 586 · see citing works

Kainic acid as a tool for the study of temporal lobe epilepsy

Jv, N. (1981) · Life Sciences · doi:10.1016/0024-3205(81)90659-7 · Cited by 569 · see citing works

ACYL-COENZYME A:CHOLESTEROL ACYLTRANSFERASE

Chang, T., Chang, C. C. Y., & Cheng, D. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.613 · Cited by 554 · see citing works

Neurosteroids: a new brain function?

Baulieu, E., & Robel, P. (1990) · Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(90)90490-c · Cited by 541 · see citing works

Structure and lipid transport mechanism of a StAR-related domain

Tsujishita (2000) · Nature Structural Biology · doi:10.1038/75192 · Cited by 535 · see citing works

Hormone-sensitive lipase

Kraemer, F. B., & Shen, W.-J. (2002) · Journal of Lipid Research · doi:10.1194/jlr.r200009-jlr200 · Cited by 511 · see citing works

Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells

Suchanek, M., Radzikowska, A., & Thiele, C. (2005) · Nature Methods · doi:10.1038/nmeth752 · Cited by 487 · see citing works

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

Infante, R. E., Wang, M. L., Radhakrishnan, A., Kwon, H. J., Brown, M. S., & Goldstein, J. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807328105 · Cited by 485 · see citing works

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11540 · Cited by 449 · see citing works

Peripheral benzodiazepine receptors and mitochondrial function

Casellas, P. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(01)00118-8 · Cited by 446 · see citing works

Peripheral-Type Benzodiazepine/Diazepam Binding Inhibitor Receptor: Biological Role in Steroidogenic Cell Function*

PAPADOPOULOS, V. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-2-222 · Cited by 417 · see citing works

The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria

Stone, S. J., Levin, M. C., Zhou, P., Han, J., Walther, T. C., & Farese, R. V. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m805768200 · Cited by 390 · see citing works

Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

Papadopoulos, V., Amri, H., Boujrad, N., Cascio, C., Culty, M., Garnier, M., Hardwick, M., Li, H., Vidic, B., Brown, A. S., et al. (1997) · Steroids · doi:10.1016/s0039-128x(96)00154-7 · Cited by 386 · see citing works

Pregnenolone and its sulfate ester in the rat brain

Corpéchot, C., Synguelakis, M., Talha, S., Axelson, M., Sjövall, J., Vihko, R., Baulieu, E.-E., & Robel, P. (1983) · Brain Research · doi:10.1016/0006-8993(83)90797-7 · Cited by 385 · see citing works

Give lipids a START: the StAR-related lipid transfer (START) domain in mammals

Alpy, F., & Tomasetto, C. (2005) · Journal of Cell Science · doi:10.1242/jcs.02485 · Cited by 384 · see citing works

Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

Sugawara, T., Holt, J. A., Driscoll, D., Strauss, J. F., Lin, D., Miller, W. L., Patterson, D., Clancy, K. P., Hart, I. M., & Clark, B. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.4778 · Cited by 382 · see citing works

The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis

Papadopoulos, V, Mukhin, A. G., Costa, E., & Krueger, K. E. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39661-9 · Cited by 346 · see citing works

Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells

Krueger, K. E., & Papadopoulos, V. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77217-7 · Cited by 345 · see citing works

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamide

Fur, G. L., Perrier, M. L., Vaucher, N., Imbault, F., Flamier, A., Bénavidès, J., Uzan, A., Renault, C., Dubroeucq, M. C., & Gueremy, C. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90062-0 · Cited by 345 · see citing works

Rab Proteins, Connecting Transport and Vesicle Fusion

Jordens, I., Marsman, M., Kuijl, C. P., & Neefjes, J. (2005) · Traffic · doi:10.1111/j.1600-0854.2005.00336.x · Cited by 344 · see citing works

Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

Lacapère, J.-J., & Papadopoulos, V. (2003) · Steroids · doi:10.1016/s0039-128x(03)00101-6 · Cited by 342 · see citing works

Regulation of intramitochondrial cholesterol transfer to side-chain cleavage cytochrome P-450 in rat adrenal gland.

Privalle, C. T., Crivello, J. F., & Jefcoate, C. R. E. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.3.702 · Cited by 338 · see citing works

Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter

Miller, W. L. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2007.02.012 · Cited by 332 · see citing works

Cholesterol Distribution in Living Cells: Fluorescence Imaging Using Dehydroergosterol as a Fluorescent Cholesterol Analog

Mukherjee, S., Zha, X., Tabas, I. A., & Maxfield, F. R. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77632-5 · Cited by 332 · see citing works

Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

Li, H., Yao, Z.-X., Degenhardt, B., Teper, G., & Papadopoulos, V. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.3.1267 · Cited by 317 · see citing works

SREBPs: the crossroads of physiological and pathological lipid homeostasis

Raghow, R., Yellaturu, C. R., Deng, X., Park, E. A., & Elam, M. B. (2008) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2007.10.009 · Cited by 304 · see citing works

Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

Arakane, F., Sugawara, T., Nishino, H., Liu, Z., Holt, J. A., Pain, D., Stocco, D. M., Miller, W. L., & Strauss, J. F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13731 · Cited by 304 · see citing works

Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor.

