Penninger, Josef M.

Genome-wide spatial expression profiling in formalin-fixed tissues

Gracia Villacampa, E., Larsson, L., Mirzazadeh, R., Kvastad, L., Andersson, A., Mollbrink, A., Kokaraki, G., Monteil, V., Schultz, N., Appelberg, K. S., et al. (2021) · Cell Genomics

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 132

Afatinib restrains K-RAS–driven lung tumorigenesis

Moll, H. P., Pranz, K., Musteanu, M., Grabner, B., Hruschka, N., Mohrherr, J., Aigner, P., Stiedl, P., Brcic, L., Laszlo, V., et al. (2018) · Science Translational Medicine

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 125

Inhibition of CBLB protects from lethal Candida albicans sepsis

Wirnsberger, G., Zwolanek, F., Asaoka, T., Kozieradzki, I., Tortola, L., Wimmer, R. A., Kavirayani, A., Fresser, F., Baier, G., Langdon, W. Y., et al. (2016) · Nature Medicine

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 113

Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis

Opavsky, M. A., Martino, T., Rabinovitch, M., Penninger, J., Richardson, C., Petric, M., Trinidad, C., Butcher, L., Chan, J., & Liu, P. P. (2002) · Journal of Clinical Investigation

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 91

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

Tsvetkov, P., Mendillo, M. L., Zhao, J., Carette, J. E., Merrill, P. H., Cikes, D., Varadarajan, M., van Diemen, F. R., Penninger, J. M., Goldberg, A. L., et al. (2015) · eLife

Ubiquitin and proteasome pathwaysHeat shock proteins research

Cited by 83

Stimulation of Bone Formation in Cortical Bone of Mice Treated with a Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity

Furuya, Y., Inagaki, A., Khan, M., Mori, K., Penninger, J. M., Nakamura, M., Udagawa, N., Aoki, K., Ohya, K., Uchida, K., et al. (2013) · Journal of Biological Chemistry

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 77

RANKL/RANK: from bone loss to the prevention of breast cancer

Sigl, V., Jones, L. P., & Penninger, J. M. (2016) · Open Biology

BRCA gene mutations in cancerBone Metabolism and Diseases

Cited by 76

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

Tortola, L., Nitsch, R., Bertrand, M. J. M., Kogler, M., Redouane, Y., Kozieradzki, I., Uribesalgo, I., Fennell, L. M., Daugaard, M., Klug, H., et al. (2016) · Cell Reports

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 64

Genetically corrected iPSCs as cell therapy for recessive dystrophic epidermolysis bullosa

Wenzel, D., Bayerl, J., Nyström, A., Bruckner-Tuderman, L., Meixner, A., & Penninger, J. M. (2014) · Science Translational Medicine

Skin and Cellular Biology ResearchPluripotent Stem Cells Research

Cited by 62

Osteoprotegerin Protects against Muscular Dystrophy

Dufresne, S. S., Dumont, N. A., Bouchard, P., Lavergne, É., Penninger, J. M., & Frenette, J. (2015) · The American Journal of Pathology

Muscle Physiology and DisordersBone Metabolism and Diseases

Cited by 61

Genetic deletion of muscle RANK or selective inhibition of RANKL is not as effective as full-length OPG-fc in mitigating muscular dystrophy

Dufresne, S. S., Boulanger-Piette, A., Bossé, S., Argaw, A., Hamoudi, D., Marcadet, L., Gamu, D., Fajardo, V. A., Yagita, H., Penninger, J. M., et al. (2018) · Acta Neuropathologica Communications

Muscle Physiology and DisordersBone Metabolism and Diseases

Cited by 59

Adoptive transfer of siRNA Cblb-silenced CD8+ T lymphocytes augments tumor vaccine efficacy in a B16 melanoma model

Hinterleitner, R., Gruber, T., Pfeifhofer-Obermair, C., Lutz-Nicoladoni, C., Tzankov, A., Schuster, M., Penninger, J. M., Loibner, H., Lametschwandtner, G., Wolf, D., et al. (2012) · PLoS ONE

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 59

Adult T-cells impair neonatal cardiac regeneration

Dolejsi, T., Delgobo, M., Schuetz, T., Tortola, L., Heinze, K. G., Hofmann, U., Frantz, S., Bauer, A., Ruschitzka, F., Penninger, J. M., et al. (2022) · European Heart Journal

Congenital heart defects researchCardiac Fibrosis and Remodeling

Cited by 53

Osteoprotegerin reduces the serum level of receptor activator of NF-κB ligand derived from osteoblasts.

Nakamichi, Y., Udagawa, N., Kobayashi, Y., Nakamura, M., Yamamoto, Y., Yamashita, T., Mizoguchi, T., Sato, M., Mogi, M., Penninger, J. M., et al. (2007) · The Journal of Immunology

Bone Metabolism and DiseasesNF-κB Signaling Pathways

Cited by 50

CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression

Jonsson, G., Hofmann, M., Mereiter, S., Hartley-Tassell, L., Sakic, I., Oliveira, T., Hoffmann, D., Novatchkova, M., Schleiffer, A., & Penninger, J. M. (2024) · FEBS Journal

Renal cell carcinoma treatmentGlycosylation and Glycoproteins Research

Cited by 1

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

Jonsson, G., Hofmann, M., Mereiter, S., Hartley‐Tassell, L., Onji, M., Sakic, I., Oliveira, T., Hoffmann, D., Novatchkova, M., Schleiffer, A., et al. (2026) · The FEBS Journal

Renal cell carcinoma treatmentGlycosylation and Glycoproteins Research

Cited by 1