Knopman, David S.

Frontotemporal dementia and its subtypes: a genome-wide association study

Ferrari, R., Hernandez, D. G., Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B. J., Dobson-Stone, C., Brooks, W. S., Schofield, P. R., Halliday, G. M., et al. (2014) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Procedural learning is impaired in Huntington's disease: Evidence from the serial reaction time task

Knopman, D., & Nissen, M. J. (1991) · Neuropsychologia

Genetic Neurodegenerative DiseasesMotor Control and Adaptation

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Association of midlife to late-life blood pressure patterns with incident dementia

Walker, K. A., Sharrett, A. R., Wu, A., Schneider, A. L. C., Albert, M., Lutsey, P. L., Bandeen-Roche, K., Coresh, J., Gross, A. L., Windham, B. G., et al. (2019) · JAMA

Dementia and Cognitive Impairment ResearchBlood Pressure and Hypertension Studies

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MRI correlates of neurofibrillary tangle pathology at autopsy: A voxel-based morphometry study

Whitwell, J. L., Josephs, K. A., Murray, M. E., Kantarci, K., Przybelski, S. A., Weigand, S. D., Vemuri, P., Senjem, M. L., Parisi, J. E., Knopman, D. S., et al. (2008) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 376

Physical Exercise, Aging, and Mild Cognitive Impairment: A Population-Based Study

Geda, Y. E., Roberts, R. O., Knopman, D. S., Christianson, T. J. H., Pankratz, V. S., Ivnik, R. J., Boeve, B. F., Tangalos, E. G., Petersen, R. C., & Rocca, W. A. (2010) · Archives of Neurology

Dementia and Cognitive Impairment ResearchPhysical Activity and Health

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Age-related changes in the default mode network are more advanced in Alzheimer disease

Jones, D. T., Machulda, M. M., Vemuri, P., McDade, E. M., Zeng, G., Senjem, M. L., Gunter, J. L., Przybelski, S. A., Avula, R. T., Knopman, D. S., et al. (2011) · Neurology

Functional Brain Connectivity StudiesDementia and Cognitive Impairment Research

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Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50–89 years: a cross-sectional study

Jack, C. R., Wiste, H. J., Weigand, S. D., Rocca, W. A., Knopman, D. S., Mielke, M. M., Lowe, V. J., Senjem, M. L., Gunter, J. L., Preboske, G. M., et al. (2014) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?

Clark, C. M., Xie, S., Chittams, J., Ewbank, D., Peskind, E., Galasko, D., Morris, J. C., McKeel, D. W., Farlow, M., Weitlauf, S. L., et al. (2003) · Archives of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50–95 years: a cross-sectional study

Jack, C. R., Wiste, H. J., Weigand, S. D., Therneau, T. M., Knopman, D. S., Lowe, V., Vemuri, P., Mielke, M. M., Roberts, R. O., Machulda, M. M., et al. (2017) · The Lancet Neurology

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Clinicopathologic and11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer’s disease spectrum

Murray, M. E., Lowe, V. J., Graff-Radford, N. R., Liesinger, A. M., Cannon, A., Przybelski, S. A., Rawal, B., Parisi, J. E., Petersen, R. C., Kantarci, K., et al. (2015) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Associations of amyloid, tau, and neurodegeneration biomarker profiles with rates of memory decline among individuals without dementia

Jack, C. R., Wiste, H. J., Therneau, T. M., Weigand, S. D., Knopman, D. S., Mielke, M. M., Lowe, V. J., Vemuri, P., Machulda, M. M., Schwarz, C. G., et al. (2019) · JAMA

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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The NIH Cognitive and Emotional Health Project: Report of the Critical Evaluation Study Committee

Hendrie, H. C., Albert, M. S., Butters, M. A., Gao, S., Knopman, D. S., Launer, L. J., Yaffe, K., Cuthbert, B. N., Edwards, E., & Wagster, M. V. (2006) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAging, Health, and Disability

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Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

Moore, K. M., Nicholas, J., Grossman, M., McMillan, C. T., Irwin, D. J., Massimo, L., Van Deerlin, V. M., Warren, J. D., Fox, N. C., Rossor, M. N., et al. (2020) · The Lancet Neurology

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Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease

Pottier, C., Bieniek, K. F., Finch, N., van de Vorst, M., Baker, M., Perkersen, R., Brown, P., Ravenscroft, T., van Blitterswijk, M., Nicholson, A. M., et al. (2015) · Acta Neuropathologica

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Prevalence of biologically vs clinically defined alzheimer spectrum entities using the National Institute on Aging–Alzheimer's Association Research Framework

Jack, C. R., Therneau, T. M., Weigand, S. D., Wiste, H. J., Knopman, D. S., Vemuri, P., Lowe, V. J., Mielke, M. M., Roberts, R. O., Machulda, M. M., et al. (2019) · JAMA Neurology

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Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyMemory and Neural Mechanisms

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Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly

Vemuri, P., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Preboske, G. M., Kantarci, K., Raman, M. R., Machulda, M. M., Mielke, M. M., Lowe, V. J., et al. (2015) · Brain

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

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Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

Boxer, A. L., Lang, A. E., Grossman, M., Knopman, D. S., Miller, B. L., Schneider, L. S., Doody, R. S., Lees, A., Golbe, L. I., Williams, D. R., et al. (2014) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

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Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study

Walker, K. A., Gottesman, R. F., Wu, A., Knopman, D. S., Gross, A. L., Mosley, T. H., Selvin, E., & Windham, B. G. (2019) · Neurology

Dementia and Cognitive Impairment ResearchAdipokines, Inflammation, and Metabolic Diseases

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Mild cognitive impairment due to Alzheimer disease in the community

Petersen, R. C., Aisen, P., Boeve, B. F., Geda, Y. E., Ivnik, R. J., Knopman, D. S., Mielke, M., Pankratz, V. S., Roberts, R., Rocca, W. A., et al. (2013) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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White matter hyperintensities: relationship to amyloid and tau burden

Graff-Radford, J., Arenaza-Urquijo, E. M., Knopman, D. S., Schwarz, C. G., Brown, R. D., Rabinstein, A. A., Gunter, J. L., Senjem, M. L., Przybelski, S. A., Lesnick, T., et al. (2019) · Brain

Dementia and Cognitive Impairment ResearchCerebrovascular and genetic disorders

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Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer’s disease: A longitudinal retrospective study

Josephs, K. A., Dickson, D. W., Tosakulwong, N., Weigand, S. D., Murray, M. E., Petrucelli, L., Liesinger, A. M., Senjem, M. L., Spychalla, A. J., Knopman, D. S., et al. (2017) · The Lancet Neurology

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Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes

Mielke, M. M., Frank, R. D., Dage, J. L., Jeromin, A., Ashton, N. J., Blennow, K., Karikari, T. K., Vanmechelen, E., Zetterberg, H., Algeciras-Schimnich, A., et al. (2021) · JAMA Neurology

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TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

Finch, N., Carrasquillo, M. M., Baker, M., Rutherford, N. J., Coppola, G., DeJesus-Hernandez, M., Crook, R., Hunter, T., Ghidoni, R., Benussi, L., et al. (2011) · Neurology

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