Verma, A. M., Nye, J. S., & Snyder, S. H. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.8.2256 · Cited by 301 · see citing works

Intracellular cholesterol transport

Soccio, R. E., & Breslow, J. L. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000131264.66417.d5 · Cited by 297 · see citing works

Regulated Localization of Rab18 to Lipid Droplets

Martin, S., Driessen, K., Nixon, S. J., Zerial, M., & Parton, R. G. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506651200 · Cited by 289 · see citing works

Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene functionPreprint

Seedorf, U., Raabe, M., Ellinghaus, P., Kannenberg, F., Fobker, M., Engel, T., Denis, S. W., Wouters, F., Wirtz, K. W. A., Wanders, R. J. A., et al. (1998) · Genes & Development · doi:10.1101/gad.12.8.1189 · Cited by 268 · see citing works

Lipid droplet-organelle interactions; sharing the fats

Murphy, S., Martin, S., & Parton, R. G. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2008.07.004 · Cited by 265 · see citing works

Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice

Hasegawa, T., Zhao, L., Caron, K. M., Majdic, G., Suzuki, T., Shizawa, S., Sasano, H., & Parker, K. L. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.9.0515 · Cited by 263 · see citing works

Hormone-sensitive lipase - new roles for an old enzyme

Yeaman, S. J. (2004) · Biochemical Journal · doi:10.1042/bj20031811 · Cited by 262 · see citing works

On the Mechanism of Action of ACTH

Garren, L. D., Gill, G. N., Masui, H., & Walton, G. M. (1971) · Elsevier eBooks · doi:10.1016/b978-0-12-571127-2.50035-3 · Cited by 260 · see citing works

Endocytosis: clathrin-mediated membrane budding.

Ungewickell, E., & Hinrichsen, L. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.05.003 · Cited by 257 · see citing works

Mitochondrial benzodiazepine receptors regulate steroid biosynthesis.

Mukhin, A. G., Papadopoulos, V., Costa, E., & Krueger, K. E. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.9813 · Cited by 256 · see citing works

Characterization of the Cholesterol Recognition Amino Acid Consensus Sequence of the Peripheral-Type Benzodiazepine Receptor

Jamin, N., Neumann, J., Ostuni, M. A., Vu, T. K. N., Yao, Z., Murail, S., Robert, J., Giatzakis, C., Papadopoulos, V., & Lacapère, J.-J. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0308 · Cited by 254 · see citing works

Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats

Anholt, R. R., De Souza, E. B., Oster-Granite, M. L., & Snyder, S. H. (1985) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21237-x · Cited by 254 · see citing works

Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into Leydig cell mitochondria

Hauet, T., Yao, Z.-X., Bose, H. S., Wall, C. T., Han, Z., Li, W., Hales, D. B., Miller, W. L., Culty, M., & Papadopoulos, V. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0307 · Cited by 252 · see citing works

Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol

Lange, Y., Ye, J., Rigney, M., & Steck, T. L. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32101-5 · Cited by 248 · see citing works

Identification of Four Novel Human Genes Amplified and Overexpressed in Breast Carcinoma and Localized to the q11-q21.3 Region of Chromosome 17

Tomasetto, C., Régnier, C. H., Moog‐Lutz, C., Mattéi, M., Chenard, M., Lidereau, R., Basset, P., & Rio, M. (1995) · Genomics · doi:10.1006/geno.1995.1163 · Cited by 246 · see citing works

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

Liu, J., Rone, M. B., & Papadopoulos, V. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m608820200 · Cited by 241 · see citing works

Gene structure, intracellular localization, and functional roles of sterol carrier protein-2

Gallegos, A. M., Atshaves, B. P., Storey, S. M., Starodub, O., Petrescu, A. D., Huang, H., McIntosh, A. L., Martin, G. G., Chao, H., Kier, A. B., et al. (2001) · Progress in Lipid Research · doi:10.1016/s0163-7827(01)00015-7 · Cited by 231 · see citing works

Regulation of Peptide Hormone Receptors and Gonadal Steroidogenesis

Catt, K. J., Harwood, J. P., Clayton, R. N., Davies, T. F., Chan, V., Katikineni, M., NOZU, K., & Dufau, M. L. (1980) · Elsevier eBooks · doi:10.1016/b978-0-12-571136-4.50021-8 · Cited by 228 · see citing works

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-(1-methylpropyl)-3 isoquinolinecarboxamide

Fur, G. L., Guilloux, F., Rufat, P., Bénavidès, J., Uzan, A., Renault, C., Dubroeucq, M. C., & Gueremy, C. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90063-2 · Cited by 227 · see citing works

Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor.

Papadopoulos, V., Guarneri, P., Kreuger, K. E., Guidotti, A., & Costa, E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.11.5113 · Cited by 224 · see citing works

Targeted Disruption of the Peripheral-type Benzodiazepine Receptor Gene Inhibits Steroidogenesis in the R2C Leydig Tumor Cell Line

Papadopoulos, V., Amri, H., Li, H., Boujrad, N., Vidić, B., & Garnier, M. J. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.51.32129 · Cited by 219 · see citing works

Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells

Artemenko, I. P., Zhao, D., Hales, D. B., Hales, K. H., & Jefcoate, C. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107815200 · Cited by 217 · see citing works

Steroidogenic Acute Regulatory Protein (StAR) Is A Sterol Transfer Protein

Kallen, C. B., Billheimer, J. T., Summers, S. A., Stayrook, S. E., Lewis, M., & Strauss, J. F. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.41.26285 · Cited by 217 · see citing works

Cellular and Subcellular Localization of Peripheral Benzodiazepine Receptors After Trimethyltin Neurotoxicity

Kuhlmann, A. C., & Guilarte, T. R. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0741694.x · Cited by 215 · see citing works

Acute ACTH regulation of adrenal corticosteroid biosynthesis: rapid accumulation of a phosphoprotein

Pon, L. A., Hartigan, J. A., & Orme-Johnson, N. R. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69305-6 · Cited by 200 · see citing works

Lipid and cholesterol trafficking in NPC

Mukherjee, S., & Maxfield, F. R. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2004.08.009 · Cited by 190 · see citing works

Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex

Simpson, E. R., & Waterman, M. R. (1983) · Canadian Journal of Biochemistry and Cell Biology · doi:10.1139/o83-088 · Cited by 189 · see citing works

The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6

Soccio, R. E., Adams, R. M., Romanowski, M. J., Sehayek, E., Burley, S. K., & Breslow, J. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052143799 · Cited by 188 · see citing works

Fast flip-flop of cholesterol and fatty acids in membranes: implications for membrane transport proteins

Hamilton, J. A. (2003) · Current Opinion in Lipidology · doi:10.1097/00041433-200306000-00006 · Cited by 184 · see citing works

Rab-regulated interaction of early endosomes with lipid droplets

Liu, P., Bartz, R., Zehmer, J. K., Ying, Y., Zhu, M., Serrero, G., & Anderson, R. G. W. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2007.02.004 · Cited by 182 · see citing works

VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis

Veenman, L., Shandalov, Y., & Gavish, M. (2008) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-008-9142-1 · Cited by 181 · see citing works

Uncovering the role of VDAC in the regulation of cell life and death

Shoshan‐Barmatz, V., Keinan, N., & Zaid, H. (2008) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-008-9147-9 · Cited by 179 · see citing works

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production.

Plump, A. S., Erickson, S. K., Weng, W., Partin, J. S., Breslow, J. L., & Williams, D. L. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118716 · Cited by 178 · see citing works

The Steroidogenic Acute Regulatory Protein Homolog MLN64, a Late Endosomal Cholesterol-binding Protein

Alpy, F., Stoeckel, M. E., Dierich, A., Escola, J.-M., Wendling, C., Chenard, M., Vanier, M. T., Gruenberg, J. E., Tomasetto, C., & Rio, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006279200 · Cited by 176 · see citing works

The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

Guidotti, A., Dong, E., Matsumoto, K., Pinna, G., Rasmusson, A. M., & Costa, E. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00129-1 · Cited by 169 · see citing works

MLN64 Mediates Mobilization of Lysosomal Cholesterol to Steroidogenic Mitochondria

Zhang, M., Liu, P., Dwyer, N. K., Christenson, L. K., Fujimoto, T., Martı́nez, F., Comly, M., Hanover, J. A., Blanchette‐Mackie, E. J., & Strauss, J. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200003200 · Cited by 169 · see citing works

Feedback and Hormonal Regulation of Hepatic 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase: The Concept of Cholesterol Buffering Capacity

Ness, G. C., & Chambers, C. M. (2000) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.2000.22359.x · Cited by 168 · see citing works

In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding

Delavoie, F., Li, H., Hardwick, M., Robert, J.-C., Giatzakis, C., Péranzi, G., Yao, Z.-X., Maccario, J., Lacapère, J.-J., & Papadopoulos, V. (2003) · Biochemistry · doi:10.1021/bi0267487 · Cited by 168 · see citing works

Electron microscopic tomography of rat‐liver mitochondria and their interactions with the endoplasmic reticulum

Mannella, C. A., Buttle, K., Rath, B. K., & Marko, M. (1998) · BioFactors · doi:10.1002/biof.5520080309 · Cited by 167 · see citing works

[3H]Ro5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia

Schoemaker, H. E., Morelli, M., Deshmukh, P. P., & Yamamura, H. I. (1982) · Brain Research · doi:10.1016/0006-8993(82)90602-3 · Cited by 160 · see citing works

In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells

Garnier, M., Dimchev, A. B., Boujrad, N., Price, J. M., Musto, N. A., & Papadopoulos, V (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09915-8 · Cited by 159 · see citing works

High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex

Jefcoate, C. R. E. (2002) · Journal of Clinical Investigation · doi:10.1172/jci16771 · Cited by 157 · see citing works

Structural and Functional Study of Reconstituted Peripheral Benzodiazepine Receptor

Lacapère, J.-J., Delavoie, F., Li, H., Péranzi, G., Maccario, J., Papadopoulos, V., & Vidić, B. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4975 · Cited by 156 · see citing works

Acute stimulation of steroidogenesis in corpus luteum and adrenal cortex by peptide hormones. Rapid induction of a similar protein in both tissues.

Pon, L. A., & Orme-Johnson, N. R. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)84604-5 · Cited by 151 · see citing works

START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells

Strauss, J. F., Kishida, T., Christenson, L. K., Fujimoto, T., & Hiroi, H. (2003) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(03)00063-7 · Cited by 150 · see citing works

The pathophysiology and mechanisms of NP-C disease

Sturley, S. L., Patterson, M. C., Balch, W. E., et al. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2004.08.014 · Cited by 147 · see citing works

Distribution and characterization of diazepam binding inhibitor (DBI) in peripheral tissues of rat

Bovolin, P., Schlichting, J., Miyata, M., Ferrarese, C., Guidotti, A., & Alho, H. (1990) · Regulatory Peptides · doi:10.1016/0167-0115(90)90089-f · Cited by 146 · see citing works

Steroidogenic Acute Regulatory Protein

Christenson, L. K., & Strauss, J. F. (2001) · Archives of Medical Research · doi:10.1016/s0188-4409(01)00338-1 · Cited by 146 · see citing works

Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein

Bose, M., Whittal, R. M., Miller, W. L., & Bose, H. S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709221200 · Cited by 143 · see citing works

Identification, Localization, and Function in Steroidogenesis of PAP7: A Peripheral-Type Benzodiazepine Receptor- and PKA (RIα)-Associated Protein

Li, H., Degenhardt, B., Tobin, D., Yao, Z., Taskén, K., & Papadopoulos, V. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.12.0736 · Cited by 139 · see citing works

High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex

Jefcoate, C. R. E. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0216771 · Cited by 138 · see citing works

Steroidogenic Acute Regulatory Protein Binds Cholesterol and Modulates Mitochondrial Membrane Sterol Domain Dynamics

Petrescu, A. D., Gallegos, A. M., Okamura, Y., Strauss, J. F., & Schroeder, F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101939200 · Cited by 133 · see citing works

Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography

Warnock, D. E., Roberts, C., Lutz, M. S., et al. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82184-6 · Cited by 124 · see citing works

Steroidogenic Acute Regulatory Protein and Peripheral-Type Benzodiazepine Receptor Associate at the Mitochondrial Membrane

Rispoli, L. A., Horvat, R. D., Roess, D. A., Barisas, B. G., Juengel, J. L., & NISWENDER, G. D. (2001) · Endocrinology · doi:10.1210/endo.142.1.8052 · Cited by 124 · see citing works

In vitro studies on the role of the peripheral-type benzodiazepine receptor in steroidogenesis

Culty, M., Li, H., Boujrad, N., Amri, H., Vidic, B., Bernassau, J. M., Reversat, J. L., & Papadopoulos, V (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(99)00056-4 · Cited by 122 · see citing works

Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase

Raha, S., Myint, A. T., Johnstone, L., & Robinson, B. H. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00816-4 · Cited by 115 · see citing works

Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis

Lacor, P., Gandolfo, P., Tonon, M.-C., Brault, E., Dalibert, I., Schumacher, M., Benavides, J., & Ferzaz, B. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01105-6 · Cited by 114 · see citing works

Hormone-Sensitive Lipase Is Required for High-Density Lipoprotein Cholesteryl Ester-Supported Adrenal Steroidogenesis

Kraemer, F. B., Shen, W., Harada, K., Patel, S., Osuga, J.-I., Ishibashi, S., & Azhar, S. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0179 · Cited by 105 · see citing works

Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein

Wang, J., Sykes, B. D., & Ryan, R. O. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.032565999 · Cited by 104 · see citing works

Primary Pigmented Nodular Adrenocortical Disease: Reevaluation of a Patient with Carney Complex 27 Years after Unilateral Adrenalectomy

Sarlis, N. J., Chrousos, G. P., Doppman, J. L., Carney, J. A., & Stratakis, C. A. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.4.3857 · Cited by 103 · see citing works

Role of Scavenger Receptors SR-BI and CD36 in Selective Sterol Uptake in the Small Intestine

Werder, M., Han, C., Wehrli, E., Bimmler, D., Schulthess, G., & Hauser, H. (2001) · Biochemistry · doi:10.1021/bi0109820 · Cited by 100 · see citing works

Sterol carrier protein-2: New roles in regulating lipid rafts and signaling

Schroeder, F., Atshaves, B. P., McIntosh, A. L., Gallegos, A. M., Storey, S. M., Parr, R. D., Jefferson, J. R., Ball, J. M., & Kier, A. B. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2007.04.005 · Cited by 97 · see citing works

Regulation of Sterol Transport between Membranes and NPC2

Xu, Z., Farver, W., Kodukula, S., et al. (2008) · Biochemistry · doi:10.1021/bi801328u · Cited by 96 · see citing works

Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology

Brown, R. C. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00048-9 · Cited by 95 · see citing works

Neurosteroids: The StAR Protein in the Brain

Sierra, A. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01226.x · Cited by 93 · see citing works

Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR

Baker, B. Y., Epand, R. F., Epand, R. M., & Miller, W. L. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611221200 · Cited by 89 · see citing works

Roles of the cytoskeleton and motor proteins in endocytic sorting

Murray, J. W., & Wolkoff, A. W. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.07.008 · Cited by 86 · see citing works

SR-BI and cholesterol uptake into steroidogenic cells

Connelly, M. A., & Williams, D. L. (2003) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2003.10.002 · Cited by 84 · see citing works

Characterization of the Rat Star Gene That Encodes the Predominant 3.5-Kilobase Pair mRNA

Ariyoshi, N., Kim, Y.-C., Artemenko, I. P., Bhattacharyya, K. K., & Jefcoate, C. R. E. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.13.7610 · Cited by 84 · see citing works

Topography of the Leydig cell mitochondrial peripheral-type benzodiazepine receptor

Papadopoulosa, V., Boujrada, N., Ikonomovica, M. D., Ferrarab, P., & Vidica, B. (1994) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(94)90061-2 · Cited by 82 · see citing works

Insights into steroidogenic acute regulatory protein (StAR)-dependent cholesterol transfer in mitochondria: evidence from molecular modeling and structure-based thermodynamics supporting the existence of partially unfolded states of StAR

Mathieu, A., Fleury, A., Ducharme, L., Lavigne, P., & LeHoux, J. (2002) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0290327 · Cited by 82 · see citing works

Steroidogenic acute regulatory protein in the brain

Lavaque, E., Sierra, A., Azcoitia, I., & Garcia-Segura, L. M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.05.060 · Cited by 81 · see citing works

Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

Murail, S., Robert, J., Coïc, Y., Neumann, J., Ostuni, M. A., Yao, Z.-X., Papadopoulos, V., Jamin, N., & Lacapère, J.-J. (2008) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.03.012 · Cited by 80 · see citing works

Cholesterol Level Regulates Endosome Motility via Rab Proteins

Chen, H., Yang, J., Low, P. S., & Cheng, J. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.099366 · Cited by 80 · see citing works

PAP7, a PBR/PKA-RIα-associated protein: a new element in the relay of the hormonal induction of steroidogenesis

Liu, J., Li, H., & Papadopoulos, V. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(03)00213-9 · Cited by 79 · see citing works

Interaction of Hormone-sensitive Lipase with Steroidogeneic Acute Regulatory Protein

Shen, W., Patel, S., Natu, V. S., Hong, R., Wang, J. Y., Azhar, S., & Kraemer, F. B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303934200 · Cited by 79 · see citing works

Photoaffinity labeling of peripheral-type benzodiazepine-binding sites.

Doble, A., Ferris, O., Burgevin, M., Ménager, J., Uzan, A., Dubroeucq, M. C., Renault, C., Gueremy, C., & Fur, G. L. (1987) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10320-9 · Cited by 79 · see citing works

Sterol carrier protein-2 expression in mouse L-cell fibroblasts alters cholesterol uptake

Moncecchi, D., Murphy, E. J., & Schroeder, D. R. P. (1996) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(96)00044-6 · Cited by 76 · see citing works

Sterol Carrier Protein-2 Overexpression Enhances Sterol Cycling and Inhibits Cholesterol Ester Synthesis and High Density Lipoprotein Cholesterol Secretion

Baum, C. L., Reschly, E. J., Gayen, A. K., Groh, M. E., & Schadick, K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.10.6490 · Cited by 72 · see citing works

Increase in ?3 (Peripheral-Type Benzodiazepine) binding site densities in different types of human brain tumours

Cornu, P., Bénavidès, J., Scatton, B., Hauw, J., & Philippon, J. H. (1992) · Acta Neurochirurgica · doi:10.1007/bf01541799 · Cited by 68 · see citing works

Transfer of cholesterol between phospholipid vesicles mediated by the steroidogenic acute regulatory protein (StAR)

Tuckey, R. C., Headlam, M. J., Bose, H. S., & Miller, W. L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206965200 · Cited by 67 · see citing works

Role of Cytochromes P-450 in the Biosynthesis of Steroid Hormones

Hall, P. F. (1985) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60065-5 · Cited by 65 · see citing works

Acute action of choriogonadotropin on Leydig tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor

Boujrad, N. (1996) · Endocrinology · doi:10.1210/en.137.12.5727 · Cited by 62 · see citing works

Modulatory action of benzodiazepines on human term placental steroidogenesis in vitro

Barnea, E. R., Fares, F., & Gavish, M. (1989) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(89)90141-x · Cited by 60 · see citing works

SR-BI-directed HDL-cholesteryl ester hydrolysis

Connelly, M. A., Kellner-Weibel, G., Rothblat, G. H., & Williams, D. L. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200186-jlr200 · Cited by 60 · see citing works

Role of exogenous cholesterol in regulation of adrenal steroidogenesis in the rat.

Verschoor-Klootwyk, A. H., Verschoor, L., Azhar, S., & Reaven, G. M. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34432-6 · Cited by 59 · see citing works

The role of diazepam binding inhibitor and its processing products at mitochondrial benzodiazepine receptors: Regulation of steroid biosynthesis

Papadopoulos, V., Berkovich, A., & Krueger, K. E. (1991) · Neuropharmacology · doi:10.1016/s0028-3908(11)80011-0 · Cited by 56 · see citing works

THE STEROIDOGENIC ACUTE REGULATORY PROTEIN, StAR, WORKS ONLY AT THE OUTER MITOCHONDRIAL MEMBRANE

Bose, H. S., Lingappa, V. R., & Miller, W. L. (2002) · Endocrine Research · doi:10.1081/erc-120016800 · Cited by 56 · see citing works

Adenine Nucleotide Translocator Transports Haem Precursors into Mitochondria

Azuma, M., Kabe, Y., Kuramori, C., Kondo, M., Yamaguchi, Y., & Handa, H. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003070 · Cited by 54 · see citing works

Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity

Poderoso, C., Maloberti, P. M., Duarte, A., Neuman, I., Paz, C., Maciel, F. C., & Podesta, E. J. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.10.009 · Cited by 53 · see citing works

Cholesterol binding is a prerequisite for the activity of the steroidogenic acute regulatory protein (StAR)

Roostaee, A., Barbar, É., Lehoux, J., & Lavigne, P. (2008) · Biochemical Journal · doi:10.1042/bj20071264 · Cited by 51 · see citing works

Constitutive Steroidogenesis in the R2C Leydig Tumor Cell Line Is Maintained by the Adenosine 3′,5′-Cyclic Monophosphate-Independent Production of a Cycloheximide-Sensitive Factor that Enhances Mitochondrial Pregnenolone Biosynthesis*

Freeman, D. A. (1987) · Endocrinology · doi:10.1210/endo-120-1-124 · Cited by 51 · see citing works

More than 1,000 putative new human signalling proteins revealed by EST data mining

Schultz, J., Doerks, T., Ponting, C. P., et al. (2000) · Nature Genetics · doi:10.1038/76069 · Cited by 50 · see citing works

A potential role for sterol carrier protein-2 in cholesterol transfer to mitochondria

Gallegos, A. M., Schoer, J. K., Starodub, O., Kier, A. B., Billheimer, J. T., & Schroeder, F. (2000) · Chemistry and Physics of Lipids · doi:10.1016/s0009-3084(99)00128-0 · Cited by 49 · see citing works

PERIPHERAL-TYPE BENZODIAZEPINE BINDING IN ALZHEIMER DISEASE

McGeer, E. G., Singh, E. A., & McGeer, P. L. (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802040-00001 · Cited by 49 · see citing works

NPC1-Containing Compartment of Human Granulosa-Lutein Cells: A Role in the Intracellular Trafficking of Cholesterol Supporting Steroidogenesis

Watari, H., Blanchette‐Mackie, E. J., Dwyer, N. K., Sun, G.-S., Glick, J. M., Patel, S. C., Neufeld, E. B., Pentchev, P. G., & Strauss, J. F. (2000) · Experimental Cell Research · doi:10.1006/excr.1999.4774 · Cited by 49 · see citing works

Solubilization and reconstitution of the mitochondrial benzodiazepine receptor

Anholt, R. R. H., Aebi, U., Pedersen, P. L., & Snyder, S. H. (1986) · Biochemistry · doi:10.1021/bi00356a041 · Cited by 49 · see citing works

Identification of naturally occurring spirostenols preventing β-amyloid-induced neurotoxicity

Lecanu, L., Yao, W., Teper, G., Yao, Z., Greeson, J., & Papadopoulos, V. (2003) · Steroids · doi:10.1016/j.steroids.2003.09.007 · Cited by 48 · see citing works

Hormonal Regulation of Peripheral Benzodiazepine Receptor Binding Properties Is Mediated by Subunit Interaction

Golani, I., Weizman, A., Leschiner, S., Spanier, I., Eckstein, N., Limor, R., Yanai, J., Maaser, K., Scherübl, H., Weisinger, G., et al. (2001) · Biochemistry · doi:10.1021/bi010431+ · Cited by 48 · see citing works

Two cellular and subcellular locations for the peripheral-type benzodiazepine receptor in rat liver

Woods, M. J., Zisterer, D. M., & Williams, D. C. (1996) · Biochemical Pharmacology · doi:10.1016/0006-2952(96)00034-2 · Cited by 47 · see citing works

The voltage dependent anion channel affects mitochondrial cholesterol distribution and function

Campbell, A. M., & Chan, S. H. P. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2007.06.012 · Cited by 47 · see citing works

Characterization of a peripheral‐type benzodiazepine‐binding site in the mitochondria of Chinese hamster ovary cells

Riond, J., Vita, N., Fur, G. L., & Ferrara, P. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)80229-7 · Cited by 44 · see citing works

Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands

Falchi, A. M., Batetta, B., Sanna, F., Piludu, M., Sogos, V., Serra, M., Melis, M., Putzolu, M., & Diaz, G. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.05.016 · Cited by 43 · see citing works

Sterols and intracellular vesicular trafficking: lessons from the study of NPC1

Strauss, J. F., Liu, P., Christenson, L. K., & Watari, H. (2002) · Steroids · doi:10.1016/s0039-128x(02)00042-9 · Cited by 38 · see citing works

Molecular cloning, chromosomal localization of human peripheral‐type benzodiazepine receptor‐ and protein kinase A regulatory subunit type 1A (PRKAR1A)‐associated protein PAP7 and studies in PRKAR1A mutant cells and tissues

Liu, J., Matyakhina, L., Han, Z. J., Sandrini, F., Bei, T. A., Stratakis, C. A., & Papadopoulos, V. (2003) · The FASEB Journal · doi:10.1096/fj.02-1066fje · Cited by 36 · see citing works

The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain

King, S. R., Ginsberg, S. D., Ishii, T., Smith, R. G., Parker, K. L., & Lamb, D. J. (2004) · Endocrinology · doi:10.1210/en.2003-1740 · Cited by 34 · see citing works

The LDL receptor is not necessary for acute adrenal steroidogenesis in mouse adrenocortical cells

Kraemer, F. B., Shen, W., Patel, S., Osuga, J.-I., Ishibashi, S., & Azhar, S. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00428.2006 · Cited by 34 · see citing works

Toward the NMR structure of StAR

Barbar, É., Lehoux, J., & Lavigne, P. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.12.007 · Cited by 32 · see citing works

Studies on the Phosphorylation of the 18 kDa Mitochondrial Benzodiazepine Receptor Protein

Whalin, M. E., Boujrad, N., Papadopoulos, V., & Krueger, K. E. (1994) · Journal of Receptor Research · doi:10.3109/10799899409066033 · Cited by 32 · see citing works

Identification of a Peptide Antagonist to the Peripheral-Type Benzodiazepine Receptor That Inhibits Hormone-Stimulated Leydig Cell Steroid Formation

Gazouli, M., Han, Z. J., & Papadopoulos, V. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.039388 · Cited by 28 · see citing works

Peripheral-type benzodiazepine receptor (PBR) aggregation and absence of steroidogenic acute regulatory protein (StAR)/PBR association in the mitochondrial membrane as determined by bioluminescence resonance energy transfer (BRET)

Bogan, R. L., Davis, T. L., & NISWENDER, G. D. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.10.007 · Cited by 27 · see citing works

A-Kinase Anchoring Proteins as the Basis for cAMP Signaling

Dodge‐Kafka, K. L., Bauman, A. L., & Kapiloff, M. S. (2008) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-72843-6_1 · Cited by 25 · see citing works

CSF diazepam binding inhibitor and schizophrenia: Clinical and biochemical relationships

van Kammen, D. P., Guidotti, A., Kelley, M. E., Gurklis, J. A., Guarneri, P., Gilbertson, M. W., Yao, J. K., Peters, J., & Costa, E. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90193-h · Cited by 23 · see citing works

Cellular events involved in hormonal control of receptor-mediated endocytosis: regulation occurs at multiple sites in the low density lipoprotein pathway, including steps beyond the receptor.

Foster, J. D., Strauss, J. F., & Paavola, L. G. (1993) · Endocrinology · doi:10.1210/endo.132.1.8419131 · Cited by 18 · see citing works

THE ROLE AND REGULATION OF THE NIEMANN-PICK C1 GENE IN ADRENAL STEROIDOGENESIS

Gévry, N. Y., & Murphy, B. D. (2002) · Endocrine Research · doi:10.1081/erc-120016815 · Cited by 17 · see citing works

Determination of tumor-related factors of influence on the uptake of the monoclonal antibody 323/A3 in experimental human ovarian cancer

Moog-Lutz (1997) · Pure Amsterdam UMC · doi:10.1002/(sici)1097-0215(19970410)71:2

Untitled work

(1997) · doi:10.1002/(sici)1097-4547(19971015)50:2

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Rupprecht, R., Papadopoulos, V., Rammes, G., Baghai, T. C., Fan, J., Akula, N., Groyer, G., Adams, D., & Schumacher, M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3295 · Cited by 930 · see citing works

Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

Adibhatla, R. M., & Hatcher, J. F. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2668 · Cited by 480 · see citing works

Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones

Rone, M. B., Midzak, A. S., Issop, L., Rammouz, G., Jagannathan, S., Fan, J., Ye, X., Blonder, J., Veenstra, T., & Papadopoulos, V. (2012) · Molecular Endocrinology · doi:10.1210/me.2012-1159 · Cited by 247 · see citing works

Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis

Tu, L. N., Morohaku, K., Manna, P. R., Pelton, S. H., Butler, W. R., Stocco, D. M., & Selvaraj, V. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.578286 · Cited by 239 · see citing works

Disorders in the initial steps of steroid hormone synthesis

Miller, W. L. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.03.009 · Cited by 205 · see citing works

Regulation of aldosterone synthesis and secretion.

Bollag, W. B. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c130037 · Cited by 180 · see citing works

VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress

Shoshan-Barmatz, V., N. Maldonado, E., & Krelin, Y. (2017) · Cell Stress · doi:10.15698/cst2017.10.104 · Cited by 170 · see citing works

Mitochondrial fusion is essential for steroid biosynthesis

Duarte, A., Poderoso, C., Cooke, M., Soria, G., Cornejo Maciel, F., Gottifredi, V., & Podestá, E. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045829 · Cited by 149 · see citing works

Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3

Issop, L., Fan, J., Lee, S., Rone, M. B., Basu, K., Mui, J., & Papadopoulos, V. (2015) · Endocrinology · doi:10.1210/en.2014-1503 · Cited by 147 · see citing works

Leydig cell aging and hypogonadism

Beattie, M. C., Adekola, L., Papadopoulos, V., Chen, H., & Zirkin, B. R. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2015.02.014 · Cited by 139 · see citing works

Steroid biosynthesis in adipose tissue

Li, J., Papadopoulos, V., & Vihma, V. (2015) · Steroids · doi:10.1016/j.steroids.2015.03.016 · Cited by 130 · see citing works

Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function

Martin, L. A., Kennedy, B. E., & Karten, B. (2016) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-014-9592-6 · Cited by 128 · see citing works

Imaging Striatal Microglial Activation in Patients with Parkinson’s Disease

Koshimori, Y., Ko, J.-H., Mizrahi, R., Rusjan, P., Mabrouk, R., Jacobs, M. F., Christopher, L., Hamani, C., Lang, A. E., Wilson, A. A., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0138721 · Cited by 100 · see citing works

60 YEARS OF POMC: Adrenal and extra-adrenal functions of ACTH

Gallo-Payet, N. (2016) · Journal of Molecular Endocrinology · doi:10.1530/jme-15-0257 · Cited by 98 · see citing works

Allopregnanolone and neuroinflammation: a focus on multiple sclerosis

Noorbakhsh, F., Baker, G. B., & Power, C. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00134 · Cited by 95 · see citing works

Clinical, genetic, and functional characterization of four patients carrying partial loss-of-function mutations in the steroidogenic acute regulatory protein (StAR)

Sahakitrungruang, T., Soccio, R. E., Lang-Muritano, M., Walker, J. M., Achermann, J. C., & Miller, W. L. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0437 · Cited by 91 · see citing works

Mitochondrial protein import and the genesis of steroidogenic mitochondria

Midzak, A., Rone, M., Aghazadeh, Y., Culty, M., & Papadopoulos, V. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.12.007 · Cited by 89 · see citing works

Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis

Midzak, A., Akula, N., Lecanu, L., & Papadopoulos, V. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.203216 · Cited by 69 · see citing works

The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals

Costa, B., Pini, S., Gabelloni, P., Da Pozzo, E., Abelli, M., Lari, L., Preve, M., Lucacchini, A., Cassano, G. B., & Martini, C. (2009) · Endocrinology · doi:10.1210/en.2009-0752 · Cited by 68 · see citing works

Expression and roles of steroidogenic acute regulatory (StAR) protein in 'non-classical', extra-adrenal and extra-gonadal cells and tissues

Anuka, E., Gal, M., Stocco, D. M., & Orly, J. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.02.003 · Cited by 60 · see citing works

Role of Mitochondria in Steroidogenesis

Miller, W. L. (2011) · Endocrine Development · doi:10.1159/000321204 · Cited by 57 · see citing works

Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress

Korytowski, W., Wawak, K., Pabisz, P., Schmitt, J. C., Chadwick, A. C., Sahoo, D., & Girotti, A. W. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.115.306210 · Cited by 49 · see citing works

Evolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animals

Fan, J., & Papadopoulos, V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076701 · Cited by 48 · see citing works

Phytoecdysteroids and flavonoid glycosides among Chilean and commercial sources of <i>Chenopodium quinoa</i>: variation and correlation to physico‐chemical characteristics

Graf, B. L., Rojo, L. E., Delatorre‐Herrera, J., Poulev, A., Calfio, C., & Raskin, I. (2016) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.7134 · Cited by 46 · see citing works

Signal Transduction of Steroidogenic Hormones to the Adrenal and Gonadal Mitochondria and the Possibilities for Combating Lipoid Congenital Adrenal Hyperplasia

Thomson, M. (2010) · Current Signal Transduction Therapy · doi:10.2174/157436210791112181 · Cited by 2 · see citing works

StAR protein and the regulation of steroid hormone biosynthesis.

Stocco, D. M. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.193 · Cited by 917 · see citing works

A brief history of the search for the protein(s) involved in the acute regulation of steroidogenesis

Stocco, D. M., Zhao, A. H., Tu, L. N., Morohaku, K., & Selvaraj, V. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.07.036 · Cited by 81 · see citing works

106 Randel Lecture: The history of the discovery of the Steroidogenic Acute Regulatory (StAR) Protein

Stocco, D. M. (2019) · Journal of Animal Science · doi:10.1093/jas/skz053.088

Ligand-Induced Activation of Translocator Protein (TSPO) Induces Cholesterol Transport and Steroidogenesis in Aged Leydig Cells.

Chung, J., Chen, H., Papadopoulos, V. D., et al. (2011) · Biology of Reproduction · doi:10.1093/biolreprod/85.s1.562